UWORLD/COMBANK Exam Questions with Correct Answers Verified by Experts|
Latest Update
What is the alternative treatment to prevent cardiovascular events for a patient who cannot
take aspirin? Clopidogrel
Blocks P2Y2 component of ADP receptors on platelet surface therefore preventing aggregation.
What two drugs are used for the prevention or treatment of thromboembolic events?
Apixaban and Warfarin
Apixaban is a direct factor Xa inhibitor
Warfarin inhibits enzyme needed to make vitamin K therefore decreasing synthesis of clotting
factors 1972
What is the insulin mediated receptor? Where are these receptors located in the body?
GLUT 4
muscle cells and adipocytes
What is the insulin independent receptor? Where is the insulin independent receptor located in
the body? GLUT 1, 2, 3, and 5
Brain
Kidney
Intestine
Liver
Red blood cells
,What are the EKG findings on atrial fibrillation?
What determines the ventricular contraction rate? absent P waves
irregularly irregular RR intervals
narrow QRS complex
AV node refractory period
What disease is associated with the triad of hemolytic anemia, hypercoagulability, and
pancytopenia? What is the mutation? What is the deficiency? paroxysmal nocturnal
hemoglobinuria (PNH)
Caused by a mutation in the PIGA gene
Associated with deficiency of CD 55 and CD 59
What types of viruses are inactivated by ether? enveloped viruses
What tumor that occurs in the kidney is composed of blood vessels, smooth muscle, and fat?
Renal angiomyolipoma
What condition is associated with bilateral renal angiomyolipomas? tuberous sclerosis
autosomal dominant
associated with hamartomas of brain and ash leaf patches
What studies need to be obtained with a patient taking olanzapine or clozapine? BMI
fasting glucose
lipid levels
, blood pressure
waist circumference
In carbon monoxide poisoning, what are the concentrations of carboxyhemoglobin and
methemoglobinemia? What is the partial pressure of oxygen? increased carboxyhemoglobin
normal methemoglobinemia
normal partial pressure of oxygen
For a drug metabolized by first order kinetics, how many half lives to steady state? 4 to 5
At what site of the cell is rRNA made? nucelolus
What is the cause of Goodpasture syndrome? Autoantibodies against the alpha 3 chain of
type IV collagen found in glomerular basement membrane and pulmonary capillary membrane
Also known as anti GBM antibodies
What is the leukemia associated with children? Acute lymphoblastic leukemia
How do you differentiate the type of leukemia with blasts are present on blood smear? Both
B lymphoblasts and T lymphoblasts contain TdT
B lymphoblasts have CD 10, CD 19, and CD20
T lymphoblasts have CD 2, CD 3, CD 4, CD, 5, CD 7, and CD 8
Latest Update
What is the alternative treatment to prevent cardiovascular events for a patient who cannot
take aspirin? Clopidogrel
Blocks P2Y2 component of ADP receptors on platelet surface therefore preventing aggregation.
What two drugs are used for the prevention or treatment of thromboembolic events?
Apixaban and Warfarin
Apixaban is a direct factor Xa inhibitor
Warfarin inhibits enzyme needed to make vitamin K therefore decreasing synthesis of clotting
factors 1972
What is the insulin mediated receptor? Where are these receptors located in the body?
GLUT 4
muscle cells and adipocytes
What is the insulin independent receptor? Where is the insulin independent receptor located in
the body? GLUT 1, 2, 3, and 5
Brain
Kidney
Intestine
Liver
Red blood cells
,What are the EKG findings on atrial fibrillation?
What determines the ventricular contraction rate? absent P waves
irregularly irregular RR intervals
narrow QRS complex
AV node refractory period
What disease is associated with the triad of hemolytic anemia, hypercoagulability, and
pancytopenia? What is the mutation? What is the deficiency? paroxysmal nocturnal
hemoglobinuria (PNH)
Caused by a mutation in the PIGA gene
Associated with deficiency of CD 55 and CD 59
What types of viruses are inactivated by ether? enveloped viruses
What tumor that occurs in the kidney is composed of blood vessels, smooth muscle, and fat?
Renal angiomyolipoma
What condition is associated with bilateral renal angiomyolipomas? tuberous sclerosis
autosomal dominant
associated with hamartomas of brain and ash leaf patches
What studies need to be obtained with a patient taking olanzapine or clozapine? BMI
fasting glucose
lipid levels
, blood pressure
waist circumference
In carbon monoxide poisoning, what are the concentrations of carboxyhemoglobin and
methemoglobinemia? What is the partial pressure of oxygen? increased carboxyhemoglobin
normal methemoglobinemia
normal partial pressure of oxygen
For a drug metabolized by first order kinetics, how many half lives to steady state? 4 to 5
At what site of the cell is rRNA made? nucelolus
What is the cause of Goodpasture syndrome? Autoantibodies against the alpha 3 chain of
type IV collagen found in glomerular basement membrane and pulmonary capillary membrane
Also known as anti GBM antibodies
What is the leukemia associated with children? Acute lymphoblastic leukemia
How do you differentiate the type of leukemia with blasts are present on blood smear? Both
B lymphoblasts and T lymphoblasts contain TdT
B lymphoblasts have CD 10, CD 19, and CD20
T lymphoblasts have CD 2, CD 3, CD 4, CD, 5, CD 7, and CD 8
