Verified 100% Correct
All supply outlets served by a common air handler should be measured
____ _____ to minimize system variation. - ANSWER without interruption
____ _____ should be used when measuring airflow volume with hoods as
recommended by the device manufacture. - ANSWER Backpressure
compensation
Unidirectional zones (ISO 5 LAFW hood) utilize _____ control instead of
dilution control and are measured in velocity (Vel grid). - ANSWER flow
Velocity is measured using a ______ _______ or electronic manometer
with multipoint tube array sensor - ANSWER thermal anemometer
Grid measurements. ___" from edges, ____" from filter diffuser screen -
ANSWER 6 6
Unless specified by device manufacturer, average velocity should be
between ___ and ___ FPM. - ANSWER 80 - 110
Alternative velocity ranges can be assigned if airflow visualization indicate
smooth airflow with no ____ or ___ _____ ____ within the DCA (Direct
Compounding Area) and air is drawn away from the critical site to the return
or out of the PEC (Primary Engineering Control). - ANSWER Refluxing
dead air spots.
Rooms used to compound sterile preparations need to be isolated from
surrounding spaces typically through pressurization but also ____
displacement. - ANSWER Airflow
Non-hazardous compounding must have a minimum positive pressure
differential of ______"w.c. relative to adjacent spaces. - ANSWER 0.020
, Hazardous must have a minimum of _____" w.c. negative relative to
adjacent spaces. - ANSWER 0.010
For cart pass-throughs, if the area is used as a cleaning or material prep
space, there should be a _____"w.c. cascade of cleanest room to the pass
through - ANSWER 0.020
To test displacement airflow velocity, divide the opening between two
adjacent space into a grid of equal areas not exceeding ___ ft2 starting 6"
from all edges unless not possible. Take a velocity reading at each grid
location which should be greater than ___ fpm. - ANSWER 4 60
To create airflow visualization, generate neutrally buoyant airflow medium
across the entire area being tested with a separate pass being made along
the entire perimeter and across the entire opening. Verify _____ and
provide video documentation. - ANSWER no reverse flow
A challenge of __ - ___ microgram per liter should be used. - ANSWER
10 90
Leaks should not exceed ______% of the upstream challenge. -
ANSWER 0.010
Scans should be done at a rate of ____"/second. - ANSWER 2
When testing, disable ____ if present. - ANSWER smoke detectors
Classification of cleanliness levels is done with a ____ ____ survey. -
ANSWER particle count
Per USP 797, ISO 7 class _____ or cleaner - ANSWER 10,000
Per USP 797, ISO 8 class _____ or cleaner. - ANSWER 100,000
Ante areas adjacent to a negative pressure buffer area should meet ____
class - ANSWER ISO 7
, A calibrated particle counter must be used that can detect particles of ____
microns. - ANSWER 0.5
A calibrated particle counter should use a ___ in conjunction to verify
performance. - ANSWER zero-filter
The volume sampled at each location shall be at least ____ with a
minimum sampling time of ____ - ANSWER 2 liters 1 minute.
Divide the test zone into grids of equal area. The minimum number of
sample locations shall be no less than the _______ of the clean space area
in square meters. Sampling should be taken in the direction of the airflow or
pointing upward if non-unidirectional. - ANSWER square root
USP 797 does not require a range for temperature or humidity but does
recommend temperatures below _____ and humidity of ____. - ANSWER
68 F/ 20 C and 35% to 60%
BSCs are tested at ___ international and can only be certified by ____
certification professionals. - ANSWER NSF; NSF
In addition to the NSF certification process, the BSC must be certified to
meet ISO __. - ANSWER 5
True/False: When compounding non-hazardous drugs, USP does not
specify conditions for the room isolators are in. - ANSWER True
For hazardous drugs, the room with an isolator should be certified to at
least ___ ACPH and at least ____" w.c. negative to adjacent rooms and
spaces. - ANSWER 12; 0.01
Average airflow velocities are typically set to a range of _____ fpm unless
otherwise decided. - ANSWER 80 to 100
Hood air flow readings should be taken in a plane ___ inches from the filter
face. - ANSWER 6-12