Week 9 Clinical Study
Suze Pierre
Canvas
HSC3310_ONL2FA_ONL2F_25 - Cross-Sectional Anatomy
Jessica Williams
4/18/2025
This study source was downloaded by 100000898495062 from CourseHero.com on 05-13-2025 03:02:24 GMT -05:00
https://www.coursehero.com/file/248858188/Week-9-Clinical-Studydocx/
, Question One:
The late stages of untreated syphilis infection result in a neurological condition known as Tabes
dorsalis. The degenerative process of tabes dorsalis targets the dorsal (posterior) columns and the
dorsal roots within the spinal cord. The spinal nerve depends on its dorsal root as a vital component
that connects peripheral sensory information from skin and muscle to the central nervous system.
The syphilitic infection in tabes dorsalis demolishes sensory neurons through demyelination and
destruction, which causes patients to lose their ability to detect deep pain sensations and vibration
senses, along with proprioception (Kumar & Zito, 2023).
Sensory information transmission through the dorsal root becomes impaired by its degenerative
state, which causes ataxia, lightning pains, and a positive Romberg sign. The inability to transmit
sensory information causes patients to develop decreased reflexes and worsening locomotor ataxia
because their bodies lack the necessary movement coordination signals (Findling et al., 2021).
Question Two:
Multiple sclerosis (MS) is an autoimmune disease that produces persistent inflammation and
demyelination of central nervous system tissue (Platero et al., 2021). Neurons receive electrical
impulses at fast speeds because the myelin sheath forms an insulating layer that covers their
surface. The immune system in MS attacks the myelin by mistake, causing lesions and scarring,
known as sclerosis, to develop in the CNS (Reich et al., 2018).
The destruction of myelin sheaths either slows nerve signal transmission or creates complete
electrical blockages that generate neurological symptoms based on the impacted neurological area.
The symptoms of myelin sheath damage include visual problems, muscle weakness, spastic
movements, numbness and fatigue and coordination difficulties. The progressive disability in
This study source was downloaded by 100000898495062 from CourseHero.com on 05-13-2025 03:02:24 GMT -05:00
https://www.coursehero.com/file/248858188/Week-9-Clinical-Studydocx/
Suze Pierre
Canvas
HSC3310_ONL2FA_ONL2F_25 - Cross-Sectional Anatomy
Jessica Williams
4/18/2025
This study source was downloaded by 100000898495062 from CourseHero.com on 05-13-2025 03:02:24 GMT -05:00
https://www.coursehero.com/file/248858188/Week-9-Clinical-Studydocx/
, Question One:
The late stages of untreated syphilis infection result in a neurological condition known as Tabes
dorsalis. The degenerative process of tabes dorsalis targets the dorsal (posterior) columns and the
dorsal roots within the spinal cord. The spinal nerve depends on its dorsal root as a vital component
that connects peripheral sensory information from skin and muscle to the central nervous system.
The syphilitic infection in tabes dorsalis demolishes sensory neurons through demyelination and
destruction, which causes patients to lose their ability to detect deep pain sensations and vibration
senses, along with proprioception (Kumar & Zito, 2023).
Sensory information transmission through the dorsal root becomes impaired by its degenerative
state, which causes ataxia, lightning pains, and a positive Romberg sign. The inability to transmit
sensory information causes patients to develop decreased reflexes and worsening locomotor ataxia
because their bodies lack the necessary movement coordination signals (Findling et al., 2021).
Question Two:
Multiple sclerosis (MS) is an autoimmune disease that produces persistent inflammation and
demyelination of central nervous system tissue (Platero et al., 2021). Neurons receive electrical
impulses at fast speeds because the myelin sheath forms an insulating layer that covers their
surface. The immune system in MS attacks the myelin by mistake, causing lesions and scarring,
known as sclerosis, to develop in the CNS (Reich et al., 2018).
The destruction of myelin sheaths either slows nerve signal transmission or creates complete
electrical blockages that generate neurological symptoms based on the impacted neurological area.
The symptoms of myelin sheath damage include visual problems, muscle weakness, spastic
movements, numbness and fatigue and coordination difficulties. The progressive disability in
This study source was downloaded by 100000898495062 from CourseHero.com on 05-13-2025 03:02:24 GMT -05:00
https://www.coursehero.com/file/248858188/Week-9-Clinical-Studydocx/
