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UTMB ADVANCED PATHOPHYSIOLOGY
5355 EXAM 3 2025 UPDATED ACTUAL
EXAM WITH CORRECT SOLUTIONS.
Biogenic Amine Theory linked to depression - correct answer-
Deficiency of neurotransmitters in brain of norepinephrine,
dopamine, and/or serotonin. Particularly, a decrease in receptor
binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression -
correct answer- A deficiency of monoamine neurotransmitters
at neuronal synapses.
Antidepressants increase - correct answer- Neuronal synaptic
levels of monoamine neurotransmitters.
if you have more receptors than neurotransmitters - correct
answer- Neurotransmitters do not have time to re-charge thus,
they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation -
correct answer- HPA system dysregulation with excessive
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glucocorticoid secretion is found in a large percentage of
people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --
, with decreased levels of - - correct answer- Amyloid B,
neurofibrillary tangles, acetylcholine these disrupt impulse
transmission
neurofibrillary tangles - correct answer- are a deformation of the
structure that carries nutrients to neurons of the brain.
Decreased levels of choline acetyl transferase and
acetylcholine is associated with - correct answer- Memory loss
Most common cause of dementia - correct answer- Alzheimer's
disease fatal 5-10 years
Characteristics of Alzheimer's - correct answer- Loss of
memory, language , inability to learn new things, dysfunction,
delusions, cannot perform ADLs, majorly effects social life
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Parkinson's Disease is - correct answer- Chronic motor
progressive neuro-degenerative known as a shaking palsy
Parkinson's disease is associated with - correct answer- basal
ganglia dysfunction and atrophy of neurons in the substantia
nigra that produce dopamine;
Characteristics of Parkinson's disease - correct answer-
Tremors at rest, rigidity, bradykinesia, muscular rigidity and
postural abnormalities.
2 Main Categories of CVA - correct answer- Hemorrhagic and
Ischemic
Hemorrhagic CVA - correct answer- Blood produces
inflammatory reaction, swelling, displaces brain tissue and
increases ICP
2 types of hemorrhagic stroke - correct answer- Intracerebral
and subarachnoid
UTMB ADVANCED PATHOPHYSIOLOGY
5355 EXAM 3 2025 UPDATED ACTUAL
EXAM WITH CORRECT SOLUTIONS.
Biogenic Amine Theory linked to depression - correct answer-
Deficiency of neurotransmitters in brain of norepinephrine,
dopamine, and/or serotonin. Particularly, a decrease in receptor
binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression -
correct answer- A deficiency of monoamine neurotransmitters
at neuronal synapses.
Antidepressants increase - correct answer- Neuronal synaptic
levels of monoamine neurotransmitters.
if you have more receptors than neurotransmitters - correct
answer- Neurotransmitters do not have time to re-charge thus,
they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation -
correct answer- HPA system dysregulation with excessive
,2 | Page
glucocorticoid secretion is found in a large percentage of
people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --
, with decreased levels of - - correct answer- Amyloid B,
neurofibrillary tangles, acetylcholine these disrupt impulse
transmission
neurofibrillary tangles - correct answer- are a deformation of the
structure that carries nutrients to neurons of the brain.
Decreased levels of choline acetyl transferase and
acetylcholine is associated with - correct answer- Memory loss
Most common cause of dementia - correct answer- Alzheimer's
disease fatal 5-10 years
Characteristics of Alzheimer's - correct answer- Loss of
memory, language , inability to learn new things, dysfunction,
delusions, cannot perform ADLs, majorly effects social life
, 3 | Page
Parkinson's Disease is - correct answer- Chronic motor
progressive neuro-degenerative known as a shaking palsy
Parkinson's disease is associated with - correct answer- basal
ganglia dysfunction and atrophy of neurons in the substantia
nigra that produce dopamine;
Characteristics of Parkinson's disease - correct answer-
Tremors at rest, rigidity, bradykinesia, muscular rigidity and
postural abnormalities.
2 Main Categories of CVA - correct answer- Hemorrhagic and
Ischemic
Hemorrhagic CVA - correct answer- Blood produces
inflammatory reaction, swelling, displaces brain tissue and
increases ICP
2 types of hemorrhagic stroke - correct answer- Intracerebral
and subarachnoid
