NU 214-1 Pharmacokinetics Mason Questions with
Detailed Verified Answers for Accuracy
What is Pharmacokinetics?
✓✓ The study of drug movement throughout the body
What does 'pharmakon' mean?
✓✓ Medicine (drug) or poison
What does 'kinesis' mean?
✓✓ Motion
Pharmacokinetics is the motion of the medicine/drug ie. what
the (body/drug) does to the (body/drug).
✓✓ What the *body* does to the *drug*
What are 4 stages of Pharmacokinetics?
✓✓ 1. Absorption
2. Distribution
3. Metabolism
4. Excretion
*Absorption*
✓✓
Absorption is when...
, ACCURACY IS GUARANTEED
✓✓ The drug enters the blood stream
Bioavailability describes what?
✓✓ The degree to which the drug is absorbed and transported
to the blood
The percent of a drug that is available to produce the effect
Note:
✓✓ Bioavailability is important because a drug that is absorbed
in the intestine must pass through the liver before it reaches
systemic circulation. Therefore when the liver filters it, it's
important there is still enough of a percentage left to produce
the desired affect
*the more that is broken down, the less we have to use
What is a bioequivalent?
✓✓ 2 drugs with the same bioavailability
The initial metabolism in the liver of the drug is called?
✓✓ The hepatic First Pass Effect
Drug with a *high* first pass effect are given by routes other
than...
✓✓ Oral