NR547 Week 5 Quiz Bundle 2025 | Real Exam
Questions and Verified A+ Answers
Medications for depression - SSRIs
SNRIs
SDRIs
TCAs
MAOIs
SSRIs - -Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
• agitation
• diarrhea
• headache
• weight gain
• sexual side effects
SNRIs - -inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
• sweating
• tremors
, • anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
SDRIs - -inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
• headache
• dry mouth
• constipation
• weight loss
TCAs - -Action: inhibits the reuptake of serotonin and norepinephrine; blocks
norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
• blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
, MAOIs - -Action: increases norepinephrine and serotonin by inhibiting the
enzyme that inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) - mild antihistamine effects
Prescribing pearls: escitalopram (Lexapro) - no known drug interactions
Prescribing pearls: fluoxetine (Prozac) - longest half-life
Prescribing pearls: paroxetine (Paxil) - also treats social anxiety and insomnia
Prescribing pearls: fluvoxamine (Luvox) - treats anxious depression smokers
require increased dose
Prescribing pearls: sertraline (Zoloft) - also treats social anxiety and
hypersomnolence
Prescribing pearls: bupropion (Wellbutrin) - NDRI may improve energy, alertness,
and motivation; not first line treatment for anxiety; contraindicated in clients with a history of
seizures
Prescribing pearls: duloxetine (Cymbalta) - effective for atypical pain at higher
doses; appropriate for clients who present with somatic symptoms of depression; effective for
atypical pain, such as fibromyalgia and diabetic neuropathy
Prescribing pearls: venlafaxine (Effexor) - treats both depression and anxiety
disorders, ensure trial of higher dose before switching to a different medication
Prescribing pearls: desvenlafaxine (Pristiq) - effective for perimenopausal
vasomotor symptoms
considered when selecting a medication: - -Client preference
-Prior treatment response
Questions and Verified A+ Answers
Medications for depression - SSRIs
SNRIs
SDRIs
TCAs
MAOIs
SSRIs - -Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
• agitation
• diarrhea
• headache
• weight gain
• sexual side effects
SNRIs - -inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
• sweating
• tremors
, • anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
SDRIs - -inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
• headache
• dry mouth
• constipation
• weight loss
TCAs - -Action: inhibits the reuptake of serotonin and norepinephrine; blocks
norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
• blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
, MAOIs - -Action: increases norepinephrine and serotonin by inhibiting the
enzyme that inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) - mild antihistamine effects
Prescribing pearls: escitalopram (Lexapro) - no known drug interactions
Prescribing pearls: fluoxetine (Prozac) - longest half-life
Prescribing pearls: paroxetine (Paxil) - also treats social anxiety and insomnia
Prescribing pearls: fluvoxamine (Luvox) - treats anxious depression smokers
require increased dose
Prescribing pearls: sertraline (Zoloft) - also treats social anxiety and
hypersomnolence
Prescribing pearls: bupropion (Wellbutrin) - NDRI may improve energy, alertness,
and motivation; not first line treatment for anxiety; contraindicated in clients with a history of
seizures
Prescribing pearls: duloxetine (Cymbalta) - effective for atypical pain at higher
doses; appropriate for clients who present with somatic symptoms of depression; effective for
atypical pain, such as fibromyalgia and diabetic neuropathy
Prescribing pearls: venlafaxine (Effexor) - treats both depression and anxiety
disorders, ensure trial of higher dose before switching to a different medication
Prescribing pearls: desvenlafaxine (Pristiq) - effective for perimenopausal
vasomotor symptoms
considered when selecting a medication: - -Client preference
-Prior treatment response
