MARYVILLE NURS 615 EXAM 1
EXAM WITH CORRECT QUESTIONS
AND ANSWERS 2025
• NP prescriptive authority is regulated by - CORRECT-ANSWERSthe state board of
nursing
• Criteria for choosing an effective drug for a disorder - CORRECT-ANSWERSConsulting
nationally recognized guidelines for disease management
• Hypoalbuminemia affects the process of prescribing because - CORRECT-ANSWERSit
increases the free drug floating around and could cause toxicity or different effects
• Hypoalbuminemia - CORRECT-ANSWERSaffects the distribution of the drug to target
tissue
• Drugs with high first pass metabolism - CORRECT-ANSWERSare rapidly metabolized
by the liver and may have little or if any desired action.
• Fraction of drug lost through the process of absorption.
• First pass metabolism - CORRECT-ANSWERSThe rapid uptake and metabolism of an
active compound into inactive compounds by the liver, immediately after enteric
absorption and before it reaches the systemic circulation.
• Half-life - CORRECT-ANSWERSthe amount of time it takes for an administered drug to
be half-way cleared from the system
• Loading dose - CORRECT-ANSWERSdrugs with a long half life start with this to
achieve desired clinical effects more quickly.
• Ex: azithromycin requires the first days dose to be twice that of the other 4 days
, • Onset of action - CORRECT-ANSWERSThe point in time on the drug concentration
curve that indicates the first sign of a therapeutic effect
• Peak of action - CORRECT-ANSWERSThe time between drug administration and the
maximum concentration of a drug in the blood stream
• Peak and trough levels - CORRECT-ANSWERSThis is used to determine if a drug is in a
therapeutic range
• Steady-state - CORRECT-ANSWERSAmount of drug needed in the body remains
constant
• IV administration - CORRECT-ANSWERSDoes not involve absorption and there is no
loss of the drug; distribution throughout the body begins immediately
• CYPs - CORRECT-ANSWERSare major enzymes that are involved in drug metabolism.
They account for nearly 75% of the total metabolism.
• Drugs that utilize the CYP3A4 isoenzymes for metabolism - CORRECT-ANSWERSmay
induce the metabolism of another drug or inhibit the metabolism of another drug
• CYP450 - CORRECT-ANSWERSis the reason behind drug interaction and the rationale
of why drugs affect different people in different ways
• Grapefruit - CORRECT-ANSWERSreduces the clearance of simvastatin, increasing the
risk of myopathy
• St. John's Wort - CORRECT-ANSWERSreduces the clearance of cyclosporine
• Bactrim and Warfarin - CORRECT-ANSWERSwarfarin metabolism is reduced, resulting
in increased INR causing an increased risk of bleeding and should be avoided or the INR
should be monitored more frequently
EXAM WITH CORRECT QUESTIONS
AND ANSWERS 2025
• NP prescriptive authority is regulated by - CORRECT-ANSWERSthe state board of
nursing
• Criteria for choosing an effective drug for a disorder - CORRECT-ANSWERSConsulting
nationally recognized guidelines for disease management
• Hypoalbuminemia affects the process of prescribing because - CORRECT-ANSWERSit
increases the free drug floating around and could cause toxicity or different effects
• Hypoalbuminemia - CORRECT-ANSWERSaffects the distribution of the drug to target
tissue
• Drugs with high first pass metabolism - CORRECT-ANSWERSare rapidly metabolized
by the liver and may have little or if any desired action.
• Fraction of drug lost through the process of absorption.
• First pass metabolism - CORRECT-ANSWERSThe rapid uptake and metabolism of an
active compound into inactive compounds by the liver, immediately after enteric
absorption and before it reaches the systemic circulation.
• Half-life - CORRECT-ANSWERSthe amount of time it takes for an administered drug to
be half-way cleared from the system
• Loading dose - CORRECT-ANSWERSdrugs with a long half life start with this to
achieve desired clinical effects more quickly.
• Ex: azithromycin requires the first days dose to be twice that of the other 4 days
, • Onset of action - CORRECT-ANSWERSThe point in time on the drug concentration
curve that indicates the first sign of a therapeutic effect
• Peak of action - CORRECT-ANSWERSThe time between drug administration and the
maximum concentration of a drug in the blood stream
• Peak and trough levels - CORRECT-ANSWERSThis is used to determine if a drug is in a
therapeutic range
• Steady-state - CORRECT-ANSWERSAmount of drug needed in the body remains
constant
• IV administration - CORRECT-ANSWERSDoes not involve absorption and there is no
loss of the drug; distribution throughout the body begins immediately
• CYPs - CORRECT-ANSWERSare major enzymes that are involved in drug metabolism.
They account for nearly 75% of the total metabolism.
• Drugs that utilize the CYP3A4 isoenzymes for metabolism - CORRECT-ANSWERSmay
induce the metabolism of another drug or inhibit the metabolism of another drug
• CYP450 - CORRECT-ANSWERSis the reason behind drug interaction and the rationale
of why drugs affect different people in different ways
• Grapefruit - CORRECT-ANSWERSreduces the clearance of simvastatin, increasing the
risk of myopathy
• St. John's Wort - CORRECT-ANSWERSreduces the clearance of cyclosporine
• Bactrim and Warfarin - CORRECT-ANSWERSwarfarin metabolism is reduced, resulting
in increased INR causing an increased risk of bleeding and should be avoided or the INR
should be monitored more frequently
