PRACTICE EXAM QUESTIONS
WITH CORRECT DETAILED
ANSWERS | ALREADY GRADED
A+<RECENT VERSION>
1) Apoptosis - answer a programmed cell death that is regulated or
programmed. Cellular self-destruction for elimination or unwanted cell
populations
2) necrosis - answer rapid loss of the plasma membrane structure,
organelle swelling, mitochondria dysfunction
3) what is the #1 cause of cellular injury leading to necrosis (especially the
kidney and heart) - answer hypoxia
4) what is the #1 cause of hypoxia? - answer ischemia
5) main component of a cell - answer nucleus
6) what does the nucleus contain? - answer nucleolus
,7) what is the nucleolus composed of? - answer rna, most of cellular dna,
dna binding proteins, and histones
8) why are histone important? - answer histones bind to dna and fold it
into chromosomes (chromatin) which is essential for cell division
9) what are ribosomes? - answer rna-protein complexes (nucleoproteins)
that are synthesized in the nucleolus and secreted into the cytoplasm
through pores in the nuclear envelope called nuclear pore complexes
(npcs)
10) where can ribosomes be found? - answer cytoplasm and rough
er
11) what are ribosomes chief function? - answer provides sits for
cellular protein synthesis
12) what is the golgi apparatus (complex)? - answer a network of
flatten, smooth membranes and vesicles frequently located near the
nucleus of the cell
13) what does the golgi apparatus do? - answer takes proteins from
the er and processes/packages them into small membrane-bound vesicles
called "secretory vesicles, and refines and directs traffic in the cell
14) what are lysosomes and what do they do? - answer maintain
cellular health by removal of toxic cellular components, removal of
useless organelles, termination of signal transduction, and signals cellular
adaption
,15) how does aging affect lysosomes? - answer leads to progressive
loss of lysosomal efficiency which declines the regenerative capacity of
organs and tissue
16) what functions do lysosomal components integrate? - answer
nutrient abundance, energy levels, and cell stressors and will translate
them into instructions that regulate cellular metabolism toward either
proliferation or inactivity
17) what is mitochondria responsible for? - answer cellular
respiration, cellular metabolism , and energy production
18) what does the inner membrane of mitochondria contain? -
answer enzymes of the respiratory chain and are essential to the
process of oxidative phosphorylation that generates most of the cell's atp
19) the mitochondrial matrix contains what kind of pathways (1),
involve what two things (2), and metabolizes what three things (3)? -
answer 1- metabolic
2- urea and heme synthesis
3- carbs, proteins, and lipids
20) what can accumulate intracellularly caused by stresses form
metabolic dearangements? - answer carbs, proteins, and lipids
21) what is physiologic atrophy? - answer occurs in early
development. Ex: thymus glad during childhood
22) what is pathologic atrophy? - answer occurs as a result of
decreases in workload, use, pressure, blood supply, nutrition, and
hormonal stimulation.
, 23) Ex: shrinking of gonads in an adolescent pt in response to
decreased hormonal stimulation. And an pt immobilized in bed for a
prolonged time
24) what is hypertrophy? - answer increase in cell size
25) example of beneficial physiologic hypertrophy? - answer
hypertrophy of myocardial cells from endurance training
26) example of pathologic hypertrophy - answer cardiomegaly in a
hypertensive patient
27) what is hyperplasia? - answer increase in the number of cells
28) example of compensatory hyperplasia? - answer regeneration of
the liver
29) example of pathological hyperplasia - answer endometrial
tissue
30) example of hormonal hyperplasia - answer enlargement of the
uterus during pregnancy
31) what is metaplasia? - answer replacement of the cells
32) example of metaplasia - answer normal columnar ciliated
epithelial cells of the bronchial lining being replaced by squamous cells.
Can be reversed if irritant stopped