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Summary part two- Anatomy physiology (AB_1176)

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Summary of part two of course anatomie en fysiologie at vrije universiteit amsterdam. 4 lectures summarised.

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Uploaded on
June 5, 2025
Number of pages
30
Written in
2023/2024
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Hc: Fysiologie van de vaten
Bloedvatenstelsel:
Functies: bloed brengt 02, voedingsstoffen en hormonen naar weefsels en voert
afvalstoffen af. Het bloed is ook een transportbaan waar cellen ‘vervoerd’ worden van
en naar de weefsels.

Functies van de capillairen:
- Macrocirculatie
o Grote arteries –> transport
- Microcirculatie
o Kleine arteries → regulatie
o Arteriolen → regulatie
o Capillairen → uitwisseling

Weerstand vaten: arteriolen
→ bepalen bloeddruk




Diastolische druk + (pulse pressure/ 3) = mean arterial pressure
→ pulse pressure is het verschil tss systolische en diastolische bloeddruk.

Verschil volume/ verschil druk = compliantie van een bloedvat (rekbaarheid)

,Wet van Poiseuille
Hoe kleiner de diameter hoe hoger de weerstand en des te minder flow




Arteriolen reguleren druk:

, Vlak voor capillaire bed zitten er allemaal sphincters (bepalen flow) → open en dicht
gaan




Op moment dat bloed van aorta verdeeld wordt over capilairen dan wordt de snelheid
minder → flow lager → lage druk in cappilairen

Bloeddruk regulerende systemen:
- Hart → cardiac output = hartfrequentie x slagvolume
- Nieren → renine: vochtregulatie
- Bloedvaten → vasoconstictrictie en dilatatie

Regulatie van bloeddruk:
- Lokale regulatie
- Centrale regulatie
o Endocrine (hormone) → lange termijn regulatie (duurt lang voordat je druk
kan reguleren maar zodra het gereguleert is blijft het ook lang zo)
o Neuronale → korte termijn regulatie
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