AP Biology: The Cell Cycle POGIL
1. How many phases are in the cell cycle? 4 phases
2. What is the order of the stages of a cell's life? G1, S, G2, M
3. During which phase does the size of the cell increase? G1 phase
4. During which phase does the number of cells increase? at the end of mitosis
5. Identify two ways that the growth of an organism can Organism growth requires
be accomplished through the events of the cell cycle. more cells to grow and
cells increase in size.
6. Cancer, the uncontrolled growth of cells, often results According to Model 1, G1
in a tumor, or mass of abnormal cells. Some cancerous phase is most likely affect-
tumors consist of many cells that are much smaller ed.
than normal. According to Model1, what part(s) of the
cell cycle is (are) most likely affected?
7. In Model 1, if the length of the arrow represents time, According to Model 1, the
then for those cancerous cells, what happens to the length of the arrow rep-
time that is necessary for the cell cycle? What impli- resents time. If some can-
cations might this have for doctors who are treating cerous cells are smaller
cancer patients? than normal than the time
spent to make a cancer-
ous cell would be short-
er. Cancerous cells divide
very quickly which makes it
hard for doctors to treat.
8. What is the key process of Gap 1? Cell division
9. What is the key process of Synthesis? DNA Replication(chromo-
somes duplicate)
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, AP Biology: The Cell Cycle POGIL
10. Model 2 presents cell cycle data for a typical human cell G is in Gap 1 and Gap 2, M
in culture. Use the phase names in Model 2 to label the is mitosis, S is Synthesis
G, M, and S phases in Model 1.
11. Looking at the third column of Model 2, compare the Model 2 showed that the
time spent in mitosis with the time spent in gap1, in time spent in mitosis is
human cells and describe any difference. shorter than Gap1, mitosis
takes 1/10 of the time in
Gap1.
12. Imagine 100 cells were chosen randomly fro a tissue Given 100 randomly cho-
sample and examined under a microscope. In which sen cells, one would ex-
phase of the cell cycle would you expect to find the pect to find the largest
largest number of cells? Explain. number of cells in G1
phase because cells spend
most of their time growing
before making new cells.
13. Looking again at Model 2, compare the amount of DNA Comparing the amount
at the beginning and at the end of synthesis. Why did of DNA from G1 to end
the amount of DNA change? of synthesis, the amount
of DNA doubled because
DNA replicated.
14. What is the key process for Synthesis in Model 2? Replication (chromosome
duplication)
15. Cyto = cell, kinesis = cutting. What do you think takes The cell gets split in half
place during cytokinesis? during cytokinesis.
16. Other than cytokinesis, what else occurs during the During mitosis phase, cy-
mitosis phase? Hint: Consider the sets of DNA in each tokinesis occurs, DNA is
cell.
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1. How many phases are in the cell cycle? 4 phases
2. What is the order of the stages of a cell's life? G1, S, G2, M
3. During which phase does the size of the cell increase? G1 phase
4. During which phase does the number of cells increase? at the end of mitosis
5. Identify two ways that the growth of an organism can Organism growth requires
be accomplished through the events of the cell cycle. more cells to grow and
cells increase in size.
6. Cancer, the uncontrolled growth of cells, often results According to Model 1, G1
in a tumor, or mass of abnormal cells. Some cancerous phase is most likely affect-
tumors consist of many cells that are much smaller ed.
than normal. According to Model1, what part(s) of the
cell cycle is (are) most likely affected?
7. In Model 1, if the length of the arrow represents time, According to Model 1, the
then for those cancerous cells, what happens to the length of the arrow rep-
time that is necessary for the cell cycle? What impli- resents time. If some can-
cations might this have for doctors who are treating cerous cells are smaller
cancer patients? than normal than the time
spent to make a cancer-
ous cell would be short-
er. Cancerous cells divide
very quickly which makes it
hard for doctors to treat.
8. What is the key process of Gap 1? Cell division
9. What is the key process of Synthesis? DNA Replication(chromo-
somes duplicate)
1/6
, AP Biology: The Cell Cycle POGIL
10. Model 2 presents cell cycle data for a typical human cell G is in Gap 1 and Gap 2, M
in culture. Use the phase names in Model 2 to label the is mitosis, S is Synthesis
G, M, and S phases in Model 1.
11. Looking at the third column of Model 2, compare the Model 2 showed that the
time spent in mitosis with the time spent in gap1, in time spent in mitosis is
human cells and describe any difference. shorter than Gap1, mitosis
takes 1/10 of the time in
Gap1.
12. Imagine 100 cells were chosen randomly fro a tissue Given 100 randomly cho-
sample and examined under a microscope. In which sen cells, one would ex-
phase of the cell cycle would you expect to find the pect to find the largest
largest number of cells? Explain. number of cells in G1
phase because cells spend
most of their time growing
before making new cells.
13. Looking again at Model 2, compare the amount of DNA Comparing the amount
at the beginning and at the end of synthesis. Why did of DNA from G1 to end
the amount of DNA change? of synthesis, the amount
of DNA doubled because
DNA replicated.
14. What is the key process for Synthesis in Model 2? Replication (chromosome
duplication)
15. Cyto = cell, kinesis = cutting. What do you think takes The cell gets split in half
place during cytokinesis? during cytokinesis.
16. Other than cytokinesis, what else occurs during the During mitosis phase, cy-
mitosis phase? Hint: Consider the sets of DNA in each tokinesis occurs, DNA is
cell.
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