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UNE BIOCHEM 1005 FINAL EXAM 2025
BRAND NEW ACTUAL EXAM WITH
ANSWERS.
Elevated levels of NADH produced from the oxidation of alcohol
can disrupt the TCA cycle. Which of the following best describes
the interaction of NADH with alpha ketoglutarate dehydrogenase?
a. NADH facilitates a covalent modification
b. NADH is an allosteric activator
c. NADH is an inhibitor
d. NADH inhibits translation of the enzyme - correct answer -c.
NADH is an inhibitor
A 2-year old boy is found to have a pituitary tumor that increases
secretion of ACTH. This will lead to an increase in the secretion of
which of the following hormones?
a. Insulin like growth factor 1 (IGF1)
b. Somatostatin
c. Thyroid hormone
d. Cortisol - correct answer -d. Cortisol
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Which of the following is a direct impact of growth hormone on
metabolic processes?
a. Decrease in skeletal muscle protein synthesis
b. Increase in hepatic gluconeogenesis
c. Decrease in hepatic glycogenolysis
d. Increase in glucose uptake in skeletal muscle - correct answer -
b. Increase in hepatic gluconeogenesis
A 5-year old boy is diagnosed with hyperinsulinemia (elevated
levels of insulin). In this individual, which of the following would be
consistent with this presentation?
a. Hyperlipidemia (increased free fatty acids)
b. Hypoglycemia
c. Hyperglycemia
d. Hyper ketosis (elevated ketone production) - correct answer -b.
Hypoglycemia
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Glucocorticoids such as cortisol stimulate the activity of two
opposing pathways. Which of the two pathways are both
stimulated by elevated levels of cortisol?
a. Lipolysis and β-oxidation
b. Glycogen synthesis and gluconeogenesis
c. Protein catabolism and skeletal muscle protein synthesis
d. Glycolysis and gluconeogenesis - correct answer -b. Glycogen
synthesis and gluconeogenesis
There are several key regulatory enzymes in gluconeogenesis.
Which of the following answers below lists these enzymes in the
correct order in which they are used for glucose production?
a. Pyruvate carboxylase; phosphoenol pyruvate carboxykinase
(PEPCK); Fructose 1,6 bisphosphatase
b. Pyruvate carboxylase; phosphoenol pyruvate carboxykinase
(PEPCK); phosphofructokinase 2 (PFK2)
c. Pyruvate carboxylase; PEPCK; hexokinase
d. Pyruvate kinase; pyruvate dehydrogenase;
phosphofructokinase 1 (PFK1) - correct answer -a. Pyruvate
carboxylase; phosphoenol pyruvate carboxykinase (PEPCK);
Fructose 1,6 bisphosphatase
UNE BIOCHEM 1005 FINAL EXAM 2025
BRAND NEW ACTUAL EXAM WITH
ANSWERS.
Elevated levels of NADH produced from the oxidation of alcohol
can disrupt the TCA cycle. Which of the following best describes
the interaction of NADH with alpha ketoglutarate dehydrogenase?
a. NADH facilitates a covalent modification
b. NADH is an allosteric activator
c. NADH is an inhibitor
d. NADH inhibits translation of the enzyme - correct answer -c.
NADH is an inhibitor
A 2-year old boy is found to have a pituitary tumor that increases
secretion of ACTH. This will lead to an increase in the secretion of
which of the following hormones?
a. Insulin like growth factor 1 (IGF1)
b. Somatostatin
c. Thyroid hormone
d. Cortisol - correct answer -d. Cortisol
, Page | 2
Which of the following is a direct impact of growth hormone on
metabolic processes?
a. Decrease in skeletal muscle protein synthesis
b. Increase in hepatic gluconeogenesis
c. Decrease in hepatic glycogenolysis
d. Increase in glucose uptake in skeletal muscle - correct answer -
b. Increase in hepatic gluconeogenesis
A 5-year old boy is diagnosed with hyperinsulinemia (elevated
levels of insulin). In this individual, which of the following would be
consistent with this presentation?
a. Hyperlipidemia (increased free fatty acids)
b. Hypoglycemia
c. Hyperglycemia
d. Hyper ketosis (elevated ketone production) - correct answer -b.
Hypoglycemia
, Page | 3
Glucocorticoids such as cortisol stimulate the activity of two
opposing pathways. Which of the two pathways are both
stimulated by elevated levels of cortisol?
a. Lipolysis and β-oxidation
b. Glycogen synthesis and gluconeogenesis
c. Protein catabolism and skeletal muscle protein synthesis
d. Glycolysis and gluconeogenesis - correct answer -b. Glycogen
synthesis and gluconeogenesis
There are several key regulatory enzymes in gluconeogenesis.
Which of the following answers below lists these enzymes in the
correct order in which they are used for glucose production?
a. Pyruvate carboxylase; phosphoenol pyruvate carboxykinase
(PEPCK); Fructose 1,6 bisphosphatase
b. Pyruvate carboxylase; phosphoenol pyruvate carboxykinase
(PEPCK); phosphofructokinase 2 (PFK2)
c. Pyruvate carboxylase; PEPCK; hexokinase
d. Pyruvate kinase; pyruvate dehydrogenase;
phosphofructokinase 1 (PFK1) - correct answer -a. Pyruvate
carboxylase; phosphoenol pyruvate carboxykinase (PEPCK);
Fructose 1,6 bisphosphatase
