/\ /\ /\ /\ /\
WIT VERIFIED ANSWERS /\ /\
COPD Stage I - CORRECT ANSWERS ✔✔MILD
/\ /\ /\ /\ /\ /\
FEV1/FVC <70% /\
FEV1</80%
*Chronic cough/sputum production /\ /\
*Pt unaware lung function is abnormal
/\ /\ /\ /\ /\
COPD Stage II - CORRECT ANSWERS ✔✔MODERATE
/\ /\ /\ /\ /\ /\
FEV1/FVC <70% /\
FEV1 50-80% /\
SOB with exertion
/\ /\
Cough and sputum production present
/\ /\ /\ /\
COPD Stage III - CORRECT ANSWERS ✔✔SEVERE
/\ /\ /\ /\ /\ /\
FEV1/FVC < 70% /\ /\
FEV1 30-50% /\
Greater SOB /\
Reduced exercise capacity /\ /\
Fatigue
,Repeated exacerbations with impact on QOL
/\ /\ /\ /\ /\
COPD Stage IV - CORRECT ANSWERS ✔✔VERY SEVERE
/\ /\ /\ /\ /\ /\ /\
FEV1/FVC<70%
FEV1<30%
Resp. Failure/\
Cor Pulmonale (elevation of JVP and pitting ankle edema)
/\ /\ /\ /\ /\ /\ /\ /\
QOL very impaired
/\ /\
Exacerbations may be life threatening /\ /\ /\ /\
How does FEV1 decrease? - CORRECT ANSWERS ✔✔Inflammation
/\ /\ /\ /\ /\ /\ /\
Narrowing of peripheral airways /\ /\ /\
Airway collapse in severe emphysema
/\ /\ /\ /\
COPD diagnosis? - CORRECT ANSWERS ✔✔SPIROMETRY is key
/\ /\ /\ /\ /\ /\ /\
Primarily Inflammatory with superimposed bronchospasm - CORRECT
/\ /\ /\ /\ /\ /\ /\
ANSWERS ✔✔Asthma /\
Most common chronic respiratory disorder among all age groups -
/\ /\ /\ /\ /\ /\ /\ /\ /\ /\
CORRECT ANSWERS ✔✔Asthma /\ /\
Atophy - CORRECT ANSWERS ✔✔exaggerated IgE mediated immune
/\ /\ /\ /\ /\ /\ /\ /\
response; all atophic disorders are type I hypersensitivity disorders
/\ /\ /\ /\ /\ /\ /\ /\
, Type I hypersensitivity reaction - CORRECT ANSWERS ✔✔Immediate
/\ /\ /\ /\ /\ /\ /\ /\
hypersensitivity /\
IgE-mediated
Antigen binds to IgE that is bound to tissue mast cells and blood basophils,
/\ /\ /\ /\ /\ /\ /\ /\ /\ /\ /\ /\ /\ /\
triggering release of preformed mediators (histamine, proteases, chemotactic
/\ /\ /\ /\ /\ /\ /\ /\
factors) and synthesis of other mediators (prostaglandins, leukotrienes,
/\ /\ /\ /\ /\ /\ /\ /\
platelet-activating factor, cytokines) /\ /\
-causes vasodilation, increased cap. permeability, mucus hypersecretion
/\ /\ /\ /\ /\ /\
**atopic disorders (allergic asthma, rhinitis, conjunctivitis), anaphylaxis,
/\ /\ /\ /\ /\ /\ /\
some cases of angioedema, urticarial, and latex and some food allergies
/\ /\ /\ /\ /\ /\ /\ /\ /\ /\
**Develop <1h after exposure to antigen /\ /\ /\ /\ /\
Allergic triad of symptoms - CORRECT ANSWERS ✔✔allergies, eczema,
/\ /\ /\ /\ /\ /\ /\ /\ /\
and asthma
/\
Samter's Triad - CORRECT ANSWERS ✔✔Nasal polyps, asthma, and ASA
/\ /\ /\ /\ /\ /\ /\ /\ /\ /\
allergy
Most common symptom of asthma - CORRECT ANSWERS ✔✔wheezing
/\ /\ /\ /\ /\ /\ /\ /\
Common only symptom of asthma? - CORRECT ANSWERS ✔✔Cough
/\ /\ /\ /\ /\ /\ /\ /\
-can often delay dx of asthma
/\ /\ /\ /\ /\
AKA cough variant asthma
/\ /\ /\