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NR 565 - advanced pharmacology midterm -
Chamberlain
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NR565- Advanced Pharm- Week 8 &... NR 565 - advanced pharmacology ... NR511 2025 |EXAM (M
77 terms 63 terms Teacher 99 terms
slj366 Preview lov3isblind Preview morris_munene6
During what trimester is a 1st trimester (fetus most at risk d/t rapid growth)
pregnant woman most at risk for
adverse drug reactions with
potential long term
consequences?
Recommendations of medications inappropriate for elderly (65
What is BEERS criteria?
and older), prescriber ultimately decides
What is the CYP450 liver enzyme system where medications are metabolized, can
(cytochrome P450) either be inducers or inhibitors and create drug-drug interactions
Speed up metabolism of drugs (drug is cleared faster), drug has
CYP450 inducers lesser effect (decrease blood levels of drug), elevate CYP450
enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
Barbituates, St John wort, Carbamazepine, rifampin, alcohol,
CYP450 inducer drug names
phenytoin, griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
"VISA credit card debt INHIBITS spending on designers like CK
CYP450 pneumonic
to look GQ"
Valproate, isoniazid, sulfonamides, amiodarone,
CYP450 inhibitors drug names
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during increase glomerular filtration rate leads to increase durg
pregnancy that impact excretion
pharmacodynamics and increase hepatic metabolism
pharmacokinetic properties of decrease tone and motility of bowel
drugs? increase drug absorption
Antiepileptic drugs, antimicrobials such as tetracyclines and
Examples of medications that
fluoroquinolones, vitamin A in large doses, some anticoagulants,
can be teratogenic
and hormonal medications such as diethylstilbestrol (DES).
, How is absorption of slow and erratic due to low blood flow in muscles first few days
intramuscular medications of life
different in neonates?
Why is absorption of medication delayed gastric emptying
in the stomach increased in
infancy?
glucocorticoids, discoloration of developing teeth with
Some medications that should
tetracyclines, and kernicterus with sulfonamides, levofloxacin
be avoided in the pediatric
(antibiotics)
patient?
aspirin (Severe intoxication from acute overdose)
dosage size and timing
route and technique of administration
what should be included in duration of treatment
medication administration drug storage
patient education? nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
What are some things that put presence of comorbidities
the elderly patient at higher risk use of drugs that have a low therapeutic index (e.g., digoxin)
for adverse drug reactions? increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
obtaining a thorough drug history that includes over-the-counter
medications
considering pharmacokinetic and pharmacodynamics changes
due to age
How can healthcare providers
monitoring the patient's clinical response and plasma drug levels
decrease likelihood of an
using the simplest regimen possible
elderly patient experiencing an
monitoring for drug-drug interactions and iatrogenic illness
adverse drug reaction?
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the
Beers list
simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
How can we promote
clearly labeling and dispensing easy-to-open containers
medication adherence with
developing daily reminders
elderly patients?
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be Need nitrate free interval so tolerance doesn't develop
taken no later than 4 PM?
NR 565 - advanced pharmacology midterm -
Chamberlain
Save
Students also studied
Flashcard sets Study guides
NR565- Advanced Pharm- Week 8 &... NR 565 - advanced pharmacology ... NR511 2025 |EXAM (M
77 terms 63 terms Teacher 99 terms
slj366 Preview lov3isblind Preview morris_munene6
During what trimester is a 1st trimester (fetus most at risk d/t rapid growth)
pregnant woman most at risk for
adverse drug reactions with
potential long term
consequences?
Recommendations of medications inappropriate for elderly (65
What is BEERS criteria?
and older), prescriber ultimately decides
What is the CYP450 liver enzyme system where medications are metabolized, can
(cytochrome P450) either be inducers or inhibitors and create drug-drug interactions
Speed up metabolism of drugs (drug is cleared faster), drug has
CYP450 inducers lesser effect (decrease blood levels of drug), elevate CYP450
enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
Barbituates, St John wort, Carbamazepine, rifampin, alcohol,
CYP450 inducer drug names
phenytoin, griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
"VISA credit card debt INHIBITS spending on designers like CK
CYP450 pneumonic
to look GQ"
Valproate, isoniazid, sulfonamides, amiodarone,
CYP450 inhibitors drug names
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during increase glomerular filtration rate leads to increase durg
pregnancy that impact excretion
pharmacodynamics and increase hepatic metabolism
pharmacokinetic properties of decrease tone and motility of bowel
drugs? increase drug absorption
Antiepileptic drugs, antimicrobials such as tetracyclines and
Examples of medications that
fluoroquinolones, vitamin A in large doses, some anticoagulants,
can be teratogenic
and hormonal medications such as diethylstilbestrol (DES).
, How is absorption of slow and erratic due to low blood flow in muscles first few days
intramuscular medications of life
different in neonates?
Why is absorption of medication delayed gastric emptying
in the stomach increased in
infancy?
glucocorticoids, discoloration of developing teeth with
Some medications that should
tetracyclines, and kernicterus with sulfonamides, levofloxacin
be avoided in the pediatric
(antibiotics)
patient?
aspirin (Severe intoxication from acute overdose)
dosage size and timing
route and technique of administration
what should be included in duration of treatment
medication administration drug storage
patient education? nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
What are some things that put presence of comorbidities
the elderly patient at higher risk use of drugs that have a low therapeutic index (e.g., digoxin)
for adverse drug reactions? increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
obtaining a thorough drug history that includes over-the-counter
medications
considering pharmacokinetic and pharmacodynamics changes
due to age
How can healthcare providers
monitoring the patient's clinical response and plasma drug levels
decrease likelihood of an
using the simplest regimen possible
elderly patient experiencing an
monitoring for drug-drug interactions and iatrogenic illness
adverse drug reaction?
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the
Beers list
simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
How can we promote
clearly labeling and dispensing easy-to-open containers
medication adherence with
developing daily reminders
elderly patients?
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be Need nitrate free interval so tolerance doesn't develop
taken no later than 4 PM?
