NR546-FINAL EXAM-PEARL QUESTIONS
AND ANSWERS 100% CORRECT!!!
, First line treatment for depression - ANSWER SSRIs
Common side effect of SSRIs - ANSWER sexual dysfunction
rapid cycling bipolar disorder - ANSWER Minimum of 4 episodes a year
Goal of antidepressant therapy - ANSWER complete remission of symptoms
Serotonin GI effects - ANSWER Due to the fact that 90% of 5HT receptors are located
in GI tract
best tolerated SSRI - ANSWER Escitalopram (Lexapro) also has fewest CYP
interactions
Lithium levels - ANSWER Can be increased by NSAIDS and ACE inhibitors
Can be decreased by caffeine and mania
Unaffected by amiloride, furosemide, and sulindac
Lithium purpose - ANSWER Effective treatment for manic episodes, to prevent
reoccurrence and to a lower degree is effective in depressive episodes
Lamotrigine - ANSWER Well tolerated except for the propensity to cause a rash
Monoamines - ANSWER dopamine, norepinephrine, serotonin
Lamotrigine - ANSWER Is a mood stabilizer
Lithium - ANSWER Well established to prevent suicide in clients with mood disorders
Lithium - ANSWER Has a narrow therapeutic window and requires law draws
1st line treatment for OCD - ANSWER SSRIs are first line. Benzodiazepines are not!!!
Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin, and MDMA -
ANSWER Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly
5HT1A and 5HT2C) and at other neurotransmitter systems, and MDMA in particular
also blocks the serotonin transporter (SERT)
AND ANSWERS 100% CORRECT!!!
, First line treatment for depression - ANSWER SSRIs
Common side effect of SSRIs - ANSWER sexual dysfunction
rapid cycling bipolar disorder - ANSWER Minimum of 4 episodes a year
Goal of antidepressant therapy - ANSWER complete remission of symptoms
Serotonin GI effects - ANSWER Due to the fact that 90% of 5HT receptors are located
in GI tract
best tolerated SSRI - ANSWER Escitalopram (Lexapro) also has fewest CYP
interactions
Lithium levels - ANSWER Can be increased by NSAIDS and ACE inhibitors
Can be decreased by caffeine and mania
Unaffected by amiloride, furosemide, and sulindac
Lithium purpose - ANSWER Effective treatment for manic episodes, to prevent
reoccurrence and to a lower degree is effective in depressive episodes
Lamotrigine - ANSWER Well tolerated except for the propensity to cause a rash
Monoamines - ANSWER dopamine, norepinephrine, serotonin
Lamotrigine - ANSWER Is a mood stabilizer
Lithium - ANSWER Well established to prevent suicide in clients with mood disorders
Lithium - ANSWER Has a narrow therapeutic window and requires law draws
1st line treatment for OCD - ANSWER SSRIs are first line. Benzodiazepines are not!!!
Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin, and MDMA -
ANSWER Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly
5HT1A and 5HT2C) and at other neurotransmitter systems, and MDMA in particular
also blocks the serotonin transporter (SERT)
