PHARMACOLOGY 11th EDITION BY GARDENHIRE/ALL
CHAPTERS S 1-23
,CH 01: Introduction to Respiratory Care Pharmacology
Gardenhire: Rau’s Respiratory Care Pharmacology, 11th Edition
MULTIPLE RESPONSES
1. The listing of a drug and the amount of drug are found in which part of a prescription?
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a. Superscription
b. Inscription
c. Subscription
d. Transcription (signature) d
PRECISE ANSWER:-B d
Reasoning :- d
>>>The superscription directs the registered pharmacist to take the drug listed and preparethe drug; the inscriptio
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n lists the name and quantity of the drug being prescribed; the subscriptionprovides directions to the registered pha
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rmacist for preparing the drug; and the transcription, or signature, is the information the registered pharmacist writ
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es on the label as instructions to the patient.
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REFERENCE: p. 7 d d
2. If generic substitution is permitted on a prescription:
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a. drug from only one manufacturer must be given.
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b. drug formulation may be changed by the registered pharmacist.
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c. any manufactured brand of the drug listed may be given.
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d. drug strength may be changed by the registered pharmacist.
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PRECISE ANSWER:-C d
Reasoning :- d
>>>A generic substitution allows any brand of a drug to be given, but the registered pharmacist may not change a
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drug formulation without specific permission from the prescribing physician. A physician can indicate to the regis
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tered pharmacist that generic substitution is permitted in the filling of the prescription. In such a case, the registere
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d pharmacist may provide any manufacturer’s version of the prescribed drug, rather than a specific brand. Howeve
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r, the registered pharmacist may not change thestrength of a drug without specific permission from the prescribing
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physician.
REFERENCE: p. 8 d d
3. The study of drug, including their origin, properties, and interactions with living organisms, is known as
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a. pharmacogenetics.
b. pharmacology.
c. therapeutics.
d. toxicology.
PRECISE ANSWER:-B d
Reasoning:-
>>>Pharmacogenetics is the study of the interrelationship of genetic differences and drug effects. Pharmacology is
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the study of drug (chemicals), including their origin, properties, and interactionswith living organisms.
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Therapeutics is the art of treating illness with drug. Toxicology is the study of toxic substances and theirpharmacolo
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gic actions, including antidotes and poison control.
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REFERENCE: p. 3 d d
4. The brand name given to a drug by a particular manufacturer is known as the drug’s
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a. chemical name. d
b. generic name. c.official name. d.trade name.
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PRECISE ANSWER:-D d
,Reasoning:-
>>>The chemical name indicates the drug’s chemical structure. The generic name is assignedby the United States
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, Adopted Name Council and is usually based loosely on the drug’s chemical structure. The official name isthe
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name given to the generic name once a drug becomes fully approved for general use and is admitted to the United
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States Pharmacopeia– d
National Formulary. The trade name is the brand, or proprietary, name given by a particular manufacturer. For exa
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mple, the generic drug albuterol is currently marketed by Schering-
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Plough as Proventil® and by GlaxoSmithKline as Ventolin®.
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REFERENCE: p. 5 d d
5. To find official information about drug (according to the FDA), you need to go to the
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a. Physician’s Desk Referenceerence (PDR). d d d
b. Basic & Clinical Pharmacology. d d d
c. United States Pharmacopeia–National Formulary (USP-NF). d d d d
d. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. d d d d d d d
PRECISE ANSWER:-C d
Reasoning:-
>>>Because the PDR is prepared by drug manufacturers themselves, it may be lacking in objectivity. Basic & Cli
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nical Pharmacology covers only general pharmacologic principles and drug classes. Goodman & Gilman’s The P
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harmacological Basis of Therapeutics covers only general pharmacologicprinciples and drug classes. The USP-
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NF is a book of standards containing information about drugs, dietary supplements, and medical devices. The U.
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S. Food and Drug Administration (FDA)considers this book the official standard for drug marketed in the United
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States.
REFERENCE: p. 5 d d
6. Drug may be obtained from which of the following sources?
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a. Plants
b. Animals
c. Minerals
d. Plants, animals, and minerals d d d
PRECISE ANSWER:-D d
Reasoning:-
>>>Drug may be obtained from plants (e.g., digitalis), animals (e.g., insulin), and minerals(e.g., magnesium sulfate)
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.
REFERENCE: p. 5 d d
7. The branch of the U.S. government responsible for the process of approving drug for clinical use is the
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a. USAN Council. d
b. FDA.
c. USP-NF.
d. PDR.
PRECISE ANSWER:-B d
Reasoning:-
>>>The United States Adopted Name (USAN) Council is responsible for assigning a generic name to a chemical t
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hat appears to have therapeutic use. The U.S. Food and Drug Administration (FDA) is responsible for the process o
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f approving drug for clinical use. The process by which a chemical movesfrom the status of a promising potential dr
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ug to one fully approved by the FDA for general clinical use is,on average, long, costly, and complex. Cost estimate
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s vary, but in the 1980s it took an average of 13 to 15 yearsfrom chemical synthesis to marketing approval by the FD
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A, with a cost of $350 million in the United States.
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The USP-NF is a bookd d d d
of standards for drugs, dietary supplements, and medical devices. The PDR is a source of druginformation prepared
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by drug manufacturers.
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