PN 1005 PHARMACOLOGY
MIDTERM EXAM 2025 QUESTIONS
AND ANSWERS
half-life - ....ANSWER ...-The time it takes for the amount of drug in the
body to decrease to one half the peak level ot previously achieved
Absorption - ....ANSWER ...-is what happens to a drug from the time it
enters the body until it enters the circulating fluid
active transport - ....ANSWER ...-Energy-requiring process that moves
material across a cell membrane against a concentration difference
chemotherapeutic agents - ....ANSWER ...-synthetic chemicals used to
interfere with the functioning of foreign cell populations; this term is frequently
used to refer to the drug therapy of neoplasms, but it also refers to drug therapy
affecting any foreign cell
critical concentration - ....ANSWER ...-the concentration a drug must reach
in the tissues that respond to the particular drug to cause the desired therapeutic
effect
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 1
, Distribution - ....ANSWER ...-movement of a drug to body tissues; the
places where a drug may be distributed depend on the drug's solubility, perfusion
of the area, cardiac output, and binding of the drug to plasma proteins
enzyme induction - ....ANSWER ...-process by which the presence of a
chemical that is biotransformed by a particular enzyme system in the liver causes
increased activity of that enzyme system
Excretion - ....ANSWER ...-removal of a drug from the body; primarily
occurs in the kidneys, but can also occur through the skin, lungs, bile, or feces
first-pass - ....ANSWER ...-phenomenon in which drugs given orally are
carried directly to the liver after absorption where they may be largely inactivated
by the liver enzymes before they can enter the general circulation
glomerular filtration - ....ANSWER ...-the passage of water and water-soluble
components from the plasma into the renal tubule
hepatic microsomal system - ....ANSWER ...-liver enzymes tightly packed
together in the hepatic intracellular structure, responsible for the biotransformation
of chemicals, including drugs
loading dose - ....ANSWER ...-use of a higher dose than what is usually used
for treatment to allow the drug to reach the critical concentration sooner
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 2
MIDTERM EXAM 2025 QUESTIONS
AND ANSWERS
half-life - ....ANSWER ...-The time it takes for the amount of drug in the
body to decrease to one half the peak level ot previously achieved
Absorption - ....ANSWER ...-is what happens to a drug from the time it
enters the body until it enters the circulating fluid
active transport - ....ANSWER ...-Energy-requiring process that moves
material across a cell membrane against a concentration difference
chemotherapeutic agents - ....ANSWER ...-synthetic chemicals used to
interfere with the functioning of foreign cell populations; this term is frequently
used to refer to the drug therapy of neoplasms, but it also refers to drug therapy
affecting any foreign cell
critical concentration - ....ANSWER ...-the concentration a drug must reach
in the tissues that respond to the particular drug to cause the desired therapeutic
effect
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 1
, Distribution - ....ANSWER ...-movement of a drug to body tissues; the
places where a drug may be distributed depend on the drug's solubility, perfusion
of the area, cardiac output, and binding of the drug to plasma proteins
enzyme induction - ....ANSWER ...-process by which the presence of a
chemical that is biotransformed by a particular enzyme system in the liver causes
increased activity of that enzyme system
Excretion - ....ANSWER ...-removal of a drug from the body; primarily
occurs in the kidneys, but can also occur through the skin, lungs, bile, or feces
first-pass - ....ANSWER ...-phenomenon in which drugs given orally are
carried directly to the liver after absorption where they may be largely inactivated
by the liver enzymes before they can enter the general circulation
glomerular filtration - ....ANSWER ...-the passage of water and water-soluble
components from the plasma into the renal tubule
hepatic microsomal system - ....ANSWER ...-liver enzymes tightly packed
together in the hepatic intracellular structure, responsible for the biotransformation
of chemicals, including drugs
loading dose - ....ANSWER ...-use of a higher dose than what is usually used
for treatment to allow the drug to reach the critical concentration sooner
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 2
