FULL TEST BANK
KATZUNG'S BASIC AND CLINICAL PHARMACOLOGY, 16TH
EDITION
By Todd W. Vanderah All Chaptes 1-65 With Answers
,TABLE OF CONTENTS
Chapter 1. Introduction: The Nature Of Drugs & Drug Development & Regulation ............................................ 4
Chapter 2. Drug Receptors & Pharmacodynamics ................................................................................................ 25
Chapter 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & The Time Course OfDrug Action.... 25
Chapter 4. Drug Biotransformation ....................................................................................................................... 25
Chapter 5. Pharmacogenomics ............................................................................................................................... 25
Chapter 6. Introduction To Autonomic Pharmacology ......................................................................................... 49
Chapter 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs ........................................................... 72
Chapter 8. Cholinoceptor-Blocking Drugs ............................................................................................................. 91
Chapter 9. Adrenoceptor Agonists & Sympathomimetic Drugs\1. ...................................................................... 110
Chapter 10. Adrenoceptor Antagonist Drugs ....................................................................................................... 129
Chapter 11. Antihypertensive Agents .................................................................................................................... 148
Chapter 12. Vasodilators & The Treatment Of Angina Pectoris ......................................................................... 169
Chapter 13. Drugs Used In Heart Failure ............................................................................................................ 186
Chapter 14. Agents Used In Cardiac Arrhythmias............................................................................................... 203
Chapter 15. Diuretic Agents .................................................................................................................................. 223
Chapter 16- Histamine, Serotonin, & The Ergot Alkaloids ................................................................................... 243
Chapter 17. VasoactivePeptides............................................................................................................................. 243
Chapter 18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & RelatedCompounds ................. 254
Chapter 19. Nitric Oxide Drugs Used In Asthma .................................................................................................. 261
Chapter 21. Introduction To The Pharmacology Of CNS Drugs ........................................................................... 261
Chapter 22.Sedative-Hypnotic Drugs ................................................................................................................... 282
Chapter 23. The Alcohols ...................................................................................................................................... 282
Chapter 24. Antiseizure Drugs ............................................................................................................................... 307
Chapter 25 .General Anesthetics............................................................................................................................ 328
Chapter 26. Local Anesthetics................................................................................................................................ 328
Chapter 27. Skeletal Muscle Relaxants ................................................................................................................ 348
Chapter 28. Pharmacologic Management Of Parkinsonism & Other Movement Disorders.............................. 366
Chapter 29. Antipsychotic Agents & Lithium ........................................................................................................ 386
Chapter 30. Antidepressant Agents ........................................................................................................................ 405
Chapter 31. Opioid Agonists & Antagonists .......................................................................................................... 427
Chapter 32. Drugs Of Abuse .................................................................................................................................. 427
Chapter 33. Agents Used In Cytopenias; Hematopoietic Growth Factors ............................................................. 446
Chapter 34. Drugs Used In Disorders Of Coagulation ........................................................................................... 463
Chapter 35. Agents Used In Dyslipidemia ............................................................................................................. 480
Chapter 36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs,Nonopioid
Analgesics, & Drugs Used In Gout ........................................................................................................................ 500
Chapter 37. Hypothalamic & Pituitary Hormones ................................................................................................. 500
,Chapter 38. Thyroid & Antithyroid Drugs ............................................................................................................. 518
Chapter 39. Adrenocorticosteroids & Adrenocortical Antagonists ........................................................................ 536
Chapter 40. The Gonadal Hormones & Inhibitors.................................................................................................. 555
Chapter 42. Agents That Affect Bone Mineral Homeostasis ................................................................................. 555
Chapter 43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics ................................................... 576
Chapter 44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones ..... 576
Chapter 45. Aminoglycosides & Spectinomycin ................................................................................................... 576
Chapter 46. Sulfonamides,Trimethoprim, & Quinolones ...................................................................................... 576
Chapter 47. Antimycobacterial Drugs .................................................................................................................... 576
Chapter 48. Antifungal Agents ............................................................................................................................... 601
Chapter 49. Antiviral Agents.................................................................................................................................. 621
Chapter 50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants ................................. 642
Chapter 51. Clinical Use Of Antimicrobial Agents................................................................................................ 642
Chapter 52. Antiprotozoal Drugs ........................................................................................................................... 667
Chapter 53. Clinical Pharmacology Of The Antihelminthic Drugs........................................................................ 685
Chapter 54. Cancer Chemotherapy ........................................................................................................................ 704
Chapter 55. Immunopharmacology ........................................................................................................................ 726
Chapter 56.Introduction To Toxicology: Occupational & Environmental ........................................................... 747
Chapter 57. Heavy Metal Intoxication & Chelators ............................................................................................... 747
Chapter 58. Management Of The PoisonedPatient ................................................................................................ 747
Chapter 59. Special Aspects Of Perinatal & Pediatric Pharmacology ................................................................... 793
Chapter 60. Special Aspects Of Geriatric Pharmacology ...................................................................................... 804
Chapter 61. Dermatologic Pharmacology .............................................................................................................. 811
Chapter 62. Drugs Used In The Treatment Of Gastrointestinal Diseases .............................................................. 816
Chapter 63. Therapeutic & Toxic Potential Of Over-The-Counter Agents ............................................................ 835
Chapter 64. Dietary Supplements & Herbal Medications ...................................................................................... 856
Chapter 65. Rational Prescribing & Prescription Writing ...................................................................................... 860
Chapter 66. Important Drug Interactions & Their Mechanisms ............................................................................ 860
, Chapter 1. Introduction: The Nature Of Drugs & Drug Development &
Regulation
1. A Nurse Working In Radiology Administers Iodine To A Patient Who Is
Having A Computed Tomography (CT) Scan. The Nurse Working On The
Oncology Unit Administers Chemotherapy To Patients Who Have Cancer.
At The Public Health Department, A Nurse Administers A Measles-Mumps-
Rubella (MMR) Vaccine ToA 14-Month-Old Child As A Routine
Immunization. Which Branch Of Pharmacology Best Describes The Actions
Of All Three Nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANS: B
FEEDBACK
Pharmacology Is The Study Of The Biologic Effects Of Chemicals. Nurses
Are Involved With Clinical Pharmacology Or Pharmacotherapeutics, Which
Is A Branch Of Pharmacology That Deals With The Uses Of Drugs To Treat,
Prevent, And Diagnose Disease. The Radiology Nurse Is Administering A
Drug To Help Diagnose A Disease. The Oncology Nurse Is Administering A
Drug To Help Treat ADisease. Pharmacoeconomics Includes Any Costs
Involved In Drug Therapy.
Pharmacodynamics Involves How A Drug Affects The Body
AndPharmacokinetics Is How The Body Acts On The Body.
2. A Physician Has Ordered Intramuscular (IM) Injections Of Morphine, A
Narcotic, Every 4 Hours As Needed For Pain In A Motor Vehicle Accident
Victim.The Nurse Is Aware This Drug Has A High Abuse Potential. Under
What CategoryWould Morphine Be Classified?
A) Schedule I
B) Schedule II
KATZUNG'S BASIC AND CLINICAL PHARMACOLOGY, 16TH
EDITION
By Todd W. Vanderah All Chaptes 1-65 With Answers
,TABLE OF CONTENTS
Chapter 1. Introduction: The Nature Of Drugs & Drug Development & Regulation ............................................ 4
Chapter 2. Drug Receptors & Pharmacodynamics ................................................................................................ 25
Chapter 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & The Time Course OfDrug Action.... 25
Chapter 4. Drug Biotransformation ....................................................................................................................... 25
Chapter 5. Pharmacogenomics ............................................................................................................................... 25
Chapter 6. Introduction To Autonomic Pharmacology ......................................................................................... 49
Chapter 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs ........................................................... 72
Chapter 8. Cholinoceptor-Blocking Drugs ............................................................................................................. 91
Chapter 9. Adrenoceptor Agonists & Sympathomimetic Drugs\1. ...................................................................... 110
Chapter 10. Adrenoceptor Antagonist Drugs ....................................................................................................... 129
Chapter 11. Antihypertensive Agents .................................................................................................................... 148
Chapter 12. Vasodilators & The Treatment Of Angina Pectoris ......................................................................... 169
Chapter 13. Drugs Used In Heart Failure ............................................................................................................ 186
Chapter 14. Agents Used In Cardiac Arrhythmias............................................................................................... 203
Chapter 15. Diuretic Agents .................................................................................................................................. 223
Chapter 16- Histamine, Serotonin, & The Ergot Alkaloids ................................................................................... 243
Chapter 17. VasoactivePeptides............................................................................................................................. 243
Chapter 18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & RelatedCompounds ................. 254
Chapter 19. Nitric Oxide Drugs Used In Asthma .................................................................................................. 261
Chapter 21. Introduction To The Pharmacology Of CNS Drugs ........................................................................... 261
Chapter 22.Sedative-Hypnotic Drugs ................................................................................................................... 282
Chapter 23. The Alcohols ...................................................................................................................................... 282
Chapter 24. Antiseizure Drugs ............................................................................................................................... 307
Chapter 25 .General Anesthetics............................................................................................................................ 328
Chapter 26. Local Anesthetics................................................................................................................................ 328
Chapter 27. Skeletal Muscle Relaxants ................................................................................................................ 348
Chapter 28. Pharmacologic Management Of Parkinsonism & Other Movement Disorders.............................. 366
Chapter 29. Antipsychotic Agents & Lithium ........................................................................................................ 386
Chapter 30. Antidepressant Agents ........................................................................................................................ 405
Chapter 31. Opioid Agonists & Antagonists .......................................................................................................... 427
Chapter 32. Drugs Of Abuse .................................................................................................................................. 427
Chapter 33. Agents Used In Cytopenias; Hematopoietic Growth Factors ............................................................. 446
Chapter 34. Drugs Used In Disorders Of Coagulation ........................................................................................... 463
Chapter 35. Agents Used In Dyslipidemia ............................................................................................................. 480
Chapter 36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs,Nonopioid
Analgesics, & Drugs Used In Gout ........................................................................................................................ 500
Chapter 37. Hypothalamic & Pituitary Hormones ................................................................................................. 500
,Chapter 38. Thyroid & Antithyroid Drugs ............................................................................................................. 518
Chapter 39. Adrenocorticosteroids & Adrenocortical Antagonists ........................................................................ 536
Chapter 40. The Gonadal Hormones & Inhibitors.................................................................................................. 555
Chapter 42. Agents That Affect Bone Mineral Homeostasis ................................................................................. 555
Chapter 43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics ................................................... 576
Chapter 44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones ..... 576
Chapter 45. Aminoglycosides & Spectinomycin ................................................................................................... 576
Chapter 46. Sulfonamides,Trimethoprim, & Quinolones ...................................................................................... 576
Chapter 47. Antimycobacterial Drugs .................................................................................................................... 576
Chapter 48. Antifungal Agents ............................................................................................................................... 601
Chapter 49. Antiviral Agents.................................................................................................................................. 621
Chapter 50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants ................................. 642
Chapter 51. Clinical Use Of Antimicrobial Agents................................................................................................ 642
Chapter 52. Antiprotozoal Drugs ........................................................................................................................... 667
Chapter 53. Clinical Pharmacology Of The Antihelminthic Drugs........................................................................ 685
Chapter 54. Cancer Chemotherapy ........................................................................................................................ 704
Chapter 55. Immunopharmacology ........................................................................................................................ 726
Chapter 56.Introduction To Toxicology: Occupational & Environmental ........................................................... 747
Chapter 57. Heavy Metal Intoxication & Chelators ............................................................................................... 747
Chapter 58. Management Of The PoisonedPatient ................................................................................................ 747
Chapter 59. Special Aspects Of Perinatal & Pediatric Pharmacology ................................................................... 793
Chapter 60. Special Aspects Of Geriatric Pharmacology ...................................................................................... 804
Chapter 61. Dermatologic Pharmacology .............................................................................................................. 811
Chapter 62. Drugs Used In The Treatment Of Gastrointestinal Diseases .............................................................. 816
Chapter 63. Therapeutic & Toxic Potential Of Over-The-Counter Agents ............................................................ 835
Chapter 64. Dietary Supplements & Herbal Medications ...................................................................................... 856
Chapter 65. Rational Prescribing & Prescription Writing ...................................................................................... 860
Chapter 66. Important Drug Interactions & Their Mechanisms ............................................................................ 860
, Chapter 1. Introduction: The Nature Of Drugs & Drug Development &
Regulation
1. A Nurse Working In Radiology Administers Iodine To A Patient Who Is
Having A Computed Tomography (CT) Scan. The Nurse Working On The
Oncology Unit Administers Chemotherapy To Patients Who Have Cancer.
At The Public Health Department, A Nurse Administers A Measles-Mumps-
Rubella (MMR) Vaccine ToA 14-Month-Old Child As A Routine
Immunization. Which Branch Of Pharmacology Best Describes The Actions
Of All Three Nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANS: B
FEEDBACK
Pharmacology Is The Study Of The Biologic Effects Of Chemicals. Nurses
Are Involved With Clinical Pharmacology Or Pharmacotherapeutics, Which
Is A Branch Of Pharmacology That Deals With The Uses Of Drugs To Treat,
Prevent, And Diagnose Disease. The Radiology Nurse Is Administering A
Drug To Help Diagnose A Disease. The Oncology Nurse Is Administering A
Drug To Help Treat ADisease. Pharmacoeconomics Includes Any Costs
Involved In Drug Therapy.
Pharmacodynamics Involves How A Drug Affects The Body
AndPharmacokinetics Is How The Body Acts On The Body.
2. A Physician Has Ordered Intramuscular (IM) Injections Of Morphine, A
Narcotic, Every 4 Hours As Needed For Pain In A Motor Vehicle Accident
Victim.The Nurse Is Aware This Drug Has A High Abuse Potential. Under
What CategoryWould Morphine Be Classified?
A) Schedule I
B) Schedule II
