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BIOL 3306 - Exam 2 UH Zufall & Frankino questions with answers

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BIOL 3306 - Exam 2 UH Zufall & Frankino questions with answers

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BIOL 3306 - Exam 2 UH Zufall &
|\ |\ |\ |\ |\ |\ |\ |\




Frankino questions with answers |\ |\ |\




Evolutionary Genomics - CORRECT ANSWERS ✔✔The study of how
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changes in the content and organization of genomes have
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contributed to the diversity of life on earth
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Evolutionary Genomics made possibly by - CORRECT ANSWERS
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✔✔Technology of genomic sequencing |\ |\ |\




1976: First complete genome sequenced - CORRECT ANSWERS
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✔✔-MS2, an RNA virus |\ |\ |\




-genome size: 3569 nucleotides
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1977: First DNA genome sequenced - CORRECT ANSWERS ✔✔-phi
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X 174, a DNA virus
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-genome size: 5386 |\ |\




1995: First bacterial genome sequenced - CORRECT ANSWERS ✔✔-
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Haemophilus influenzae |\




-genome size: 1,830,140 bp
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1996: First eukaryotes sequenced - CORRECT ANSWERS ✔✔-
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Saccharomyces cerivisiae |\




-genome size: 12 million bp
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, 1998: First multicellular genome sequenced - CORRECT ANSWERS
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✔✔-Caenorhabditis elegans |\




-genome size: 100 million bp |\ |\ |\ |\




Human genome sequence completed in - CORRECT ANSWERS ✔✔-
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2001
-3100 million bp |\ |\




K-value paradox - CORRECT ANSWERS ✔✔Morphological
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complexity does not correlate with chromosome number |\ |\ |\ |\ |\ |\




C-value paradox - CORRECT ANSWERS ✔✔Morphological
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complexity does not correlate with genome size |\ |\ |\ |\ |\ |\




G-value paradox - CORRECT ANSWERS ✔✔Morphological
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complexity does not correlate with number of genes |\ |\ |\ |\ |\ |\ |\




dn - CORRECT ANSWERS ✔✔Rate of nonsynonymous substitutions
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per nonsynonymous sites
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d2 - CORRECT ANSWERS ✔✔Rate of synonymous substitutions per
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synonymous site |\




If dn/ds = 1 - CORRECT ANSWERS ✔✔Most nonsynonymous
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mutations are neutral (and are lost or fixed due to genetic drift)
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