MN605 ADVANCED PHARMACOLOGY
FINAL EXAM QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS) PLUS
RATIONALES 2025
1. Which class of drugs is considered first-line treatment for generalized
anxiety disorder (GAD)?
A. Beta-blockers
B. SSRIs
C. Benzodiazepines
D. MAOIs
SSRIs (e.g., sertraline, paroxetine) are first-line due to their favorable
safety profile and efficacy in treating GAD.
2. Which of the following medications is most appropriate for treating
neuropathic pain?
A. Acetaminophen
B. Gabapentin
, C. Ibuprofen
D. Oxycodone
Gabapentin is commonly used for neuropathic pain due to its effects
on calcium channels in the nervous system.
3. What is the mechanism of action of beta-lactam antibiotics?
A. Inhibit DNA gyrase
B. Inhibit cell wall synthesis
C. Inhibit protein synthesis
D. Inhibit folic acid synthesis
Beta-lactam antibiotics inhibit bacterial cell wall synthesis by binding
to penicillin-binding proteins.
4. Which medication is contraindicated in pregnancy due to
teratogenicity?
A. Amoxicillin
B. Isotretinoin
C. Acetaminophen
D. Penicillin
Isotretinoin is highly teratogenic and is contraindicated in pregnancy.
5. Which of the following drugs requires monitoring of INR levels?
A. Rivaroxaban
B. Warfarin
C. Dabigatran
D. Apixaban
, Warfarin requires regular INR monitoring due to its narrow
therapeutic index.
6. What is a common side effect of ACE inhibitors?
A. Tachycardia
B. Dry cough
C. Hypernatremia
D. Bradycardia
ACE inhibitors often cause dry cough due to bradykinin accumulation.
7. Which of the following medications should be avoided in patients with
asthma?
A. Non-selective beta-blockers
B. Leukotriene antagonists
C. Inhaled corticosteroids
D. Long-acting beta agonists
Non-selective beta-blockers may cause bronchospasm, worsening
asthma symptoms.
8. Which diabetic medication promotes weight loss?
A. Sulfonylureas
B. GLP-1 receptor agonists
C. Insulin
D. Thiazolidinediones
GLP-1 receptor agonists (e.g., liraglutide) promote weight loss and
improve glycemic control.
, 9. Which antidepressant is least likely to cause sexual dysfunction?
A. Fluoxetine
B. Sertraline
C. Bupropion
D. Paroxetine
Bupropion is associated with a lower incidence of sexual side effects.
10. Which lab test is necessary before initiating statin therapy?
A. Hemoglobin A1C
B. Liver function tests
C. TSH
D. Hematocrit
Statins can cause hepatotoxicity, so baseline liver function tests are
essential.
11. Which antihypertensive is preferred in diabetic patients with
proteinuria?
A. Beta-blockers
B. Calcium channel blockers
C. ACE inhibitors
D. Thiazide diuretics
ACE inhibitors protect renal function and reduce proteinuria in
diabetics.
12. Which medication is a dopamine agonist used to treat
Parkinson’s disease?
FINAL EXAM QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS) PLUS
RATIONALES 2025
1. Which class of drugs is considered first-line treatment for generalized
anxiety disorder (GAD)?
A. Beta-blockers
B. SSRIs
C. Benzodiazepines
D. MAOIs
SSRIs (e.g., sertraline, paroxetine) are first-line due to their favorable
safety profile and efficacy in treating GAD.
2. Which of the following medications is most appropriate for treating
neuropathic pain?
A. Acetaminophen
B. Gabapentin
, C. Ibuprofen
D. Oxycodone
Gabapentin is commonly used for neuropathic pain due to its effects
on calcium channels in the nervous system.
3. What is the mechanism of action of beta-lactam antibiotics?
A. Inhibit DNA gyrase
B. Inhibit cell wall synthesis
C. Inhibit protein synthesis
D. Inhibit folic acid synthesis
Beta-lactam antibiotics inhibit bacterial cell wall synthesis by binding
to penicillin-binding proteins.
4. Which medication is contraindicated in pregnancy due to
teratogenicity?
A. Amoxicillin
B. Isotretinoin
C. Acetaminophen
D. Penicillin
Isotretinoin is highly teratogenic and is contraindicated in pregnancy.
5. Which of the following drugs requires monitoring of INR levels?
A. Rivaroxaban
B. Warfarin
C. Dabigatran
D. Apixaban
, Warfarin requires regular INR monitoring due to its narrow
therapeutic index.
6. What is a common side effect of ACE inhibitors?
A. Tachycardia
B. Dry cough
C. Hypernatremia
D. Bradycardia
ACE inhibitors often cause dry cough due to bradykinin accumulation.
7. Which of the following medications should be avoided in patients with
asthma?
A. Non-selective beta-blockers
B. Leukotriene antagonists
C. Inhaled corticosteroids
D. Long-acting beta agonists
Non-selective beta-blockers may cause bronchospasm, worsening
asthma symptoms.
8. Which diabetic medication promotes weight loss?
A. Sulfonylureas
B. GLP-1 receptor agonists
C. Insulin
D. Thiazolidinediones
GLP-1 receptor agonists (e.g., liraglutide) promote weight loss and
improve glycemic control.
, 9. Which antidepressant is least likely to cause sexual dysfunction?
A. Fluoxetine
B. Sertraline
C. Bupropion
D. Paroxetine
Bupropion is associated with a lower incidence of sexual side effects.
10. Which lab test is necessary before initiating statin therapy?
A. Hemoglobin A1C
B. Liver function tests
C. TSH
D. Hematocrit
Statins can cause hepatotoxicity, so baseline liver function tests are
essential.
11. Which antihypertensive is preferred in diabetic patients with
proteinuria?
A. Beta-blockers
B. Calcium channel blockers
C. ACE inhibitors
D. Thiazide diuretics
ACE inhibitors protect renal function and reduce proteinuria in
diabetics.
12. Which medication is a dopamine agonist used to treat
Parkinson’s disease?
