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  • Katholieke Universiteit Leuven (KU Leuven)
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Summary

VOLLEDIGE Samenvatting Hoofdstuk 5: KREB Cyclus (Biochemie, 1ste BMW)

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Uitgebreide, Volledige Samenvatting van Hoofdstuk 5 van het vak Biochemie en Moleculaire Biologie, in het 1ste jaar Biomedische wetenschappen. Ik heb zelf alles geleerd uit deze samenvatting en was geslaagd in de eerste zit.

Institution
Katholieke Universiteit Leuven (KU Leuven)
Course
Biochemie en moleculaire biologie








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Institution
Katholieke Universiteit Leuven (KU Leuven)
Study
Biomedische Wetenschappen
Course
Biochemie en moleculaire biologie
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Document information

Uploaded on
July 13, 2025
Number of pages
4
Written in
2024/2025
Type
Summary

Subjects

  • kreb cyclus
  • biochemie
  • verschillende stappen
  • hoofdstuk 5

Content preview

Stappenplan KREBscyclus

Stap 1 De citraat synthase reactie


Acetyl CoA (C2) en oxaalazijnzuur (C4) binden aan elkaar (=

CONDENSATIE)


Het intermediair ondergaat een hydrolyse (Water wordt toegevoegd) zodanig

dat CoA loskomt en citraat wordt gevormd




Stap 2 De Aconitase reactie

= Omzetting van citraat naar isocitraat

Intermediair tussen de twee: Cisaconitaat



Eerst wordt er water onttrokken: Hierdoor wordt er een dubbele binding

gevormd

Daarna wordt er water terug toegevoegd en ontstaat er isocitraat (OH-groep

ontstaat)
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