MSN 571 PHARMACOLOGY MIDTERM (CARDIOLOGY)
What is the maximum half-life elimination of warfarin (coumadin) - Answers - 60 hours
The brand name for hydralazine - Answers - Apresoline
The side effect profile of angiotensin receptor blockers (ARBS) is similar to the side
effecs of: - Answers - Angiotensin-converting enzymes (ACE) inhibitors
An example of a cardio selective beta-blocker used in the treatment of heart failure is: -
Answers - metoprolol (Lopressor)
Aliskiren (Tekturna) , used in the treatment of essential hypertension, is classified as an
- Answers - direct renin inhibitor
Baseline and periodic monitoring for patients receiving hydralazine (Apresoline) should
include serum - Answers - CBC
Avoid concomitant use of oral digoxin (Lanoxin) and - Answers - Famotidine (pepcid)
The negative inotropic activity of nifedipine (Adalat CC ) that leads to an exacerbation of
heart failure may be further pronounced if combined with: - Answers - beta-blockers
Ranolazine (Ranexa) is indicatd in the treatment of: - Answers - chronic angina
A disadvantage of vitamin K antagonist for anticoagulation is their: - Answers -
numerous medication interactions
Trimterene (Dyrenium), a diuretic, should not be used in the presence of: - Answers -
anuria
Negative intropes are indicated for patients diagnosed with: - Answers - atrial
fibrillation
Dabigatron (Pradaxa), an anticoagulant, is also classified as a: - Answers - direct
thrombin inhibitor
Which beta-blocker is highly variable in bioavailability, has a shorter plasma half-life, is
mostly lipid-soluble, and is almost completely absorbed by the small intestine -
Answers - Metoprolol (Lopressor)
The peak effect of enalapril (Vasotec), an angiotensin-converting enzyme (ACE)
inhibitor, occurs in: - Answers - 5 hours
, Non-dihydropyridine calcium channel blockers (i.e. verapamil) may be safely used in
patients with: - Answers - chronic stable angina
Bile acid sequestrants such as colesevelem (Welchol): - Answers - Bind to bile acids
and excrete them in feces, forcing the liver to use cholesterol to produce more bile
acids.
Patients who are started on olmesartan (Benicar) should be advised to report: -
Answers - diarrhea and weight loss
An angiotensin II receptor blocker (ARB) that is indicated for the treatment of
hypertension in children younger than 6 years old is: - Answers - candesartan
(Atacand)
Increased adverse events are likely with the concomitant use of angiotensin-converting
enzyme (ACE) inhibitors such as ramipril (Altace) and: - Answers - Irbesartan (Avapro)
Ranolazine (Ranexa) exerts antianginal and anti-ischemic effects by: - Answers -
reducing sodium concentrations and calcium influx, thus decreasing oxygen
consumption
Reduced doses of lovastatin (Mevacor) are recommended when used concomitantly
with: - Answers - verapamil (Calan)
A common side effect of angiotensin II receptor blockers (ARBs) such as candesartan
(Atacand) is: - Answers - hyperkalemia
Spironolactone (Aldactone) is highly protein bound and has a duration of: - Answers -
48 hours
Acetaminophen ( Tylenol) use in infants and children is: - Answers - calculated at 10-
15 mg/kg/dose with a maximum of 4g/24 hours
An dverse reaction to angiotensen receptor blockers (ARBS) used in the treatment of
hypertension is: - Answers - angioedema
A common side effect of cardioselective beta-blockers such as labetolol (Trandate) is: -
Answers - shortness of breath
An example of a dihydropyridine calcium channel blocker is: - Answers - amlodipine
(Norvasc)
Which medication is considered a cholesterol absorption inhibitor? - Answers -
Ezetimibe
The onset of anticoagulation action for warfarin (coumadin) is: - Answers - 24-72 hours
What is the maximum half-life elimination of warfarin (coumadin) - Answers - 60 hours
The brand name for hydralazine - Answers - Apresoline
The side effect profile of angiotensin receptor blockers (ARBS) is similar to the side
effecs of: - Answers - Angiotensin-converting enzymes (ACE) inhibitors
An example of a cardio selective beta-blocker used in the treatment of heart failure is: -
Answers - metoprolol (Lopressor)
Aliskiren (Tekturna) , used in the treatment of essential hypertension, is classified as an
- Answers - direct renin inhibitor
Baseline and periodic monitoring for patients receiving hydralazine (Apresoline) should
include serum - Answers - CBC
Avoid concomitant use of oral digoxin (Lanoxin) and - Answers - Famotidine (pepcid)
The negative inotropic activity of nifedipine (Adalat CC ) that leads to an exacerbation of
heart failure may be further pronounced if combined with: - Answers - beta-blockers
Ranolazine (Ranexa) is indicatd in the treatment of: - Answers - chronic angina
A disadvantage of vitamin K antagonist for anticoagulation is their: - Answers -
numerous medication interactions
Trimterene (Dyrenium), a diuretic, should not be used in the presence of: - Answers -
anuria
Negative intropes are indicated for patients diagnosed with: - Answers - atrial
fibrillation
Dabigatron (Pradaxa), an anticoagulant, is also classified as a: - Answers - direct
thrombin inhibitor
Which beta-blocker is highly variable in bioavailability, has a shorter plasma half-life, is
mostly lipid-soluble, and is almost completely absorbed by the small intestine -
Answers - Metoprolol (Lopressor)
The peak effect of enalapril (Vasotec), an angiotensin-converting enzyme (ACE)
inhibitor, occurs in: - Answers - 5 hours
, Non-dihydropyridine calcium channel blockers (i.e. verapamil) may be safely used in
patients with: - Answers - chronic stable angina
Bile acid sequestrants such as colesevelem (Welchol): - Answers - Bind to bile acids
and excrete them in feces, forcing the liver to use cholesterol to produce more bile
acids.
Patients who are started on olmesartan (Benicar) should be advised to report: -
Answers - diarrhea and weight loss
An angiotensin II receptor blocker (ARB) that is indicated for the treatment of
hypertension in children younger than 6 years old is: - Answers - candesartan
(Atacand)
Increased adverse events are likely with the concomitant use of angiotensin-converting
enzyme (ACE) inhibitors such as ramipril (Altace) and: - Answers - Irbesartan (Avapro)
Ranolazine (Ranexa) exerts antianginal and anti-ischemic effects by: - Answers -
reducing sodium concentrations and calcium influx, thus decreasing oxygen
consumption
Reduced doses of lovastatin (Mevacor) are recommended when used concomitantly
with: - Answers - verapamil (Calan)
A common side effect of angiotensin II receptor blockers (ARBs) such as candesartan
(Atacand) is: - Answers - hyperkalemia
Spironolactone (Aldactone) is highly protein bound and has a duration of: - Answers -
48 hours
Acetaminophen ( Tylenol) use in infants and children is: - Answers - calculated at 10-
15 mg/kg/dose with a maximum of 4g/24 hours
An dverse reaction to angiotensen receptor blockers (ARBS) used in the treatment of
hypertension is: - Answers - angioedema
A common side effect of cardioselective beta-blockers such as labetolol (Trandate) is: -
Answers - shortness of breath
An example of a dihydropyridine calcium channel blocker is: - Answers - amlodipine
(Norvasc)
Which medication is considered a cholesterol absorption inhibitor? - Answers -
Ezetimibe
The onset of anticoagulation action for warfarin (coumadin) is: - Answers - 24-72 hours
