NCLEX : GI EXAM 2025 QUESTIONS
AND ANSWERS
A 74-year-old female patient with gastroesophageal reflux disease (GERD) takes over-the-
counter medications. For which medication, if taken long-term, should the nurse teach about
an increased risk of fractures?
a. Sucralfate (Carafate)
b. Cimetidine (Tagamet)
c. Omeprazole (Prilosec)
d. Metoclopramide (Reglan) - ANS c. Omeprazole (Prilosec)
There is a potential link between proton pump inhibitors (PPIs) (e.g., omeprazole) use and bone
metabolism. Long-term use or high doses of PPIs may increase the risk of fractures of the hip,
wrist, and spine. Lower doses or shorter duration of therapy should be considered.
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,Following administration of a dose of metoclopramide (Reglan) to the patient, the nurse
determines that the medication has been effective when what is noted?
a. Decreased blood pressure
b. Absence of muscle tremors
c. Relief of nausea and vomiting
d. No further episodes of diarrhea - ANS c. Relief of nausea and vomiting
Metoclopramide is classified as a prokinetic and antiemetic medication. If it is effective, the
patient's nausea and vomiting should resolve. Metoclopramide does not affect blood pressure,
muscle tremors, or diarrhea.
The patient receiving chemotherapy rings the call bell and reports the onset of nausea. The
nurse should prepare an as-needed dose of which medication?
a. Morphine sulfate
b. Zolpidem (Ambien)
c. Ondansetron (Zofran)
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, d. Dexamethasone (Decadron) - ANS c. Ondansetron (Zofran)*
Ondansetron is a 5-HT3 receptor antagonist antiemetic that is especially effective in reducing
cancer chemotherapy-induced nausea and vomiting. Morphine sulfate may cause nausea and
vomiting. Zolpidem does not relieve nausea and vomiting. Dexamethasone is usually used in
combination with ondansetron for acute and chemotherapy-induced emesis.
The patient who is admitted with a diagnosis of diverticulitis and a history of irritable bowel
disease and gastroesophageal reflux disease (GERD) has received a dose of Mylanta 30 mL PO.
The nurse should evaluate its effectiveness by questioning the patient as to whether which
symptom has been resolved?
a. Diarrhea
b. Heartburn
c. Constipation
d. Lower abdominal pain - ANS b. Heartburn
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AND ANSWERS
A 74-year-old female patient with gastroesophageal reflux disease (GERD) takes over-the-
counter medications. For which medication, if taken long-term, should the nurse teach about
an increased risk of fractures?
a. Sucralfate (Carafate)
b. Cimetidine (Tagamet)
c. Omeprazole (Prilosec)
d. Metoclopramide (Reglan) - ANS c. Omeprazole (Prilosec)
There is a potential link between proton pump inhibitors (PPIs) (e.g., omeprazole) use and bone
metabolism. Long-term use or high doses of PPIs may increase the risk of fractures of the hip,
wrist, and spine. Lower doses or shorter duration of therapy should be considered.
Copyright ©2025 BRIGHTSTARS ALL RIGHTS RESERVED 1
,Following administration of a dose of metoclopramide (Reglan) to the patient, the nurse
determines that the medication has been effective when what is noted?
a. Decreased blood pressure
b. Absence of muscle tremors
c. Relief of nausea and vomiting
d. No further episodes of diarrhea - ANS c. Relief of nausea and vomiting
Metoclopramide is classified as a prokinetic and antiemetic medication. If it is effective, the
patient's nausea and vomiting should resolve. Metoclopramide does not affect blood pressure,
muscle tremors, or diarrhea.
The patient receiving chemotherapy rings the call bell and reports the onset of nausea. The
nurse should prepare an as-needed dose of which medication?
a. Morphine sulfate
b. Zolpidem (Ambien)
c. Ondansetron (Zofran)
Copyright ©2025 BRIGHTSTARS ALL RIGHTS RESERVED 2
, d. Dexamethasone (Decadron) - ANS c. Ondansetron (Zofran)*
Ondansetron is a 5-HT3 receptor antagonist antiemetic that is especially effective in reducing
cancer chemotherapy-induced nausea and vomiting. Morphine sulfate may cause nausea and
vomiting. Zolpidem does not relieve nausea and vomiting. Dexamethasone is usually used in
combination with ondansetron for acute and chemotherapy-induced emesis.
The patient who is admitted with a diagnosis of diverticulitis and a history of irritable bowel
disease and gastroesophageal reflux disease (GERD) has received a dose of Mylanta 30 mL PO.
The nurse should evaluate its effectiveness by questioning the patient as to whether which
symptom has been resolved?
a. Diarrhea
b. Heartburn
c. Constipation
d. Lower abdominal pain - ANS b. Heartburn
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