Test BankFor Abrams’ Clinical Drug Therapy Ra
n n n n n n n
ionales for Nursing Practice 12th Edition (Version
n n n n n n
2023/2024) Geralyn Frandsen ISBN/ISSN 978197
n n n n
5136130.
, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
n n n n n n n n
1. A woman diagnosed with obsessive–
n n n n
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the e
n n n n n n n n n n n
xpected effect for this prescription? n n n n
A. Curative effect on symptoms n n n
B. Systemic effect on symptoms n n n
C. Local effect on symptoms n n n
D. Parenteral effect on symptoms n n n
ANS: B n
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the bl
n n n n n n n n n n n n n n
oodstream to their sites of action in various body tissues, and eventually eliminated from the bod
n n n n n n n n n n n n n n n
y. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will
n n n n n n n n n n n n n n n n
control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and lo
n n n n n n n n n n n n n n n n
cal anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administere
n n n n n n n n n n n n n
d parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intraven
n n n n n n n n n
ously.
PTS: 1 REF: p. 3, Introduction OBJ: 1 n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
GRADESBOOST.COM
n
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
n
n n n n n n n n n n n n
n
substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
n haOt Mi s another name for this type of me
.C n n n n n n n n n n n
n
dication?
n
A. Synthetic drug
n
n
n
B. Semisynthetic drug n
n
C. Biotechnology drug
n
n
n
D. Prototype drug n
n
n
ANS: B n
n
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
n
n n n n n n n n n n n
have been chemically modified. Synthetic drugs are more standardized in their chemical charact
n n n n n n n n n n n n
eristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechnol
n n n n n n n n n n n n n
ogy drugs involve manipulating DNA and RNA and recombining genes into hybrid molecules t
n n n n n n n n n n n n n
hat can be inserted into living organisms. Prototype drugs are the first drug of a particular group t
n n n n n n n n n n n n n n n n n
o be developed.
n n
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
3. Which classification applies to morphine?
n n n n
A. Central nervous system depressant n n n
B. Central nervous system stimulant n n n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
, GRADESBOOST.COM
C. Anti-inflammatory
D. Antihypertensive
ANS: A n
Rationale: Drugs are classified according to their effects on particular body systems, their thera
n n n n n n n n n n n n n
peutic uses, and their chemical characteristics. Morphine is classified as a central nervous syste
n n n n n n n n n n n n n
m depressant and will produce this effect in the client. A central nervous system stimulant increa
n n n n n n n n n n n n n n n
ses attention and raises mood. An anti-
n n n n n n
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antihy
n n n n n n n n n n n n n
pertensive agent reduces blood pressure. n n n n
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
n n 1 n n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Remember n NOT: Multiple Choice n n n n
4. A client is administered amoxicillin. The generic name of this medication belongs to which dru
n n n n n n n n n n n n n n
g group?
n
A. Selective serotonin reuptake inhibitors n n n
B. Diuretics
C. Penicillins
D. ACE inhibitors n
GRADESBOOST.COM
ANS: C
n
n
Rationale: The generic nameGRADESBOOST.COM
often indicates the drug group (e.g., drugs with generic names endi
n
n n n n n n n n n n n n n n
n
ng in “cillin” are penicillins). Selective serotonin reuptake inhibitors are medications that have a
n n n n n n n n n n n n n
n
ntidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medicatio
n
n n n n n n n n n n n n n
n
ns that increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor
n n n n n n n n n n n n n n n
n
is the broad classification for the angiotensin receptor blockers, not the generic name.
n n n n n n n n n n n n n
n
n
n
PTS: 1 REF: p. 3, Drug Names OBJ: 2 n n n
n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
n
n n n n n n n n
n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand n NOT: Multiple Choice n n n n
5. The administration of diphenhydramine is regulated by which U.S. government agency?
n n n n n n n n n n
A. Public Health Service n n
B. Federal Trade Commission n n
C. Occupational Safety and Health Administration n n n n
D. Food and Drug Administration n n n n
ANS: D n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
, GRADESBOOST.COM
Rationale: The Food and Drug Administration approves drugs for over-the-
n n n n n n n n n
counter availability, including the transfer of drugs from prescription to OTC status, and may re
n n n n n n n n n n n n n n
quire clinical trials to determine the safety and effectiveness of OTC use. The Public Health Ser
n n n n n n n n n n n n n n n
vice is regulated by the state to maintain the health of individual citizens of the state. The Federa
n n n n n n n n n n n n n n n n n
l Trade Commission regulates imports and exports throughout the nation. The Occupational Saf
n n n n n n n n n n n n
ety and Health Administration regulates safety within the workplace.
n n n n n n n n
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
n n n n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
6. In the U.S., the administration of anabolic steroids is regulated by which law?
n n n n n n n n n n n n
A. The Food, Drug, and Cosmetic Act of 1938
n n n n n n n
B. The Comprehensive Drug Abuse Prevention and Control Act
n n n n n n n
C. The Harrison Narcotic Act n n n
D. The Sherley Amendment n n
ANS: B n
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manufact
n n n n n n n n n n n
ure and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids.
n n n n n n n n n n n
The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsibili
n n n n n n n n n n n n n n
ties, giving the FDA control over drug safety. The Harrison Narcotic Act restricted the importati
GRADESBOOST.COM
n n n n n n n n n n n n n n
on, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs that the act d e f i Gn eR
n
n n n n n n n n n n n n n n n
n
d Aa Ds E
naSrcBoO
tiO
csSTh.eCSOhM
.T erley Amendment of 1912 prohibited fraudulent claims of drug effectiven
n
n n n n n n n n n n n
n
ess.
n
n
PTS: 1 REF:
n
n
p. 4, Prescription and Nonprescription Drugs OBJ: 3
n n n n n n
n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
n
n n n n n n n n
n
KEY: Integrated Process: Nursing Process
n n n n
n
BLM: Cognitive Level: Remember NOT: Multiple Choice
n
n n n n n
7. A nurse is responsible for maintaining an accurate count and record of the controlled substan
n n n n n n n n n n n n n n
ces on the nursing division. This nursing action is regulated by which U.S. law or agency?
n n n n n n n n n n n n n n n
A. The Food, Drug, and Cosmetic Act of 1938
n n n n n n n
B. The Public Health Service n n n
C. The Drug Enforcement Administration
n n n
D. The Sherley Amendment n n n
ANS: C n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
n n n n n n n
ionales for Nursing Practice 12th Edition (Version
n n n n n n
2023/2024) Geralyn Frandsen ISBN/ISSN 978197
n n n n
5136130.
, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
n n n n n n n n
1. A woman diagnosed with obsessive–
n n n n
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the e
n n n n n n n n n n n
xpected effect for this prescription? n n n n
A. Curative effect on symptoms n n n
B. Systemic effect on symptoms n n n
C. Local effect on symptoms n n n
D. Parenteral effect on symptoms n n n
ANS: B n
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the bl
n n n n n n n n n n n n n n
oodstream to their sites of action in various body tissues, and eventually eliminated from the bod
n n n n n n n n n n n n n n n
y. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will
n n n n n n n n n n n n n n n n
control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and lo
n n n n n n n n n n n n n n n n
cal anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administere
n n n n n n n n n n n n n
d parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intraven
n n n n n n n n n
ously.
PTS: 1 REF: p. 3, Introduction OBJ: 1 n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
GRADESBOOST.COM
n
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
n
n n n n n n n n n n n n
n
substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
n haOt Mi s another name for this type of me
.C n n n n n n n n n n n
n
dication?
n
A. Synthetic drug
n
n
n
B. Semisynthetic drug n
n
C. Biotechnology drug
n
n
n
D. Prototype drug n
n
n
ANS: B n
n
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
n
n n n n n n n n n n n
have been chemically modified. Synthetic drugs are more standardized in their chemical charact
n n n n n n n n n n n n
eristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechnol
n n n n n n n n n n n n n
ogy drugs involve manipulating DNA and RNA and recombining genes into hybrid molecules t
n n n n n n n n n n n n n
hat can be inserted into living organisms. Prototype drugs are the first drug of a particular group t
n n n n n n n n n n n n n n n n n
o be developed.
n n
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
3. Which classification applies to morphine?
n n n n
A. Central nervous system depressant n n n
B. Central nervous system stimulant n n n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
, GRADESBOOST.COM
C. Anti-inflammatory
D. Antihypertensive
ANS: A n
Rationale: Drugs are classified according to their effects on particular body systems, their thera
n n n n n n n n n n n n n
peutic uses, and their chemical characteristics. Morphine is classified as a central nervous syste
n n n n n n n n n n n n n
m depressant and will produce this effect in the client. A central nervous system stimulant increa
n n n n n n n n n n n n n n n
ses attention and raises mood. An anti-
n n n n n n
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antihy
n n n n n n n n n n n n n
pertensive agent reduces blood pressure. n n n n
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
n n 1 n n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Remember n NOT: Multiple Choice n n n n
4. A client is administered amoxicillin. The generic name of this medication belongs to which dru
n n n n n n n n n n n n n n
g group?
n
A. Selective serotonin reuptake inhibitors n n n
B. Diuretics
C. Penicillins
D. ACE inhibitors n
GRADESBOOST.COM
ANS: C
n
n
Rationale: The generic nameGRADESBOOST.COM
often indicates the drug group (e.g., drugs with generic names endi
n
n n n n n n n n n n n n n n
n
ng in “cillin” are penicillins). Selective serotonin reuptake inhibitors are medications that have a
n n n n n n n n n n n n n
n
ntidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medicatio
n
n n n n n n n n n n n n n
n
ns that increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor
n n n n n n n n n n n n n n n
n
is the broad classification for the angiotensin receptor blockers, not the generic name.
n n n n n n n n n n n n n
n
n
n
PTS: 1 REF: p. 3, Drug Names OBJ: 2 n n n
n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
n
n n n n n n n n
n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand n NOT: Multiple Choice n n n n
5. The administration of diphenhydramine is regulated by which U.S. government agency?
n n n n n n n n n n
A. Public Health Service n n
B. Federal Trade Commission n n
C. Occupational Safety and Health Administration n n n n
D. Food and Drug Administration n n n n
ANS: D n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
, GRADESBOOST.COM
Rationale: The Food and Drug Administration approves drugs for over-the-
n n n n n n n n n
counter availability, including the transfer of drugs from prescription to OTC status, and may re
n n n n n n n n n n n n n n
quire clinical trials to determine the safety and effectiveness of OTC use. The Public Health Ser
n n n n n n n n n n n n n n n
vice is regulated by the state to maintain the health of individual citizens of the state. The Federa
n n n n n n n n n n n n n n n n n
l Trade Commission regulates imports and exports throughout the nation. The Occupational Saf
n n n n n n n n n n n n
ety and Health Administration regulates safety within the workplace.
n n n n n n n n
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
n n n n n n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety n n n n n n n n
KEY: Integrated Process: Nursing Process
n n n n
BLM: Cognitive Level: Understand
n NOT: Multiple Choice n n n n
6. In the U.S., the administration of anabolic steroids is regulated by which law?
n n n n n n n n n n n n
A. The Food, Drug, and Cosmetic Act of 1938
n n n n n n n
B. The Comprehensive Drug Abuse Prevention and Control Act
n n n n n n n
C. The Harrison Narcotic Act n n n
D. The Sherley Amendment n n
ANS: B n
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manufact
n n n n n n n n n n n
ure and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids.
n n n n n n n n n n n
The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsibili
n n n n n n n n n n n n n n
ties, giving the FDA control over drug safety. The Harrison Narcotic Act restricted the importati
GRADESBOOST.COM
n n n n n n n n n n n n n n
on, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs that the act d e f i Gn eR
n
n n n n n n n n n n n n n n n
n
d Aa Ds E
naSrcBoO
tiO
csSTh.eCSOhM
.T erley Amendment of 1912 prohibited fraudulent claims of drug effectiven
n
n n n n n n n n n n n
n
ess.
n
n
PTS: 1 REF:
n
n
p. 4, Prescription and Nonprescription Drugs OBJ: 3
n n n n n n
n
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
n
n n n n n n n n n
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
n
n n n n n n n n
n
KEY: Integrated Process: Nursing Process
n n n n
n
BLM: Cognitive Level: Remember NOT: Multiple Choice
n
n n n n n
7. A nurse is responsible for maintaining an accurate count and record of the controlled substan
n n n n n n n n n n n n n n
ces on the nursing division. This nursing action is regulated by which U.S. law or agency?
n n n n n n n n n n n n n n n
A. The Food, Drug, and Cosmetic Act of 1938
n n n n n n n
B. The Public Health Service n n n
C. The Drug Enforcement Administration
n n n
D. The Sherley Amendment n n n
ANS: C n
GRADESBOOST.COM #1 TEST BANKS WEBSITE n n n n
