PSIO 303 - Study Guide QUESTIONS WITH ANSWERS

PSIO 303 - Study Guide QUESTIONS WITH \| \| \| \| \| \| \|




ANSWERS

Primary Ciliary Dyskinesia is a condition in which the cilia of cells
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in the respiratory tract are defective. A protein mutation causes
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these cilia to be defective. What type of protein filament does the
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ciliary mutation affect? - CORRECT ANSWERS ✔✔Microtubules
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Which of these processes is Dynein most likely to be involved
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in? - CORRECT ANSWERS ✔✔Retrograde fast axonal transport
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Angiotensin-Converting Enzyme 2 (ACE-2) is an integral \| \| \| \| \| \| \|


membrane protein. As well as being an enzyme it is happens to \| \| \| \| \| \| \| \| \| \| \| \|


be a binding site for the spike protein of the SARS-Cov2
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coronavirus. The virus particle attaches to a host's cell via ACE-2 \| \| \| \| \| \| \| \| \| \| \|


and is then taken into the cell by endocytosis. In cells of the
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human upper airway, where does ACE2 protein synthesis most
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probably occur? - CORRECT ANSWERS ✔✔Ribosomes attached to
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the endoplasmic reticulum
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Choose the best answer that completes the following sentence>
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In the process of fast axonal transport, cargo is carried by motor
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proteins that move along structures that are made of ... -
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CORRECT ANSWERS ✔✔Tubulin \| \|




Is the diameter of a microtubule greater than the thickness of a
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plasma membrane? - CORRECT ANSWERS ✔✔yes \| \| \| \| \|

, What is the Nernst Equation used for? - CORRECT ANSWERS
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✔✔The Nernst Equation is used to calculate the equilibrium
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potential of an ion. \| \| \|




In a typical plasma membrane the width of lipid bilayer is 5-6
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nm. What is your best estimate of the width of the lipid bilayer
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in a typical endoplasmic reticulum (ER) membrane? - CORRECT
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ANSWERS ✔✔5-6 nm \| \|




Why are integral membrane proteins translated at the rough
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endoplasmic reticulum? - CORRECT ANSWERS ✔✔Integral \| \| \| \| \| \|


membrane proteins have a hydrophobic region that can only be
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constructed in the interior of a lipid bilayer. \| \| \| \| \| \| \|




Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, \| \| \| \| \| \| \|


mainly secreted by endothelial cells. It acts by binding to an
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extracellular ligand-binding site on ETA and ETB receptors. \| \| \| \| \| \| \| \|


Because the ETA and ETB receptors are integral membrane
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proteins, they are translated at the rough endoplasmic reticulum
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(ER). Which of the following statements describes the orientation
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of the receptor polypeptides in the ER membrane? - CORRECT
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ANSWERS ✔✔The receptor polypeptides are orientated with the
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extracellular ligand-binding site facing the ER lumen (interior). \| \| \| \| \| \| \|




The endoplasmic reticulum plays a critical role in protein
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synthesis. It has other functions too. Is the following statement
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TRUE or FALSE? \| \|