PHMY 790 lab final questions and
answers graded A+ updated
A practice in which a licensed pharmacist combines mixes or alters ingredients of a drug to
create a medication tailored to the needs of an individual patient - correct answer ✔✔what is
compounding?
any manipulation of a sterile or non-sterile product intended to produce a sterile final product -
correct answer ✔✔what is sterile compounding?
free from living organisms, especially pathogenic microorganisms - correct answer ✔✔what
does sterile mean?
a sterile drug product that was prepared by compounding or underwent other handling or
manipulation prior to administration - correct answer ✔✔what is a compounded sterile product
(CSP)?
administration that occurs outside of the intestinal tract - correct answer ✔✔what is parenteral
administration?
- intravenous
- intramuscular
- subcutaneous
- intradermal
- epidural
- intra-arterial
- intra-articular
,- intraocular
- intraperitoneal
- intracardiac
- eye (sometimes ear) preparations
- inhalation products
- cardioplegic solutions - correct answer ✔✔what are some examples of parenteral routes?
1. delivery of medications/nutrition to patients who are unable to receive them PO
2. bypass GI thus circumvents the effects of GI tract on medications/first pass metabolism
3. faster onset of action
4. longer duration of action
5. localized or systemic effect - correct answer ✔✔what are 5 advantages to parenteral
therapy?
1. infection
2. air embolus
3. cost
4. only highly trained personnel can prepare or administer
5. pain and discomfort to patient
6. physiological effects difficult to reverse - correct answer ✔✔what are 6 disadvantages of
parenteral therapy?
an independent organization that publishes standards for identity, quality, strength, purity,
packaging and labeling - correct answer ✔✔what is the United States Pharmacopeia (USP)?
chapters <1> to <999> - correct answer ✔✔what chapters of the USP standards are considered
ENFORCEABLE?
, <1000> to <1999> - correct answer ✔✔what chapters of the USP standards are considered
guidelines?
sterile compounding - correct answer ✔✔what is USP standard <797>?
- the environmental influences quality of compounded sterile preparations (CSPs)
- environmental controls crucial in protection of sterile preparations from contamination
- environmental controls also designed to protect operator from hazardous agents (chemo) -
correct answer ✔✔what is the importance of environmental control in sterile compounding?
International Organization of Standards - correct answer ✔✔what is ISO?
ISO Class 1 - correct answer ✔✔Which ISO class is the "cleanest" per cleanroom specifications?
ISO Class 9 - correct answer ✔✔Which ISO class is the "dirtiest" per cleanroom specifications?
ISO Class 5 - correct answer ✔✔hospital cleanroom sterile compounding area is which ISO
Class?
- device or room that provides an ISO Class 5 environment for CSPs
- rely on special type of high efficiency particulate air filter (HEPA) that is >99.97% efficient in
removing particles as small as 0.3 micron
- work adjunct to secondary engineering controls to control air quality - correct answer
✔✔what are some primary engineering controls?
- areas surrounding PECs
- must be controlled and maintained properly to prevent contamination
answers graded A+ updated
A practice in which a licensed pharmacist combines mixes or alters ingredients of a drug to
create a medication tailored to the needs of an individual patient - correct answer ✔✔what is
compounding?
any manipulation of a sterile or non-sterile product intended to produce a sterile final product -
correct answer ✔✔what is sterile compounding?
free from living organisms, especially pathogenic microorganisms - correct answer ✔✔what
does sterile mean?
a sterile drug product that was prepared by compounding or underwent other handling or
manipulation prior to administration - correct answer ✔✔what is a compounded sterile product
(CSP)?
administration that occurs outside of the intestinal tract - correct answer ✔✔what is parenteral
administration?
- intravenous
- intramuscular
- subcutaneous
- intradermal
- epidural
- intra-arterial
- intra-articular
,- intraocular
- intraperitoneal
- intracardiac
- eye (sometimes ear) preparations
- inhalation products
- cardioplegic solutions - correct answer ✔✔what are some examples of parenteral routes?
1. delivery of medications/nutrition to patients who are unable to receive them PO
2. bypass GI thus circumvents the effects of GI tract on medications/first pass metabolism
3. faster onset of action
4. longer duration of action
5. localized or systemic effect - correct answer ✔✔what are 5 advantages to parenteral
therapy?
1. infection
2. air embolus
3. cost
4. only highly trained personnel can prepare or administer
5. pain and discomfort to patient
6. physiological effects difficult to reverse - correct answer ✔✔what are 6 disadvantages of
parenteral therapy?
an independent organization that publishes standards for identity, quality, strength, purity,
packaging and labeling - correct answer ✔✔what is the United States Pharmacopeia (USP)?
chapters <1> to <999> - correct answer ✔✔what chapters of the USP standards are considered
ENFORCEABLE?
, <1000> to <1999> - correct answer ✔✔what chapters of the USP standards are considered
guidelines?
sterile compounding - correct answer ✔✔what is USP standard <797>?
- the environmental influences quality of compounded sterile preparations (CSPs)
- environmental controls crucial in protection of sterile preparations from contamination
- environmental controls also designed to protect operator from hazardous agents (chemo) -
correct answer ✔✔what is the importance of environmental control in sterile compounding?
International Organization of Standards - correct answer ✔✔what is ISO?
ISO Class 1 - correct answer ✔✔Which ISO class is the "cleanest" per cleanroom specifications?
ISO Class 9 - correct answer ✔✔Which ISO class is the "dirtiest" per cleanroom specifications?
ISO Class 5 - correct answer ✔✔hospital cleanroom sterile compounding area is which ISO
Class?
- device or room that provides an ISO Class 5 environment for CSPs
- rely on special type of high efficiency particulate air filter (HEPA) that is >99.97% efficient in
removing particles as small as 0.3 micron
- work adjunct to secondary engineering controls to control air quality - correct answer
✔✔what are some primary engineering controls?
- areas surrounding PECs
- must be controlled and maintained properly to prevent contamination
