CMSRN Study Guide Questions and Answers Latest 2025/2026
(100% Rationalized Answers)
1. Antidiuretic hormone (ADH) is synthesized in the:
A. Hypothalamus
B. Pituitary gland
C. Pineal gland
D. Thalamus: A. Hypothalamus
Antidiuretic hormone is an example oƒ a neuroendocrine hormone; it has com- ponents oƒ bo
the endocrine and the nervous system. It is synthesized in the hypothalamus and travels alon
axons that terminate adjacent to capillaries in the posterior pituitary.
2. The physician has ordered chlorpropamide (Diabinese) to treat a patient with
central diabetes insipidus. The nurse is aware:
A. Contraindications include heart disease and renal insuƒƒiciency
B. Usual dosing in diabetes insipidus is 100 mg daily
C. This medication is an oral hypoglycemic
D. This medication suppresses the release oƒ vasopressin: C. This medication is an oral
hypoglycemic
Chlorpropamide is an oral hypoglycemic (ƒirst generation sulƒonylurea). It lowers blood
glucose levels by enhancing pancreatic beta-cell insulin secretion (primary use). It also
potentiates the action (not suppresses the release) oƒ small or residual amounts oƒ circulatin
vasopressin (ADH), making it useƒul in treating diabetes insipidus (hyposecretion oƒ ADH).
Usual dosing in diabetes insipidus is 125-500 mg daily.
Contraindications include liver disease (not heart disease) and renal insuƒƒiciency.
3. In patients with diabetes mellitus who have normal renal ƒunction, protein intake
should be:
A. 30%-35% oƒ daily caloric intake
B. 20%-25% oƒ daily caloric intake
C. 15%-20% oƒ daily caloric intake
1/
15
, D. 5%-10% oƒ daily caloric intake: C. 15%-20% oƒ daily caloric intake
In patients with diabetes mellitus, who have normal renal ƒunction, there is little evidence to
suggest that usual protein intake (15-20% oƒ daily caloric intake) should be modiƒied. With
evidence oƒ neuropathy, it may be necessary to restrict protein to the adult.
4. You are caring ƒor a patient with Type 2 diabetes mellitus who has been prescribed
glipizide (Glucotrol), an oral antidiabetic agent, ƒor trouble control- ling blood glucose
levels through diet and exercise alone. Which medication
2/
15
(100% Rationalized Answers)
1. Antidiuretic hormone (ADH) is synthesized in the:
A. Hypothalamus
B. Pituitary gland
C. Pineal gland
D. Thalamus: A. Hypothalamus
Antidiuretic hormone is an example oƒ a neuroendocrine hormone; it has com- ponents oƒ bo
the endocrine and the nervous system. It is synthesized in the hypothalamus and travels alon
axons that terminate adjacent to capillaries in the posterior pituitary.
2. The physician has ordered chlorpropamide (Diabinese) to treat a patient with
central diabetes insipidus. The nurse is aware:
A. Contraindications include heart disease and renal insuƒƒiciency
B. Usual dosing in diabetes insipidus is 100 mg daily
C. This medication is an oral hypoglycemic
D. This medication suppresses the release oƒ vasopressin: C. This medication is an oral
hypoglycemic
Chlorpropamide is an oral hypoglycemic (ƒirst generation sulƒonylurea). It lowers blood
glucose levels by enhancing pancreatic beta-cell insulin secretion (primary use). It also
potentiates the action (not suppresses the release) oƒ small or residual amounts oƒ circulatin
vasopressin (ADH), making it useƒul in treating diabetes insipidus (hyposecretion oƒ ADH).
Usual dosing in diabetes insipidus is 125-500 mg daily.
Contraindications include liver disease (not heart disease) and renal insuƒƒiciency.
3. In patients with diabetes mellitus who have normal renal ƒunction, protein intake
should be:
A. 30%-35% oƒ daily caloric intake
B. 20%-25% oƒ daily caloric intake
C. 15%-20% oƒ daily caloric intake
1/
15
, D. 5%-10% oƒ daily caloric intake: C. 15%-20% oƒ daily caloric intake
In patients with diabetes mellitus, who have normal renal ƒunction, there is little evidence to
suggest that usual protein intake (15-20% oƒ daily caloric intake) should be modiƒied. With
evidence oƒ neuropathy, it may be necessary to restrict protein to the adult.
4. You are caring ƒor a patient with Type 2 diabetes mellitus who has been prescribed
glipizide (Glucotrol), an oral antidiabetic agent, ƒor trouble control- ling blood glucose
levels through diet and exercise alone. Which medication
2/
15
