Internal Medicine EOR
Internal Medicine EOR Exam Study Guide
Questions with Verified Answers 2025
A 24-year-old woman presents with complaints of excessive thirst over the past several
weeks. She also notes waking up in the middle of the night to urinate. She recently
underwent transsphenoidal resection of a pituitary adenoma. Which of the following is
the most likely diagnosis?
Central diabetes insipidus
What is the most common presenting symptom of bladder carcinoma?
Painless hematuria
A 25-year-old man presents to the clinic with fever and a sore throat. A throat swab is
performed and the culture comes back positive for group A streptococcus bacteria.
What system of his body is at highest risk for permanent damage if proper treatment for
his infection is not administered?
Cardiovascular
A 60-year-old man with intermittent claudication returns to the clinic for interpretation
of the results of his ankle-brachial index. Which of the following statements is most
accurate?
A falsely high index may indicate severely hardened, non-compressible leg vessels
A 22-year-old man presents to the office for his one week follow-up after his third
concussion in four years. The patient plays rugby on his college intramural team. His
most recent concussion was complicated by a period of loss of consciousness at the time
of injury. He reports having headaches and intermittent dizziness for the past couple of
days. His headache appears to be tension-type in nature. He is eager to return to rugby
and is requesting clearance to play. Which of the following is the most appropriate
education to give your patient?
Cannot return as patient is currently symptomatic
1|Page
,Internal Medicine EOR
A 64-year-old man presents to the clinic reporting a progressive tremor affecting his
hands. He states the symptom onset was approximately seven years ago. He states his
tremor is now affecting his writing but appears to improve in the evenings after a glass
of wine. He has no significant medical history. He does report that his mother had a
similar problem but never sought medical attention. On exam, he has no tremor at rest
but develops an increasing amplitude tremor in both upper extremities when reaching
for items. No bradykinesia or rigidity is present. The rest of his examination is
unremarkable. Which of the following is the most likely diagnosis?
Essential tremor
Which of the following best describes the etiology of the jaundice seen in patients with
thyroid storm?
Hepatic tissue hypoxia due to increased peripheral consumption of oxygen
Which of the following is associated with aortic stenosis?
Syncope
A 32-year-old woman with Marfan syndrome is brought to the emergency department
by her husband after she experienced a syncopal episode. She complains of acute onset
of sharp substernal chest pain with radiation to her back. On arrival, her vital signs are T
37.3C, HR 130, BP 90/40, RR 27. The blood pressure is similar in bilateral arms. Physical
examination reveals no jugular venous distention and heart sounds are auscultated
clearly without murmurs, rubs, or gallops. A CT scan is obtained and shown above.
Which of the following is the most appropriate next step in the management of this
patients condition?
Normal saline
2|Page
, Internal Medicine EOR
A 35-year-old man presents to the office with acute onset right flank pain radiating to
the groin with intermittent nausea and vomiting. A urinalysis and computed tomography
of the abdomen and pelvis without contrast were ordered. An urgent referral for
outpatient urologist evaluation would be most appropriate for which of the following
findings?
A 10.5 mm mid-ureteral stone
A 35-year-old woman presents to the clinic complaining of worsening symptoms related
to her recently diagnosed scleroderma (systemic sclerosis). Which of the following
symptoms is most consistent with the diagnosis of scleroderma?
Skin tightening around the finger with pitting at the fingertips
Which of the following conditions is most commonly associated with malar or "butterfly"
rash?
Systemic lupus erythematosus
A 67-year-old man presents to the clinic for evaluation of cough, wheezing, malaise, and
shortness of breath. His social history is positive for daily cigar smoking for 30 years. He
reports his symptoms have been present for four months. He had a similar presentation
one year ago and was diagnosed with bronchitis. Which of the following is most likely on
physical examination?
Barrel chested
A 35-year-old Caucasian man presents to the emergency department with slurred
speech and right facial drooping. He had a similar episode a few months ago and did not
suffer any residual effects. He also has a history of deep venous thrombosis in the left leg
but has no history of surgeries, hypertension, or diabetes. Which of the following should
be included in the evaluation to determine the cause of this condition?
Lupus anticoagulant
A 44-year-old man presents for a follow-up visit for his known gastroesophageal reflux
disease. He has been taking a histamine-2-receptor antagonist twice a day. He continues
to have symptoms at least three times per week. Which of the following is the next best
therapy?
Omeprazole
A 59-year-old woman presents to the clinic reporting numbness in her hands and around
her mouth, as well as muscle cramps, fatigue, and intermittent hoarseness. Her medical
3|Page
Internal Medicine EOR Exam Study Guide
Questions with Verified Answers 2025
A 24-year-old woman presents with complaints of excessive thirst over the past several
weeks. She also notes waking up in the middle of the night to urinate. She recently
underwent transsphenoidal resection of a pituitary adenoma. Which of the following is
the most likely diagnosis?
Central diabetes insipidus
What is the most common presenting symptom of bladder carcinoma?
Painless hematuria
A 25-year-old man presents to the clinic with fever and a sore throat. A throat swab is
performed and the culture comes back positive for group A streptococcus bacteria.
What system of his body is at highest risk for permanent damage if proper treatment for
his infection is not administered?
Cardiovascular
A 60-year-old man with intermittent claudication returns to the clinic for interpretation
of the results of his ankle-brachial index. Which of the following statements is most
accurate?
A falsely high index may indicate severely hardened, non-compressible leg vessels
A 22-year-old man presents to the office for his one week follow-up after his third
concussion in four years. The patient plays rugby on his college intramural team. His
most recent concussion was complicated by a period of loss of consciousness at the time
of injury. He reports having headaches and intermittent dizziness for the past couple of
days. His headache appears to be tension-type in nature. He is eager to return to rugby
and is requesting clearance to play. Which of the following is the most appropriate
education to give your patient?
Cannot return as patient is currently symptomatic
1|Page
,Internal Medicine EOR
A 64-year-old man presents to the clinic reporting a progressive tremor affecting his
hands. He states the symptom onset was approximately seven years ago. He states his
tremor is now affecting his writing but appears to improve in the evenings after a glass
of wine. He has no significant medical history. He does report that his mother had a
similar problem but never sought medical attention. On exam, he has no tremor at rest
but develops an increasing amplitude tremor in both upper extremities when reaching
for items. No bradykinesia or rigidity is present. The rest of his examination is
unremarkable. Which of the following is the most likely diagnosis?
Essential tremor
Which of the following best describes the etiology of the jaundice seen in patients with
thyroid storm?
Hepatic tissue hypoxia due to increased peripheral consumption of oxygen
Which of the following is associated with aortic stenosis?
Syncope
A 32-year-old woman with Marfan syndrome is brought to the emergency department
by her husband after she experienced a syncopal episode. She complains of acute onset
of sharp substernal chest pain with radiation to her back. On arrival, her vital signs are T
37.3C, HR 130, BP 90/40, RR 27. The blood pressure is similar in bilateral arms. Physical
examination reveals no jugular venous distention and heart sounds are auscultated
clearly without murmurs, rubs, or gallops. A CT scan is obtained and shown above.
Which of the following is the most appropriate next step in the management of this
patients condition?
Normal saline
2|Page
, Internal Medicine EOR
A 35-year-old man presents to the office with acute onset right flank pain radiating to
the groin with intermittent nausea and vomiting. A urinalysis and computed tomography
of the abdomen and pelvis without contrast were ordered. An urgent referral for
outpatient urologist evaluation would be most appropriate for which of the following
findings?
A 10.5 mm mid-ureteral stone
A 35-year-old woman presents to the clinic complaining of worsening symptoms related
to her recently diagnosed scleroderma (systemic sclerosis). Which of the following
symptoms is most consistent with the diagnosis of scleroderma?
Skin tightening around the finger with pitting at the fingertips
Which of the following conditions is most commonly associated with malar or "butterfly"
rash?
Systemic lupus erythematosus
A 67-year-old man presents to the clinic for evaluation of cough, wheezing, malaise, and
shortness of breath. His social history is positive for daily cigar smoking for 30 years. He
reports his symptoms have been present for four months. He had a similar presentation
one year ago and was diagnosed with bronchitis. Which of the following is most likely on
physical examination?
Barrel chested
A 35-year-old Caucasian man presents to the emergency department with slurred
speech and right facial drooping. He had a similar episode a few months ago and did not
suffer any residual effects. He also has a history of deep venous thrombosis in the left leg
but has no history of surgeries, hypertension, or diabetes. Which of the following should
be included in the evaluation to determine the cause of this condition?
Lupus anticoagulant
A 44-year-old man presents for a follow-up visit for his known gastroesophageal reflux
disease. He has been taking a histamine-2-receptor antagonist twice a day. He continues
to have symptoms at least three times per week. Which of the following is the next best
therapy?
Omeprazole
A 59-year-old woman presents to the clinic reporting numbness in her hands and around
her mouth, as well as muscle cramps, fatigue, and intermittent hoarseness. Her medical
3|Page
