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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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Chapter1, The Foundation ofPharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
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paroxetine hydrochloride. What is the expected effect for this prescription?
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A. Curative effect on symptoms vb vb vb
B. Systemic effect on symptoms vb vb vb
C. Local effect on symptoms vb vb vb
D. Parenteral effect on symptoms vb vb vb
ANS: B v b
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
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bloodstream to their sites of action in various body tissues, and eventually eliminated from the
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body. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
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will control the symptoms but not cure the disorder. Drugs with local effects,such as sunscreen
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and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not
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administered parenterally. Parenteral agents are administered subcutaneously,
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intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 vb vb
NAT: v b Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP:
vb Chapter: 1: The Foundation of Pharmacology: Quality and Safety vb vb vb vb vb vb vb vb
KEY: v b Integrated Process: NursingProcess vb vb vb
BLM: v Cognitive Level: Understand
b NOT: Multiple Choice vb vb v b vb
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mR icAalDlyEm
SoBdOifOieSd.TWhaOtM
.C is another name for this type of
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medication?
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A. Synthetic drug vb
B. Semisynthetic drug vb
C. Biotechnology drug vb
D. Prototype drug vb
ANS: B v b
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
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have been chemically modified. Synthetic drugs are morestandardized in their chemical
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characteristics, more consistent in their effects, and less likely to produce allergic reactions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining genes into hybrid
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molecules that can be inserted into living organisms. Prototype drugs are the first drugof a
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particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 vb vb vb
NAT: v b Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP:
vb Chapter: 1: The Foundation of Pharmacology: Quality and Safety vb vb vb vb vb vb vb vb
KEY: v b Integrated Process: NursingProcess vb vb vb
BLM: v Cognitive Level: Understand
b NOT: Multiple Choice vb vb v b vb
3. Which classification applies to morphine? vb vb vb vb
A. Central nervous system depressant vb vb vb
B. Central nervous system stimulant vb vb vb
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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