Science Medicine Psychiatry Debi is a 15-year-old girl who is currently symptoms
being treated for depression. Her parents B. The mean length of major depressive episode in adolescents is 4 months
NRNP 6665 Final Exam Test Questions have been very proactive and involved in C. 20 to 40% of adolescents who have major depressive disorder will develop
her care, and Debi has achieved remission bipolar I within 5 years
Leave the first rating 2 months after beginning treatment with a D. Adolescent-onset depression typically need long-term pharmacologic
combination of pharmacotherapy and management to prevent relapses
Save
cognitive behavioral therapy. While
counseling Debi's parents about important
issues in management, the PMHNP advises
that:
Students also studied
Brand: Valdoxan
-Melatonin multimodal (Mel-MM)
Flashcard sets Study guides Practice tests -Agonist at melatonergic 1 and melatonergic 2 receptors
Agomelatine
-Antagonist at 5HT2C receptors
-Not FDA approved: Rx for Depression, Generalized anxiety disorder
PHARM Q5 spiegel psychiatry psych psychotic disorders buzzes HPS Ch
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime
25 terms 900 terms 24 terms 24 terms
Amitriptyline (Elavil) Tricyclic antidepressant.
Treatment for depression. Atypical antipsychotic. "Dopamine stabilizer". Dopamine
supermeaghannbradl... Preview Gowri_Gouda2 Preview davidwmfranco1 Preview feli
Aripiprazole (Abilify) receptor antagonist in high concentration and also stimulates increase of dopamine
in low concentrations. Side effects: insomnia, akathisia.
Brexpiprazole (Rexulti) Treatment for depression. Atypical antipsychotic
Terms in this set (131) Antidepressant and smoking cessation aid, It can treat depression and help people
Bupropion (Wellbutrin) quit smoking. It can also prevent depression caused by seasonal affective disorder
(SAD).
Question 18: A. Dissociative disorders
Citalopram (Celexa) Antidepressant, SSRI: 20-40 mg qd.
Christine is a 9-year-old female who B. Post-traumatic stress disorder
presents for care after having been placed C. Impulse-control disorder -Serotonin reuptake inhibitor (S-RI)
in the local foster care system. She has D. Attachment disorder -Tricyclic antidepressant (TCA)
been in and out of foster care for the last 4 -Parent drug is a potent serotonin reuptake inhibitor
years after her parents were killed in an Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor
automobile accident. Christine has been -Increases serotonergic neurotransmission by blocking the serotonin reuptake pump
placed in a variety of homes and residential (transporter), -Desensitization of serotonin receptors, especially serotonin 1A
care facilities. The PMHNP recognizes that receptors
Christine is at high risk for: -Increases noradrenergic neurotransmission by blocking the norepinephrine
reuptake pump (transporter), -Desensitization of beta adrenergic receptors
Question 7: A. Caylee is at high risk for suicide and precautions should be taken
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex
Caylee is a 5-year-old girl who is referred B. The hallucinations are consistent with brief psychotic disorder or schizophrenia Clomipramine (Anafranil)
-Lacks dopamine transporters
for evaluation by child protective services. C. The history and reported symptoms are typical of depressive disorder in young
-Increases dopamine neurotransmission in this part of the brain
She was recently removed from her children
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10
biological family and placed in foster care, D. This is a common situation when prepubertal children are removed from the
and older)
as her home environment was reportedly biological parents regardless of how dysfunctional they are
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression,
unsafe due to conditions of extreme
Cataplexy syndrome, Anxiety, Insomnia,
neglect. Her foster mother reports that
Neuropathic pain/chronic pain
Caylee is very quiet and withdrawn and
-Full therapeutic benefits may take 2-8 weeks
always appears sad and disinterested in her
-Dosing: in Peds/Adolescents/Adults:
surroundings; however, she becomes very
100-250mg/day
irritable when anything unexpected or
unplanned occurs. The foster mother
became very concerned when it appeared
that Caylee was hallucinating. The PMHNP
considers that:
, Treatment for depression. CNS stimulant
-Known as cyamepromazine Dextroamphetamine Mech: Inc catecholamines at the synaptic cleft, especially NE and dopamine.
-Typical antipsychotic drug of the phenothiazine class. Use: ADHD, narcolepsy, apetite control
-Treatment for schizophrenia
- BBW
and psychosis-associated
> Risk of suicidal ideation; monitor for suicidal thinking or behavior, worsening, or
anxiety
unusual behavior
-Behaves like an atypical
- Contraindications
antipsychotic, due to its
> Glaucoma, pheochromocytoma, MAO I use within past 14 days
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
- Warning
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist,
> Rare, but severe hepatotoxicity (most within 120 days of start of treatment)
Cyamemazine (Tercian) serotonin dopamine antagonist)
Atomoxetine (Strattera) SE
-Commonly Prescribed for (not FDA approved):
> Headache, insomnia, somnolence, dry mouth, nausea, abdominal pain, decrease in
-Schizophrenia
appetite, nausea, etc.
-Anxiety associated with psychosis (short-term)
> Priapism
-Anxiety associated with nonpsychotic disorders, including mood disorders and
NOTE
personality disorders (short-term)
> do not open capsule - irritant
-Severe depression
> CYPD 2D6 substrate
-Bipolar disorder
> watch out for LIVER PROBLEMS
-Other psychotic disorders
-Acute agitation/aggression (injection) Clonidine Hydrochloride Catapres, Catapres TTS, Kapvay (Antihypertensive)
-Benzodiazepine withdrawal
Focalin; Focalin XR Tablet,
Treats depression capsule
Dexmethylphenidate Hydrochloride
Brand: Norpramin CNS Stimulant
-TCA ADHD
-Norepinephrine noradrenaline reuptake inhibitor.
Tenex, Intuniv
-FDA approved for treating depression. Guanfacine Hydrochloride
Antihypertensive/Antipsychotic
-Off-label: Anxiety, Insomnia,
Neuropathic pain/chronic pain, Treatment-resistant depression. Vyvanse
Desiprimine (Norpramine) Lisdexamfetamine
-More potent inhibitor of norepinephrine reuptake pump than serotonin reuptake (ADHD, binge eating disorder)
pump (serotonin transporter).
Methylphenidate Concerta, Ritalin, Metadate, Methylin CNS Agent for ADHD Yes
-May have immediate effects in treating insomnia or anxiety.
-If it is not working within 6-8 weeks for depression, it may require a dosage increase Methylphenidate
or it may not work at all Common brand names: Ritalin, Daytrana
-100-200 mg/day (for depression) methylphenidate hydrocholoride This medication is used to treat attention deficit hyperactivity disorder - ADHD.
50-150 mg/day (for chronic pain). Brand names: Ritalin · Daytrana · Metadate ER · Methylin · Quillivant XR
Drug classes: Central Nervous System Stimulant · CNS Stimulant
Dual serotonin and norepinephrine reuptake inhibitor-often classified as an
antidepressant. =A group of disorders that cause an impaired awareness of your own actions,
Dissociative disorders
-FDA approved to tx MDD. thoughts, physical sensations, and even identity, which is a sense of who you are.
-Off-label: Vasomotor sx's, fibromyalgia, GAD, Social Anx d/o, panic d/o, PTSD, Divided into three main types: depersonalization/derealization disorder, dissociative
Desvenlafaxine (Pristiq) PMDD Dissociative disorders
amnesia, and dissociative identity disorder.
-Dopamine is inactivated by norepinephrine reuptake in frontal cortex (which lack
dopamine transporters) med can increase dopamine neurotransmission in this part of Each of these disorders fall along a spectrum of severity:
the brain -depersonalization/derealization= the least severe of the dissociative disorders,
Dissociative disorders
- -dissociative amnesia= somewhere in the middle of least severe and severe,
-dissociative identity disorder= the most severe.
Atypical Antipsychotic (most "typical" of atypicals)
Side effects: EPS (dose-dependent), TD, significant increases in PRL (check PRL -Might speak in a deadpan manner, with little emotion, and have trouble forming
levels) relationships.
Risperidone (Risperdal) Depersonalization/derealization
--> most dopaminergic of Atypicals -In severe cases, a person may have trouble recognizing familiar places, people, or
objects, and this can make it had to learn tasks.
IM formulation is available Medical food approved by FDA for treatment of (AD)
Caprylidene
drugs that stimulate neural activity, causing speeded-up body functions and Axona
Amphetamines
associated energy and mood changes - Alzheimer's drug
Aducanumab
- decreases amyloid plaques