Basic and Clinical Pharmacology 15th Edition
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Katzung Trevor Test Bank Update 2023/2024
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TESTBANK f
, Page 2 of 822 f f f
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a patient who is having a
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computed tomography (CT) scan. The nurse working on the oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
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a 14-month-old child as a routine immunization. Which branch of
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pharmacology best describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are f f f f f f f f f f f
involved with clinical pharmacology or pharmacotherapeutics, which is a
f f f f f f f f f
branch of pharmacology that deals with the uses of drugs to treat, prevent, and
f f f f f f f f f f f f f f
diagnose disease. The radiology nurse is administering a drug to help
f f f f f f f f f f f
diagnose a disease. The oncology nurse is administering a drug to help treat a
f f f f f f f f f f f f f f
disease. Pharmacoeconomics includes any costs involved in drug therapy.
f f f f f f f f f
Pharmacodynamics involves how a drug affects the body and pharmacokinetics f f f f f f f f f
is how the body acts on the body.
f f f f f f f f
2. When involved in phase III drug evaluation studies, what responsibilities
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would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects f f f f f f f
D) Conducting research to determine effectiveness of the drug f f f f f f f
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, Page 3 of 822 f f f
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
f f f f f f f f f f f f f f
patients are asked to record any symptoms they experience while taking the
f f f f f f f f f f f f
drugs. Nurses may be responsible for helping collect and analyze the
f f f f f f f f f f f
information to be shared with the Food and Drug Administration (FDA) but
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would not conduct research independently because nurses do not prescribe
f f f f f f f f f f
medications. Use of animals in drug testing is done in the preclinical trials.
f f f f f f f f f f f f f
Select patients who are involved in phase II studies to participate in studies
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where the participants have the disease the drug is intended to treat. These
f f f f f f f f f f f f f
patients are monitored closely for drug action and adverse effects. Phase I
f f f f f f f f f f f f
studies involve healthy human volunteers who are usually paid for their
f f f f f f f f f f f
participation. Nurses may observe for adverse effects and toxicity.
f f f f f f f f f
3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
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The nurse is aware this drug has a high abuse potential. Under what category
f f f f f f f f f f f f f f
would morphine be classified?
f f f f
A) Schedule I f
B) Schedule II f
C) Schedule III f
D) Schedule IV f
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs
f f f f f f f f f f f
because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser abuse
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potential than II and an accepted medical use. Schedule IV drugs have low
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abuse potential and limited dependence liability.
f f f f f f
WWW.THENURSINGMASTERY.COM
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, Page 4 of 822 f f f
4. What concept is considered when generic drugs are substituted for brand
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name drugs?
f f
A) Bioavailability
B) Critical concentration f
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic f f f f f f f f f f f f f
circulation and is available to act on body cells. Binders used in a generic
f f f f f f f f f f f f f f
drug may not be the same as those used in the brand name drug. Therefore,
f f f f f f f f f f f f f f f
the way the body breaks down and uses the drug may differ, which may
f f f f f f f f f f f f f f
eliminate a generic drug substitution. Critical concentration is the amount of a
f f f f f f f f f f f f
drug that is needed to cause a therapeutic effect and should not differ
f f f f f f f f f f f f f
between generic and brand name medications. Distribution is the phase of
f f f f f f f f f f f
pharmacokinetics, which involves the movement of a drug to the bodys
f f f f f f f f f f f
tissues and is the same in generic and brand name drugs. A drugs half-life is
f f f f f f f f f f f f f f f
the time it takes for the amount of drug to decrease to half the peak level,
f f f f f f f f f f f f f f f f
which should not change when substituting a generic medication.
f f f f f f f f f
5. A nurse is assessing the patients home medication use. After listening to the
f f f f f f f f f f f f
patient list current medications, the nurse asks what priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
WWW.THENURSINGMASTERY.COM
www.stuvia.com
f f f f f f
Katzung Trevor Test Bank Update 2023/2024
f f f f f f
TESTBANK f
, Page 2 of 822 f f f
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
f f f f f f f f f
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
f f f f f f f f f f f
1. A nurse working in radiology administers iodine to a patient who is having a
f f f f f f f f f f f f f
computed tomography (CT) scan. The nurse working on the oncology unit
f f f f f f f f f f f
administers chemotherapy to patients who have cancer. At the Public Health
f f f f f f f f f f f
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
f f f f f f f f f
a 14-month-old child as a routine immunization. Which branch of
f f f f f f f f f f
pharmacology best describes the actions of all three nurses?
f f f f f f f f f
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are f f f f f f f f f f f
involved with clinical pharmacology or pharmacotherapeutics, which is a
f f f f f f f f f
branch of pharmacology that deals with the uses of drugs to treat, prevent, and
f f f f f f f f f f f f f f
diagnose disease. The radiology nurse is administering a drug to help
f f f f f f f f f f f
diagnose a disease. The oncology nurse is administering a drug to help treat a
f f f f f f f f f f f f f f
disease. Pharmacoeconomics includes any costs involved in drug therapy.
f f f f f f f f f
Pharmacodynamics involves how a drug affects the body and pharmacokinetics f f f f f f f f f
is how the body acts on the body.
f f f f f f f f
2. When involved in phase III drug evaluation studies, what responsibilities
f f f f f f f f f
would the nurse have?
f f f f
A) Working with animals who are given experimental drugs
f f f f f f f
B) Choosing appropriate patients to be involved in the drug study
f f f f f f f f f
C) Monitoring and observing patients closely for adverse effects f f f f f f f
D) Conducting research to determine effectiveness of the drug f f f f f f f
WWW.THENURSINGMASTERY.COM
www.stuvia.com
, Page 3 of 822 f f f
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
f f f f f f f f f f f f f f
patients are asked to record any symptoms they experience while taking the
f f f f f f f f f f f f
drugs. Nurses may be responsible for helping collect and analyze the
f f f f f f f f f f f
information to be shared with the Food and Drug Administration (FDA) but
f f f f f f f f f f f f
would not conduct research independently because nurses do not prescribe
f f f f f f f f f f
medications. Use of animals in drug testing is done in the preclinical trials.
f f f f f f f f f f f f f
Select patients who are involved in phase II studies to participate in studies
f f f f f f f f f f f f f
where the participants have the disease the drug is intended to treat. These
f f f f f f f f f f f f f
patients are monitored closely for drug action and adverse effects. Phase I
f f f f f f f f f f f f
studies involve healthy human volunteers who are usually paid for their
f f f f f f f f f f f
participation. Nurses may observe for adverse effects and toxicity.
f f f f f f f f f
3. A physician has ordered intramuscular (IM) injections of morphine, a
f f f f f f f f f
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
f f f f f f f f f f f f f f
The nurse is aware this drug has a high abuse potential. Under what category
f f f f f f f f f f f f f f
would morphine be classified?
f f f f
A) Schedule I f
B) Schedule II f
C) Schedule III f
D) Schedule IV f
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs
f f f f f f f f f f f
because of severe dependence liability. Schedule I drugs have high abuse
f f f f f f f f f f f
potential and no accepted medical use. Schedule III drugs have a lesser abuse
f f f f f f f f f f f f f
potential than II and an accepted medical use. Schedule IV drugs have low
f f f f f f f f f f f f f
abuse potential and limited dependence liability.
f f f f f f
WWW.THENURSINGMASTERY.COM
www.stuvia.com
, Page 4 of 822 f f f
4. What concept is considered when generic drugs are substituted for brand
f f f f f f f f f f
name drugs?
f f
A) Bioavailability
B) Critical concentration f
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic f f f f f f f f f f f f f
circulation and is available to act on body cells. Binders used in a generic
f f f f f f f f f f f f f f
drug may not be the same as those used in the brand name drug. Therefore,
f f f f f f f f f f f f f f f
the way the body breaks down and uses the drug may differ, which may
f f f f f f f f f f f f f f
eliminate a generic drug substitution. Critical concentration is the amount of a
f f f f f f f f f f f f
drug that is needed to cause a therapeutic effect and should not differ
f f f f f f f f f f f f f
between generic and brand name medications. Distribution is the phase of
f f f f f f f f f f f
pharmacokinetics, which involves the movement of a drug to the bodys
f f f f f f f f f f f
tissues and is the same in generic and brand name drugs. A drugs half-life is
f f f f f f f f f f f f f f f
the time it takes for the amount of drug to decrease to half the peak level,
f f f f f f f f f f f f f f f f
which should not change when substituting a generic medication.
f f f f f f f f f
5. A nurse is assessing the patients home medication use. After listening to the
f f f f f f f f f f f f
patient list current medications, the nurse asks what priority question?
f f f f f f f f f f
A) Do you take any generic medications?
f f f f f
B) Are any of these medications orphan drugs?
f f f f f f
C) Are these medications safe to take during pregnancy?
f f f f f f f
D) Do you take any over-the-counter medications?
f f f f f
Ans: D
Feedback:
WWW.THENURSINGMASTERY.COM
www.stuvia.com
