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HESI Pharmacology Practice Test – 2025/2026 A+ Verified Questions & Answers

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Boost your performance on the HESI Pharmacology Exam with this fully updated 2025/2026 practice test, featuring 100% verified and accurate answers. This exam prep guide covers all essential pharmacological concepts tested on HESI, including drug classifications, therapeutic uses, mechanisms of action, adverse effects, safe dosage calculations, and NCLEX-style application questions. Each question is carefully crafted to reflect the real HESI format and rigor, helping you sharpen both your clinical judgment and test-taking skills. With A+ rated content, this resource has been trusted by nursing students to secure high scores and prepare effectively for HESI success. Whether you're prepping for your course exam or gearing up for the NCLEX, this practice set provides the clarity and confidence needed to excel.

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HESI Pharmacology Practice Test Exam With
Questions and Answers All Answers 100% Verified
(Latest Update 2025/2026 RATED A+




HESI Pharmacology Practice Test Exam With
Questions and Answers All Answers 100% Verified
(Latest Update 2025/2026 RATED A+

,HESI Pharmacology Practice Test Exam With
Questions and Answers All Answers 100% Verified
(Latest Update 2025/2026 RATED A+




Following the administration of sublingual nitroglycerin to a client experiencing an acute anginal
attack, which assessment finding indicates to the nurse that the desired effect has been
achieved?
A. Client states chest pain is relieved
B. Client's pulse decreases from 120 to 90
C. Client's systolic blood pressure decreases from 180 to 90
D. Clients SaO2 level increases from 92% to 96% - CORRECT ANSWERS A. nitroglycerin
reduces mycocardial oxygen consumption which decreases ischemia and reduces chest pain


A client with hyperlipidemia recieves a prescription for niacin (niaspan). which client teaching is
most important for the nurse to provide
a. expected duration of flushing
b. symptoms of hyperglycemia
c. diets that minimize gi irritation
d. comfort measure for pruritis - CORRECT ANSWERS A. flushing of the face and neck,
lasting up to an hour, is a frequent reason for discontinuing niacin. inclusion of this effect in
clietn teaching may promote compliance in taking the med.


When assessing an adolescent who recently overdosed on acetaminophen (tylonel), it is most
important for the nurse to assess for pain in which area of the body
a. flank
b. abdomen
c. chest
d. head - CORRECT ANSWERS B. acetaminophen toxicisty an result in liver damage;
therefore, it is especially important for the nurse to assess for pain in the right upper quadrant of
the abdomen (which might indicated liver damage)

, HESI Pharmacology Practice Test Exam With
Questions and Answers All Answers 100% Verified
(Latest Update 2025/2026 RATED A+
A client is admitted to the coronary care unit with a medical diagnosis of acute myocardial
infarction. which medication prescription decreases both preload and afterload
a. nitroglycerin
b. propranolol
c. propranolol
d. captopril - CORRECT ANSWERS A. nitroglycerin is a nitrate that causes peripheral
vasodilation and decreases contractility, thereby decreasing both preload and afterload


A client is being treated for hyperthyroidism with propylthiouracil (PTU). The nurse knows that
the action of this drug is to
A. decrease the amount of the thyroid-stimulating hormone circulating in the blood
B. increase the amount of thyroid-stimulating hormone circulating in the blood
C. increase the amount of T4 and decrease the amount of T3 produced by the thyroid
D. inhibit synthesis of T3 and T4 by the thyroid gland - CORRECT ANSWERS D. PTU is an
adjunct therapy used to control hyperthyroidism by inhibiting production of thyroid hormones. It
is often prescribed in prep for thyroidectomy or radioactive iodine therapy


Which change in data indicates to the nurse the desired effect of the angiotensin II receptor
antagonist has been achieved
A. Dependent edema reduced form +3 to +1
B. Serum HDL increased from 35 to 55mg/dl
C. PUlse rate reduced from 150 to 90 beats/min
D. Blood pressure reducedf rom 160/90 to 130.80 - CORRECT ANSWERS D. angiotensin II
receptor antagonist (blocker), prescribed from treatment of HTN. The desired effect is a
decrease in blood pressure.


Which instructions should the nurse give to a female client who just recieved a prescription for
oral metronidazole (flagyl) for treatment of trichomonas vaginalis (select all that apply)
A. increase fluid intake, especially cranberry juice
B. Do not abruptly discontinue the medication; taper use
C. Check blood pressure daily to detect hypertension
D. Avoid drinking alcohol while taking this medication

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