, Pharm Test 1 (Chap 1-11)
Questions With Verified Answers
,The nurse is obtaining consent from a subject newly recruited for a clinical drug trial that will last for 6
b b b b b b b b b b b b b b b b b b b
months. All subjects will be given gift certificates for participating. One subject says, "Well, I guess if the
b b b b b b b b b b b b b b b b b b
drug doesn't work, I'll just have to put up with the symptoms for 6 months." What will the nurse tell the
b b b b b b b b b b b b b b b b b b b b b
subject?
b b
a. "Participation for the duration of the study is required."
b b b b b b b b b b
b. "Participation may end at any time without penalty."
b b b b b b b b b
c. "Withdrawal from the study may end at any time, but the gift certificate will not be given."
b b b b b b b b b b b b b b b b b b
d. "You can request placement in the treatment group." << ANS>>"Participation may end at any time
b b b b b b b b b b b b b b b
without penalty."
b b
The nurse is assisting with a clinical drug trial in which the side effects of two effective drugs are being
b b b b b b b b b b b b b b b b b b b
compared. A patient who would benefit from either drug has elected to withdraw from the study, and
b b b b b b b b b b b b b b b b b
the nurse assists with the paperwork to facilitate this. This is an example of
b b b b b b b b b b b b b b b
a. autonomy.
b b
b. beneficence.
b b
c. justice.
b b
d. veracity << ANS>>autonomy
b b b
During a clinical drug trial for a new medication, researchers note a previously unknown serious adverse
b b b b b b b b b b b b b b b
effect occurring in more than 50% of subjects. The study is discontinued. Which ethical principle is being
b b b b b b b b b b b b b b b b b
exercised?
b b
a. Beneficence
b b
b. Justice
b b
c. Respect for persons
b b b b
d. Veracity << ANS>>Beneficence
b b b
In a 5-year experimental clinical trial to investigate a new cancer treatment, researchers in the second
b b b b b b b b b b b b b b b
byear note overwhelming improvement in almost all of the subjects in the treatment group. The lead
b b b b b b b b b b b b b b b
bresearcher elects to continue the study. Which ethical principle is being violated?
b b b b b b b b b b b b
a. Beneficence
b b
b. Justice
b b
, c. Respect for persons
b b b b
d. Veracity << ANS>>Justice
b b b
The nurse is enrolling subjects for a double-blind experimental study. One patient asks the nurse to
b b b b b b b b b b b b b b b
explain the role of the experimental group. The nurse will explain that subjects in the experimental
b b b b b b b b b b b b b b b b
group in this type of study
b b b b b b b
a. are selected for participation in that group.
b b b b b b b b
b. have unique baseline characteristics.
b b b b b
c. receive a placebo.
b b b b
d. receive the treatment being evaluated. << ANS>>receive the treatment being evaluated
b b b b b b b b b b b
The nurse is obtaining signatures on consent forms for participation in a clinical drug trial. One patient
b b b b b b b b b b b b b b b b
says, "I'm not sure I want to do this, but I need the cash." The nurse will take which action?
b b b b b b b b b b b b b b b b b b b b b
a. Ask the patient to clarify concerns.
b b b b b b b
b. Reinforce that cash is given to all subjects equally.
b b b b b b b b b b
c. Report this statement to the party named on the consent.
b b b b b b b b b b b
d. Review the elements of the study and obtain consent. << ANS>>Report this statement to the party
b b b b b b b b b b b b b b b b
named on the consent
b b b b
Which is the characteristic of preclinical in vivo testing?
b b b b b b b b b
a. A comparison of experimental and control data in animals
b b b b b b b b b b
b. A study conducted in a test tube in a laboratory
b b b b b b b b b b b
c. A study that determines the effects of the placebo in human participants
b b b b b b b b b b b b b
d. A study to assess the seriousness of the disease to be treated << ANS>>A comparison of experimental
b b b b b b b b b b b b b b b b b
and control data in animals
b b b b b
Many drugs marketed in the 1980s may not be effective in a majority of the population. The nurse
b b b b b b b b b b b b b b b b b
understands that this is because these drugs
b b b b b b b b
a. did not pass through the appropriate phases of clinical trials.
b b b b b b b b b b b
b. did not require human subject protections and are invalid.
b b b b b b b b b b
c. were not tested on women, minorities, or children.
b b b b b b b b b
d. were tested on healthy subjects only. << ANS>>were not tested on women, minorities, or children.
b b b b b b b b b b b b b b b
The nurse is assisting with data collection in a study of drug effects in healthy subjects. The nurse assists
b b b b b b b b b b b b b b b b b b
with blood and urine collection to determine serum drug levels and the presence of metabolites in the
b b b b b b b b b b b b b b b b b
urine. Which phase of a drug study does this represent?
b b b b b b b b b b b
a. Phase I
b b b
Questions With Verified Answers
,The nurse is obtaining consent from a subject newly recruited for a clinical drug trial that will last for 6
b b b b b b b b b b b b b b b b b b b
months. All subjects will be given gift certificates for participating. One subject says, "Well, I guess if the
b b b b b b b b b b b b b b b b b b
drug doesn't work, I'll just have to put up with the symptoms for 6 months." What will the nurse tell the
b b b b b b b b b b b b b b b b b b b b b
subject?
b b
a. "Participation for the duration of the study is required."
b b b b b b b b b b
b. "Participation may end at any time without penalty."
b b b b b b b b b
c. "Withdrawal from the study may end at any time, but the gift certificate will not be given."
b b b b b b b b b b b b b b b b b b
d. "You can request placement in the treatment group." << ANS>>"Participation may end at any time
b b b b b b b b b b b b b b b
without penalty."
b b
The nurse is assisting with a clinical drug trial in which the side effects of two effective drugs are being
b b b b b b b b b b b b b b b b b b b
compared. A patient who would benefit from either drug has elected to withdraw from the study, and
b b b b b b b b b b b b b b b b b
the nurse assists with the paperwork to facilitate this. This is an example of
b b b b b b b b b b b b b b b
a. autonomy.
b b
b. beneficence.
b b
c. justice.
b b
d. veracity << ANS>>autonomy
b b b
During a clinical drug trial for a new medication, researchers note a previously unknown serious adverse
b b b b b b b b b b b b b b b
effect occurring in more than 50% of subjects. The study is discontinued. Which ethical principle is being
b b b b b b b b b b b b b b b b b
exercised?
b b
a. Beneficence
b b
b. Justice
b b
c. Respect for persons
b b b b
d. Veracity << ANS>>Beneficence
b b b
In a 5-year experimental clinical trial to investigate a new cancer treatment, researchers in the second
b b b b b b b b b b b b b b b
byear note overwhelming improvement in almost all of the subjects in the treatment group. The lead
b b b b b b b b b b b b b b b
bresearcher elects to continue the study. Which ethical principle is being violated?
b b b b b b b b b b b b
a. Beneficence
b b
b. Justice
b b
, c. Respect for persons
b b b b
d. Veracity << ANS>>Justice
b b b
The nurse is enrolling subjects for a double-blind experimental study. One patient asks the nurse to
b b b b b b b b b b b b b b b
explain the role of the experimental group. The nurse will explain that subjects in the experimental
b b b b b b b b b b b b b b b b
group in this type of study
b b b b b b b
a. are selected for participation in that group.
b b b b b b b b
b. have unique baseline characteristics.
b b b b b
c. receive a placebo.
b b b b
d. receive the treatment being evaluated. << ANS>>receive the treatment being evaluated
b b b b b b b b b b b
The nurse is obtaining signatures on consent forms for participation in a clinical drug trial. One patient
b b b b b b b b b b b b b b b b
says, "I'm not sure I want to do this, but I need the cash." The nurse will take which action?
b b b b b b b b b b b b b b b b b b b b b
a. Ask the patient to clarify concerns.
b b b b b b b
b. Reinforce that cash is given to all subjects equally.
b b b b b b b b b b
c. Report this statement to the party named on the consent.
b b b b b b b b b b b
d. Review the elements of the study and obtain consent. << ANS>>Report this statement to the party
b b b b b b b b b b b b b b b b
named on the consent
b b b b
Which is the characteristic of preclinical in vivo testing?
b b b b b b b b b
a. A comparison of experimental and control data in animals
b b b b b b b b b b
b. A study conducted in a test tube in a laboratory
b b b b b b b b b b b
c. A study that determines the effects of the placebo in human participants
b b b b b b b b b b b b b
d. A study to assess the seriousness of the disease to be treated << ANS>>A comparison of experimental
b b b b b b b b b b b b b b b b b
and control data in animals
b b b b b
Many drugs marketed in the 1980s may not be effective in a majority of the population. The nurse
b b b b b b b b b b b b b b b b b
understands that this is because these drugs
b b b b b b b b
a. did not pass through the appropriate phases of clinical trials.
b b b b b b b b b b b
b. did not require human subject protections and are invalid.
b b b b b b b b b b
c. were not tested on women, minorities, or children.
b b b b b b b b b
d. were tested on healthy subjects only. << ANS>>were not tested on women, minorities, or children.
b b b b b b b b b b b b b b b
The nurse is assisting with data collection in a study of drug effects in healthy subjects. The nurse assists
b b b b b b b b b b b b b b b b b b
with blood and urine collection to determine serum drug levels and the presence of metabolites in the
b b b b b b b b b b b b b b b b b
urine. Which phase of a drug study does this represent?
b b b b b b b b b b b
a. Phase I
b b b
