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Samenvatting Hoofdstuk 7&8 : Niet-vergistende strikt aerobe gramnegatieve staven & Moeilijk kweekbare gramnegatieve bacteriën (HACEK-groep)

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Samenvatting Microbiologie 2 (2VD fase 1) Voeding-en dieetkunde Thomas more te Geel

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H7 & 8



Hoofdstuk 7 : Niet-vergistende strikt aerobe
gramnegatieve staven

Algemeen niet vergisters
 Strikt aerobe Gramnegatieve bacillen
 Heterogene groep saprofieten.
 Leven vrij in de natuur
 Worden regelmatig afgezonderd bij de mens
 Algemene eigenschappen
 Goede groei op McConkey
 Geen vergisting van suikers op Kligler
 Meestal oxidase positief en beweeglijk


Pseudomonas
 Zeer verspreid als saprofieten in de natuur
 Onderdeel van de transiënte flora bij de mens
 Typische hospitaalpathogeen
 Virulent voor
 Patiënten met sterk verminderde weerstand
o Ziekten zoals kanker, leukemie, mucoviscidose,
immuundeficiënties…
o Behandeling met cytostatica, immunodepressiva, corticosteroïden…
o Lokale factoren zoals brandwonden, doorligwonden, tracheotomie,
puncties…

Voornaamste infecties
Overal in het lichaam
 Wondinfecties na brandwonde, decubitus (doorligwonden)..
 Luchtweginfecties
 Urologische infecties
 Endocarditis
 Folliculitis en otitis externa of media
 Sepsis bij zware immuundeficiëntie
 Meningitis na neurochirurgie of niet steriel uitgevoerde lumbaalpunctie

Virulentiefactoren
 Adhesines
 Pili
 Polysacharide kapsel
 Alginaatslijm (biofilm)
 Invasines
 Elastase
 Alkalisch protease
 Hemolysines (fosfolipase en lecithinase)
 Cytotoxine

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Uploaded on
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Number of pages
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Written in
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