N4431 UTA Pediatric Exam 3 questions with
verified answers
Anemia Ans✓✓✓RBC & Hgb lower than normal
Causes of anemia:
1) Į production or loss & destruction of RBCS related to lack of dietary
intake of nutrients needed to produce cells
2) Alterations in cell structure
3) Malfunctioning tissue
4) Toxin exposure (lead)
5) Adverse reaction to med (aplastic anemia- not making RBCS)
Aplastic Anemia Ans✓✓✓Pancytopenia:
• all three blood cellular components low or absent
• these cellular components include red blood cells, white blood cells,
and platelets
• complete bone marrow suppression or failure
,• rich red marrow replaces with yellow fatty substance
• congenital (autosomal recessive) or acquired (bone marrow
destruction)
Causes of Acquired Aplastic Anemia:
• autoimmune response
• infection
• chemical exposure
• pharmacological agents
• radiation
Aplastic Anemia Manifestations Ans✓✓✓Manifestations Associated
with Congenital:
• skeletal defects and genitourinary deformities
• sensory dysfunctions
• cafe au lair spots
• cardiac defects
• delayed growth and short stature
• microcephaly and intellectual disability
Manifestations Associated with Acquired:
• excessive fatigue and weakness with behavioral changes
• recurrent infections and febrile episodes
• petechia, bruising, epistaxis, and excessive bleeding
, Aplastic Anemia Treatments Ans✓✓✓Bone Marrow or Stem-Cell
Transplantation:
• rejection
• failure to implant
• immune system suppression using antithymocyte globulin or globulin
and cyclosporin after transplant
Androgen Therapy:
• induces puberty in males
• patient and family education
Physical and occupational therapy for sensory dysfunctions
Promote growth and development
Neutropenic precautions to prevent infection
Beta-Thalassemia (Cooley's Anemia) Ans✓✓✓• abnormal Hgb beta
chains lead to rapid RBC destruction
• autosomal recessive condition
• ethnically linked
• hemolytic anemia with bone marrow hyperplasia due to erythropoiesis
verified answers
Anemia Ans✓✓✓RBC & Hgb lower than normal
Causes of anemia:
1) Į production or loss & destruction of RBCS related to lack of dietary
intake of nutrients needed to produce cells
2) Alterations in cell structure
3) Malfunctioning tissue
4) Toxin exposure (lead)
5) Adverse reaction to med (aplastic anemia- not making RBCS)
Aplastic Anemia Ans✓✓✓Pancytopenia:
• all three blood cellular components low or absent
• these cellular components include red blood cells, white blood cells,
and platelets
• complete bone marrow suppression or failure
,• rich red marrow replaces with yellow fatty substance
• congenital (autosomal recessive) or acquired (bone marrow
destruction)
Causes of Acquired Aplastic Anemia:
• autoimmune response
• infection
• chemical exposure
• pharmacological agents
• radiation
Aplastic Anemia Manifestations Ans✓✓✓Manifestations Associated
with Congenital:
• skeletal defects and genitourinary deformities
• sensory dysfunctions
• cafe au lair spots
• cardiac defects
• delayed growth and short stature
• microcephaly and intellectual disability
Manifestations Associated with Acquired:
• excessive fatigue and weakness with behavioral changes
• recurrent infections and febrile episodes
• petechia, bruising, epistaxis, and excessive bleeding
, Aplastic Anemia Treatments Ans✓✓✓Bone Marrow or Stem-Cell
Transplantation:
• rejection
• failure to implant
• immune system suppression using antithymocyte globulin or globulin
and cyclosporin after transplant
Androgen Therapy:
• induces puberty in males
• patient and family education
Physical and occupational therapy for sensory dysfunctions
Promote growth and development
Neutropenic precautions to prevent infection
Beta-Thalassemia (Cooley's Anemia) Ans✓✓✓• abnormal Hgb beta
chains lead to rapid RBC destruction
• autosomal recessive condition
• ethnically linked
• hemolytic anemia with bone marrow hyperplasia due to erythropoiesis
