MedConnoisseur Files:
@lo @lo
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration @loof @looxytocin @lohas @lobeen @loproposed @loas @loa @lotreatment @lofor
@loautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
6. Which @lofactor @lodoes @lonot @loaffect @lothe @lopharmacokinetics @loof @loa @lodrug?
a. Route @loof @loadministration
b. Lipid @losolubility
c. Depot @lobinding
d. Drug @loaction
Answer: @lod
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
7. First-pass @lometabolism @looccurs @lowhen @lodrugs @loare @lotaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
8. The @loarea @lopostrema @lois @loone @loarea @loin @lothe @lobrain @lowhere @lothe is @lonot @locomplete.
a. cerebrospinal @lofluid
b. blood–brain @lobarrier
c. choroid @loplexus
d. phospholipid @lomembrane
Answer: @lob
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
9. First-pass @lometabolism @looccurs @lowith @loorally @loadministered @lodrugs @lobecause
a. their @loabsorption @lois @loslowed @loby @lofood.
b. drugs @loabsorbed @lointo @lothe @lobloodstream @lofrom @lothe @lostomach @logo @loto @lothe @loliver
@loon @lothe @loway @loto @logeneral @locirculation.
c. drugs @lomust @lofirst @losurvive @lothe @loacidic @loenvironment @loof @lothe @lostomach.
d. salivary @loenzymes @loin @lothe @lomouth @lobegin @lothe @loprocess @loof @lometabolism.
Answer: @lob
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
10. Toxic @losubstances @loin @lothe @loblood @lotrigger @loa @lovomiting @loresponse @loby @loactivating @lothe
a. blood–brain @lobarrier.
b. choroid @loplexus.
c. area @lopostrema.
d. median @loeminence.
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, Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
11. Drugs @loadministered @lo_ have @lothe @lomost @lorapid @loonset @loof @loaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: @lod
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
12. Ionization @loof @loa @lodrug @lodepends @loon @lothe of @lothe @losolution @loand @lothe of
@lothe @lodrug.
a. pH; @lopKa
b. pKa; @lopH
c. concentration; @lolipid @losolubility
d. pH; @loconcentration
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
13. The @loabsorption @loof @loa @lodrug @lodepends @loon @loall @loof @lothe @lofollowing @loexcept
a. lipid @losolubility.
b. ionization.
c. body @lotemperature.
d. the @loconcentration @loof @lothe @lodrug.
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
14. Drugs @lothat @loare should @lobe @loavoided @loby @lowomen @loof @lochildbearing @loage.
a. teratogenic
b. able @loto @locross @lothe @loplacental @lobarrier
c. psychoactive
d. highly @lolipid-soluble
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
15. Agents @lothat @loinduce @lodevelopmental @loabnormalities @loin @loa @lofetus @loare @loknown @loas
a. psychoactive @lodrugs.
b. illicit @lodrugs.
c. teratogens.
d. placental @lodrugs.
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
16. Depot @lobinding @lois @losaid @loto @looccur @lowhen @lodrugs
a. bind @loto @lotheir @lotarget @losites.
WWW.THENURSINGMASTERY.COM
Page @lo3 @loof
@lo247
@lo @lo
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
WWW.THENURSINGMASTERY.COM
Page @lo1 @loof
@lo247
,5. The administration @loof @looxytocin @lohas @lobeen @loproposed @loas @loa @lotreatment @lofor
@loautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
6. Which @lofactor @lodoes @lonot @loaffect @lothe @lopharmacokinetics @loof @loa @lodrug?
a. Route @loof @loadministration
b. Lipid @losolubility
c. Depot @lobinding
d. Drug @loaction
Answer: @lod
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
7. First-pass @lometabolism @looccurs @lowhen @lodrugs @loare @lotaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
8. The @loarea @lopostrema @lois @loone @loarea @loin @lothe @lobrain @lowhere @lothe is @lonot @locomplete.
a. cerebrospinal @lofluid
b. blood–brain @lobarrier
c. choroid @loplexus
d. phospholipid @lomembrane
Answer: @lob
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
9. First-pass @lometabolism @looccurs @lowith @loorally @loadministered @lodrugs @lobecause
a. their @loabsorption @lois @loslowed @loby @lofood.
b. drugs @loabsorbed @lointo @lothe @lobloodstream @lofrom @lothe @lostomach @logo @loto @lothe @loliver
@loon @lothe @loway @loto @logeneral @locirculation.
c. drugs @lomust @lofirst @losurvive @lothe @loacidic @loenvironment @loof @lothe @lostomach.
d. salivary @loenzymes @loin @lothe @lomouth @lobegin @lothe @loprocess @loof @lometabolism.
Answer: @lob
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
10. Toxic @losubstances @loin @lothe @loblood @lotrigger @loa @lovomiting @loresponse @loby @loactivating @lothe
a. blood–brain @lobarrier.
b. choroid @loplexus.
c. area @lopostrema.
d. median @loeminence.
WWW.THENURSINGMASTERY.COM
Page @lo2 @loof
@lo247
, Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
11. Drugs @loadministered @lo_ have @lothe @lomost @lorapid @loonset @loof @loaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: @lod
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
12. Ionization @loof @loa @lodrug @lodepends @loon @lothe of @lothe @losolution @loand @lothe of
@lothe @lodrug.
a. pH; @lopKa
b. pKa; @lopH
c. concentration; @lolipid @losolubility
d. pH; @loconcentration
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
13. The @loabsorption @loof @loa @lodrug @lodepends @loon @loall @loof @lothe @lofollowing @loexcept
a. lipid @losolubility.
b. ionization.
c. body @lotemperature.
d. the @loconcentration @loof @lothe @lodrug.
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
14. Drugs @lothat @loare should @lobe @loavoided @loby @lowomen @loof @lochildbearing @loage.
a. teratogenic
b. able @loto @locross @lothe @loplacental @lobarrier
c. psychoactive
d. highly @lolipid-soluble
Answer: @loa
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
15. Agents @lothat @loinduce @lodevelopmental @loabnormalities @loin @loa @lofetus @loare @loknown @loas
a. psychoactive @lodrugs.
b. illicit @lodrugs.
c. teratogens.
d. placental @lodrugs.
Answer: @loc
Textbook @loReference: @loPharmacokinetic @loFactors @loDetermining @loDrug @loAction
16. Depot @lobinding @lois @losaid @loto @looccur @lowhen @lodrugs
a. bind @loto @lotheir @lotarget @losites.
WWW.THENURSINGMASTERY.COM
Page @lo3 @loof
@lo247