NAPLEX Clinical Pharmacology: 20 High-Yield MCQs with Clear Rationales
1. 1. A 65-year-old male with a history of heart failure is prescribed furosemide. Which of the
following should be monitored regularly?
A. Liver enzymes
B. Potassium levels
C. Hemoglobin A1c
D. INR
Correct Answer: B. Potassium levels
Rationale: Furosemide is a loop diuretic that can cause significant potassium loss. Regular
monitoring is important to prevent hypokalemia.
2. 2. Which of the following insulin types is considered long-acting?
A. Insulin lispro
B. Insulin aspart
C. Insulin glargine
D. Regular insulin
Correct Answer: C. Insulin glargine
Rationale: Insulin glargine is a long-acting insulin used for basal glucose control and typically
administered once daily.
3. 3. A patient is prescribed lisinopril. Which adverse effect should the pharmacist counsel the
patient about?
A. Constipation
B. Dry cough
C. Hypoglycemia
D. Insomnia
Correct Answer: B. Dry cough
Rationale: ACE inhibitors like lisinopril commonly cause a dry cough due to accumulation of
bradykinin.
1. 1. A 65-year-old male with a history of heart failure is prescribed furosemide. Which of the
following should be monitored regularly?
A. Liver enzymes
B. Potassium levels
C. Hemoglobin A1c
D. INR
Correct Answer: B. Potassium levels
Rationale: Furosemide is a loop diuretic that can cause significant potassium loss. Regular
monitoring is important to prevent hypokalemia.
2. 2. Which of the following insulin types is considered long-acting?
A. Insulin lispro
B. Insulin aspart
C. Insulin glargine
D. Regular insulin
Correct Answer: C. Insulin glargine
Rationale: Insulin glargine is a long-acting insulin used for basal glucose control and typically
administered once daily.
3. 3. A patient is prescribed lisinopril. Which adverse effect should the pharmacist counsel the
patient about?
A. Constipation
B. Dry cough
C. Hypoglycemia
D. Insomnia
Correct Answer: B. Dry cough
Rationale: ACE inhibitors like lisinopril commonly cause a dry cough due to accumulation of
bradykinin.
