NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
1. Antacids
-Nursing considerations:
(calcium
-Work fast but not for long
carbonate,
-Not practical to give 1-2 hours around the clock and only taken PO
tums)
-Those with renal failure - give calcium carbonate antacids as it can
help to bind phosphate
-Drug interactions:
-Toxicity from salts all preclude regular/acute care use
-Drug interactions with fluoroquinolones, tetracyclines, some
antiretrovirals
-Contraindications:
-Allergy
-Renal failure or electrolyte disturbances - Do not take magnesium
antacids can accumulate in renal failure
-ADR
-Constipation
2. calcium carbonateWhat type of antacid do we give those with renal failure because it
binds to
phosphae
3. Magnesiu What type of antacid do we AVOID giving to those with renal failure
m ot electrolyte disturbances because it accumulates in the kidneys and
antacids causes worsening renal failure?
-Toxicity from salts all preclude regular/acute care use
4. Antacids: Drug -Drug interactions with fluoroquinolones, tetracyclines, some
In- teractions antiretrovirals
5. constipation What is the one ADR of antacids?
6. H2 blockers famotidine)
("ti- dine"-
ranitidine,
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-MOA: reduce acid
secretion through
histamine2 blockade
-ADRs:
-Overall very few
-Can increase
anticholinergic burden
(CNS ADRs in elderly
patients include
confusion/disorientation
)
-Increased risk of
pneumonia
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-Increased risk of C. diflcile
-B12 deficiency anemia with long term use
7. H2 blockers MOA - reduce acid secretion through histamine2 blockade
8. H2 blocker ADR - Can increase anticholinergic burden (CNS ADRs in elderly patients
include
confusion/disorientation)
-Increased risk of pneumonia
-Increased risk of C. diflcile
-B12 deficiency anemia with long term use
9. Proton pump in- -MOA: irreversibly bind to H+/K+ adenosine triphosphatase (ATPase)
hibitors - ("pra- enzyme
zole"- -IV, PO, long acting = most ettective acid suppressive therapy
rabeprazole, -Nursing considerations:
omeprazole, panto- - All PPIs begin to lose ettectiveness if exposed to gastric acid
directly
prazole -All oral PPI dosage forms even the "dissolving beads" retain an
sodium) enteric coating that are meant to remain intact until the small
intestine (site of most drug absorption)
-Always ensure that no dosage form of a PPI is crushed!
-ADRs:
-Very similar to H2 blockers (but this is like due to a greater eflcacy
seen - somewhat higher risk of acid suppression related ADRs)
-Pneumonia, C. diflcile, B12, calcium deficiency
-Osteoporosis: risk of wrist/hip/spine fractures in long-term use of
HIV con- trol
-Interactions:
-Raise stomach pH ’may reduce absorption of medications that
need acidic environments to absorbed
-Rilpivirine = antiretroviral drug that can have its ettects diminished
when administered with PPIs ’leads to loss
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-PPIs known to inhibit
"OAT3"
-Organic ion
transporter (needed
to excrete various
drugs via renal route)
Answers
1. Antacids
-Nursing considerations:
(calcium
-Work fast but not for long
carbonate,
-Not practical to give 1-2 hours around the clock and only taken PO
tums)
-Those with renal failure - give calcium carbonate antacids as it can
help to bind phosphate
-Drug interactions:
-Toxicity from salts all preclude regular/acute care use
-Drug interactions with fluoroquinolones, tetracyclines, some
antiretrovirals
-Contraindications:
-Allergy
-Renal failure or electrolyte disturbances - Do not take magnesium
antacids can accumulate in renal failure
-ADR
-Constipation
2. calcium carbonateWhat type of antacid do we give those with renal failure because it
binds to
phosphae
3. Magnesiu What type of antacid do we AVOID giving to those with renal failure
m ot electrolyte disturbances because it accumulates in the kidneys and
antacids causes worsening renal failure?
-Toxicity from salts all preclude regular/acute care use
4. Antacids: Drug -Drug interactions with fluoroquinolones, tetracyclines, some
In- teractions antiretrovirals
5. constipation What is the one ADR of antacids?
6. H2 blockers famotidine)
("ti- dine"-
ranitidine,
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-MOA: reduce acid
secretion through
histamine2 blockade
-ADRs:
-Overall very few
-Can increase
anticholinergic burden
(CNS ADRs in elderly
patients include
confusion/disorientation
)
-Increased risk of
pneumonia
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-Increased risk of C. diflcile
-B12 deficiency anemia with long term use
7. H2 blockers MOA - reduce acid secretion through histamine2 blockade
8. H2 blocker ADR - Can increase anticholinergic burden (CNS ADRs in elderly patients
include
confusion/disorientation)
-Increased risk of pneumonia
-Increased risk of C. diflcile
-B12 deficiency anemia with long term use
9. Proton pump in- -MOA: irreversibly bind to H+/K+ adenosine triphosphatase (ATPase)
hibitors - ("pra- enzyme
zole"- -IV, PO, long acting = most ettective acid suppressive therapy
rabeprazole, -Nursing considerations:
omeprazole, panto- - All PPIs begin to lose ettectiveness if exposed to gastric acid
directly
prazole -All oral PPI dosage forms even the "dissolving beads" retain an
sodium) enteric coating that are meant to remain intact until the small
intestine (site of most drug absorption)
-Always ensure that no dosage form of a PPI is crushed!
-ADRs:
-Very similar to H2 blockers (but this is like due to a greater eflcacy
seen - somewhat higher risk of acid suppression related ADRs)
-Pneumonia, C. diflcile, B12, calcium deficiency
-Osteoporosis: risk of wrist/hip/spine fractures in long-term use of
HIV con- trol
-Interactions:
-Raise stomach pH ’may reduce absorption of medications that
need acidic environments to absorbed
-Rilpivirine = antiretroviral drug that can have its ettects diminished
when administered with PPIs ’leads to loss
, NURS 2750 - Health And Healing Quiz 2 Pharm And Correct
Answers
-PPIs known to inhibit
"OAT3"
-Organic ion
transporter (needed
to excrete various
drugs via renal route)
