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QUESTION 1
1. Select the neurotransmitter involved in obsessive-compulsive disorder
(OCD) in children and adolescents based on the common comorbidity of tic
A Norepinephrine
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B
GABA
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.
C
Dopamine
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.
D Acetylcholine
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Answer:
Dopamine
Obsessive-compulsive disorder (OCD) is linked to defects in the cortico-striatal- thalamic-
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cortical (CSTC) circuitry, which may be linked to neurotransmitter dysregulation
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-aminobutyric acid (GABA) are the main neurotransmitters throughout the CSTC.
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Compulsive behaviors linked to OCD are likely the product of a related dopaminergic reward
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system dysfunction. Continuous ventral striatum activation may lead to an undirected expectation
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of reward. Anxiety and a desire to fill the gap are caused by unfulfilled expectations.
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References
Richter, M. A., De Jesus, D. R., Hoppenbrouwers, S., Daigle, M., Deluce, J., Ravindran,
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L. N., ... & Daskalakis, Z. J. (2019). Evidence for cortical inhibitory and excitatory
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dysfunctioninobsessive compulsive disorder. Neuropsychopharmacology,37(5), 1144-
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1151.
Pittenger, C.,Krystal,J. H., &Coric,V. (2016).Glutamate-modulating drugsasnovel
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pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. j j j j j j j j
NeuroRx,3(1),69-81. j j
QUESTION 2
Answer:
NURS 6635 MIDTERM-PMHNP Newly Updated 2022/2023 Exam
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A B TCA and SSRI
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Opioid j
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analgesi C Beta-adrenergic
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cs . blockers
. D
Mood stabilizers
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Opioids analgesics
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Opioid analgesics are drugs that function on opioid receptors that are used to alleviate pain.
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Weak opioid analgesics are often used to describe compound analgesics that combine
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acetaminophen with low levels of codeine or tramadol. Opioid analgesics, which include
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oxycodone, hydrocodone, and codeine, can be used to relieve mild to extreme acute pain.
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Opioids are medications that are chemically similar to, but more potent than, the body's own pain
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relievers (endorphins). They operate by binding to receptors on cells, primarily in the brain, spinal cord,
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and gastrointestinal tract.
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References
Andrieu, G.,Amrouni, H., Robin, E., Carnaille, B., Wattier, J. M., Pattou, F., ... &
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Lebuffe, G. (2017). Analgesic efficacy of bilateral superficial cervical plexus block
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administered before thyroid surgery under general anaesthesia. British journal of
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anaesthesia, 99(4), 561-566. j j
Mangione, M.P.,& Crowley-Matoka, M. (2018). Improving pain management communication: how
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patients understand the terms "opioid" and "narcotic". Journal of general
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internal medicine, 23(9), 1336.
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points
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