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VOLLEDIGE Samenvatting Hoofdstuk 5: Glycolyse (Biochemie, 1ste BMW)

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Uitgebreide, Volledige Samenvatting van Hoofdstuk 5 van het vak Biochemie en Moleculaire Biologie, in het 1ste jaar Biomedische wetenschappen. Ik heb zelf alles geleerd uit deze samenvatting en was geslaagd in de eerste zit.

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July 13, 2025
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2024/2025
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Stappen van de Glycolyse


Stap 1 Hexokinase reactie




Enzym: Hexokinase
Zal Glucose fosforyleren op positie 6. Er wordt ATP gebruikt


Glucose -> Glucose 6-fosfaat



Stap 2 Fosfohexose isomerase reactie




Enzym: Fosfoglucose isomerase
Van een zesring naar een vijfring


Glucose 5-fosfaat -> Fructose-6-fosfaat


De ring wordt korter afgesloten



1

, Stap 3 Fosfofructokinase reactie




Dit is een regelende stap, gaat de snelheid bepalen
Enzym: Fosfofructokinase
= Fosforyleren van de fructose op positie 1


Fructose 6-fosfaat -> Fructose 1,6-bifosfaat
Er wordt een ATP gebruikt



Stap 4 Aldolase reactie




De 6-koolstof suiker wordt gesplitst in twee 3-koolstofmoleculen
De twee 3-koolstofmoleculen zijn: Dihydroxyacetine fosfaat en
Glyceraldehyde 3-fosfaat


Dihydroxyacetine fosfaat is een dood punt en moet omgezet worden in
glyceraldehyde 3-fosfaat


Fructose 1,6-bifosfaat -> Dihydroxyacetone fosfaat en Glyceraldehyde
3-fosfaat



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