Lippincott Illustrated Reviews
Pharmacology - CNS
Which one of the following statements is correct regarding
benzodiazepines?
A. Benzodiazepines directly open chloride ^&^$*%&*&
channels. *%&*&*%&
B. Benzodiazepines show analgesic actions. *&*&*%&*&
*%*&*(%&*
C. Clinical improvement of anxiety requires 2 to 4 &*&*%&*&*
weeks of treatment with benzodiazepines. %&*&*%&*
D. All benzodiazepines have some sedative effects. &*%&*%&*
&*%&*%
E. Benzodiazepines, like other CNS depressants,
readily produce general anesthesia. - ANSWER: D
Which one of the following is a short-acting hypnotic?
A. Phenobarbital.
B. Diazepam.
C. Chlordiazepoxide.
D. Triazolam.
E. Flurazepam. - ANSWER: D
Which one of the following statements is correct regarding the
anxiolytic and hypnotic agents?
A. Phenobarbital shows analgesic properties.
B. Diazepam and phenobarbital induce the cytochrome
P450 enzyme system.
C. Phenobarbital is useful in the treatment of acute
intermittent porphyria.
D. Phenobarbital induces respiratory depression, which
is enhanced by the consumption of ethanol.
E. Buspirone has actions similar to those of the
benzodiazepines. - ANSWER: D
, Lippincott Illustrated Reviews
Pharmacology - CNS
A 45-year-old man who has been injured in a car accident is brought
into the emergency room. His blood alcohol level on admission is 275
mg/dL. Hospital records show a prior hospitalization for alcohol- ^&^$*%&*&
related seizures. His wife confirms that he has been drinking heavily *%&*&*%&
for 3 weeks. What treatment should be provided to the patient if he*&*&*%&*&
*%*&*(%&*
goes into withdrawal? &*&*%&*&*
A. None. %&*&*%&*
B. Lorazepam. &*%&*%&*
&*%&*%
C. Pentobarbital.
D. Phenytoin.
E. Buspirone. - ANSWER: B
Which one of the following is a short-acting hypnotic and better for
sleep induction compared to sleep maintenance?
A. Temazepam.
B. Flurazepam.
C. Zaleplon.
D. Buspirone.
E. Escitalopram. - ANSWER: C
Which of the following agents has a rapid anxiolytic effect and would
be best for the acute management of anxiety?
A. Buspirone.
B. Venlafaxine.
C. Lorazepam.
D. Escitalopram.
E. Duloxetine. - ANSWER: C
Which of the following sedative-hypnotic agents utilizes melatonin
receptor agonism as the mechanism of action to induce sleep?
A. Zolpidem.
Pharmacology - CNS
Which one of the following statements is correct regarding
benzodiazepines?
A. Benzodiazepines directly open chloride ^&^$*%&*&
channels. *%&*&*%&
B. Benzodiazepines show analgesic actions. *&*&*%&*&
*%*&*(%&*
C. Clinical improvement of anxiety requires 2 to 4 &*&*%&*&*
weeks of treatment with benzodiazepines. %&*&*%&*
D. All benzodiazepines have some sedative effects. &*%&*%&*
&*%&*%
E. Benzodiazepines, like other CNS depressants,
readily produce general anesthesia. - ANSWER: D
Which one of the following is a short-acting hypnotic?
A. Phenobarbital.
B. Diazepam.
C. Chlordiazepoxide.
D. Triazolam.
E. Flurazepam. - ANSWER: D
Which one of the following statements is correct regarding the
anxiolytic and hypnotic agents?
A. Phenobarbital shows analgesic properties.
B. Diazepam and phenobarbital induce the cytochrome
P450 enzyme system.
C. Phenobarbital is useful in the treatment of acute
intermittent porphyria.
D. Phenobarbital induces respiratory depression, which
is enhanced by the consumption of ethanol.
E. Buspirone has actions similar to those of the
benzodiazepines. - ANSWER: D
, Lippincott Illustrated Reviews
Pharmacology - CNS
A 45-year-old man who has been injured in a car accident is brought
into the emergency room. His blood alcohol level on admission is 275
mg/dL. Hospital records show a prior hospitalization for alcohol- ^&^$*%&*&
related seizures. His wife confirms that he has been drinking heavily *%&*&*%&
for 3 weeks. What treatment should be provided to the patient if he*&*&*%&*&
*%*&*(%&*
goes into withdrawal? &*&*%&*&*
A. None. %&*&*%&*
B. Lorazepam. &*%&*%&*
&*%&*%
C. Pentobarbital.
D. Phenytoin.
E. Buspirone. - ANSWER: B
Which one of the following is a short-acting hypnotic and better for
sleep induction compared to sleep maintenance?
A. Temazepam.
B. Flurazepam.
C. Zaleplon.
D. Buspirone.
E. Escitalopram. - ANSWER: C
Which of the following agents has a rapid anxiolytic effect and would
be best for the acute management of anxiety?
A. Buspirone.
B. Venlafaxine.
C. Lorazepam.
D. Escitalopram.
E. Duloxetine. - ANSWER: C
Which of the following sedative-hypnotic agents utilizes melatonin
receptor agonism as the mechanism of action to induce sleep?
A. Zolpidem.
