Ultimate NCLEX-RN Comprehensive Study Guide 2025 Practice
Questions & Rationales
Stuvia 5-Star Gold
May 2025
2025 NCLEX-RN A+ Comprehensive Q&A for Exam Success
This ultimate NCLEX-RN study guide ensures success in the 2025 exam, covering Safe and Effective Care, Health
Promotion, Psychosocial Integrity, and Physiological Integrity. It includes 30 high-yield questions: 20 multiple-
choice (1 mark each, 20 marks), 5 select-all-that-apply (2 marks each, 10 marks), and 5 case-study-based (2 marks
each, 10 marks). Total: 40 marks. Verified answers, rationales, and secret hints and helpers deliver Stuvia 5-star
quality. Aligns with NCSBNs 2025 test plan and Next Generation NCLEX (NGN) formats.
Section A: Multiple-Choice Questions (20 marks)
Answer all questions. Select the best answer. No negative marking.
1. A nurse administers insulin to a diabetic patient. Which action ensures safety?
A) Using a 1-mL syringe B) Verifying the dose with another nurse C) Injecting without site rotation
D) Administering without checking glucose
Secret Hint and Helper: Focus on Joint Commission safety protocols.
Correct Answer: B. Verifying the dose with another nurse.
Rationale: Insulin is a high-alert medication. Verification with another nurse reduces errors, per ISMP
guidelines. A) Incorrect syringe size risks dosing errors. C) Site rotation prevents lipodystrophy. D) Glucose
checks are mandatory.
2. A patient with MRSA is on contact precautions. Which PPE is essential?
A) N95 mask B) Gloves and gown C) Face shield D) Shoe covers
Secret Hint and Helper: Recall CDC infection control guidelines.
Correct Answer: B. Gloves and gown.
Rationale: MRSA requires contact precautions (gloves, gown), per CDC. A) N95 is for airborne pathogens.
C) Face shield is for droplet precautions. D) Shoe covers are not required.
3. A patient reports chest pain. Which assessment is priority?
A) Blood pressure B) Pain scale C) Respiratory rate D) Oxygen saturation
Secret Hint and Helper: Use ABC prioritization.
Correct Answer: D. Oxygen saturation.
Rationale: Chest pain may indicate hypoxia; oxygen saturation assesses airway and breathing, per ABCs.
A) BP is secondary. B) Pain scale follows ABCs. C) Respiratory rate is less urgent than SpO2.
4. A nurse teaches a patient about warfarin. Which food should be limited?
A) Apples B) Spinach C) Chicken D) Rice
Secret Hint and Helper: Recall vitamin Ks role in clotting.
Correct Answer: B. Spinach.
Rationale: Spinach is high in vitamin K, which antagonizes warfarins anticoagulant effect. A, C, D) These
foods have minimal vitamin K.
5. A patient with depression refuses medication. What is the nurses best response?
A) Insist on compliance B) Explore reasons for refusal C) Notify the provider immediately D) Docu-
ment refusal only
Secret Hint and Helper: Focus on therapeutic communication.
Correct Answer: B. Explore reasons for refusal.
Rationale: Exploring reasons respects autonomy and builds trust, per ANA standards. A) Insisting violates
autonomy. C) Notification is premature. D) Documentation is needed but not sufficient alone.
6. A patient with a new colostomy asks about diet. What should the nurse recommend?
A) High-fiber foods B) Low-residue diet C) Spicy foods D) Carbonated drinks
Secret Hint and Helper: Consider stoma output management.
Correct Answer: B. Low-residue diet.
1
Questions & Rationales
Stuvia 5-Star Gold
May 2025
2025 NCLEX-RN A+ Comprehensive Q&A for Exam Success
This ultimate NCLEX-RN study guide ensures success in the 2025 exam, covering Safe and Effective Care, Health
Promotion, Psychosocial Integrity, and Physiological Integrity. It includes 30 high-yield questions: 20 multiple-
choice (1 mark each, 20 marks), 5 select-all-that-apply (2 marks each, 10 marks), and 5 case-study-based (2 marks
each, 10 marks). Total: 40 marks. Verified answers, rationales, and secret hints and helpers deliver Stuvia 5-star
quality. Aligns with NCSBNs 2025 test plan and Next Generation NCLEX (NGN) formats.
Section A: Multiple-Choice Questions (20 marks)
Answer all questions. Select the best answer. No negative marking.
1. A nurse administers insulin to a diabetic patient. Which action ensures safety?
A) Using a 1-mL syringe B) Verifying the dose with another nurse C) Injecting without site rotation
D) Administering without checking glucose
Secret Hint and Helper: Focus on Joint Commission safety protocols.
Correct Answer: B. Verifying the dose with another nurse.
Rationale: Insulin is a high-alert medication. Verification with another nurse reduces errors, per ISMP
guidelines. A) Incorrect syringe size risks dosing errors. C) Site rotation prevents lipodystrophy. D) Glucose
checks are mandatory.
2. A patient with MRSA is on contact precautions. Which PPE is essential?
A) N95 mask B) Gloves and gown C) Face shield D) Shoe covers
Secret Hint and Helper: Recall CDC infection control guidelines.
Correct Answer: B. Gloves and gown.
Rationale: MRSA requires contact precautions (gloves, gown), per CDC. A) N95 is for airborne pathogens.
C) Face shield is for droplet precautions. D) Shoe covers are not required.
3. A patient reports chest pain. Which assessment is priority?
A) Blood pressure B) Pain scale C) Respiratory rate D) Oxygen saturation
Secret Hint and Helper: Use ABC prioritization.
Correct Answer: D. Oxygen saturation.
Rationale: Chest pain may indicate hypoxia; oxygen saturation assesses airway and breathing, per ABCs.
A) BP is secondary. B) Pain scale follows ABCs. C) Respiratory rate is less urgent than SpO2.
4. A nurse teaches a patient about warfarin. Which food should be limited?
A) Apples B) Spinach C) Chicken D) Rice
Secret Hint and Helper: Recall vitamin Ks role in clotting.
Correct Answer: B. Spinach.
Rationale: Spinach is high in vitamin K, which antagonizes warfarins anticoagulant effect. A, C, D) These
foods have minimal vitamin K.
5. A patient with depression refuses medication. What is the nurses best response?
A) Insist on compliance B) Explore reasons for refusal C) Notify the provider immediately D) Docu-
ment refusal only
Secret Hint and Helper: Focus on therapeutic communication.
Correct Answer: B. Explore reasons for refusal.
Rationale: Exploring reasons respects autonomy and builds trust, per ANA standards. A) Insisting violates
autonomy. C) Notification is premature. D) Documentation is needed but not sufficient alone.
6. A patient with a new colostomy asks about diet. What should the nurse recommend?
A) High-fiber foods B) Low-residue diet C) Spicy foods D) Carbonated drinks
Secret Hint and Helper: Consider stoma output management.
Correct Answer: B. Low-residue diet.
1
