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ANCC FNP Exam Review – LEIK Part 1 Clinical Questions and Rationales (USA, 2025) – Diagnostic, Management, and Prevention Q&A

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This review document presents 50 high-yield clinical questions and evidence-based answer explanations based on LEIK’s FNP exam prep. It covers topics in pregnancy diagnostics, cardiovascular and respiratory murmurs, infectious diseases, dermatology, musculoskeletal conditions, hematology, preventive care, and pharmacology. Rationales include distinctions between signs, diagnostic criteria, and guideline-based management, making it ideal for reinforcing clinical judgment and exam readiness.

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Uploaded on
May 10, 2025
Number of pages
16
Written in
2024/2025
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ANCC FNP Exam Review Questions LEIK part 1

Key Concepts in Clinical Assessment and
Management
1. The Lachman Maneuver
 Indication: Detects instability of the knee.
 Incorrect Options:
o Nerve damage of the knee due to past injuries.
o Integrity of the patellar tendon.
o Tears of the meniscus.


2. Third Trimester Bleeding
 Clinical Presentation: A 28-year-old multipara at 32 weeks gestation with
sudden onset of small amounts of bright-red vaginal bleeding and a soft
uterus on palpation.
 Most Likely Diagnosis: Placenta previa.
 Differential Diagnoses (Less Likely):
o Placenta abruptio (typically presents with pain and a firm uterus).
o Acute cervicitis (usually associated with inflammation and discharge).
o Molar Pregnancy (hydatidiform mole) (typically presents earlier in
pregnancy with other signs).

3. Vaginal Discharge Analysis
 Key Findings:
o Large amount of milk-like vaginal discharge.
o Microscopy reveals numerous cells with blurred margins.
o Very few white blood cells.
o Vaginal pH of 6.0.
 Most Likely Diagnosis: Bacterial Vaginosis.
 Distinguishing Features (Incorrect Options):
o Trichomonas infections: Often present with motile trichomonads on
microscopy and a higher pH.

, o Candidal infection: Typically shows budding yeast and hyphae on
KOH prep, often with itching and a normal pH.
o Normal finding: The large amount of discharge and elevated pH are
not typical.

4. Signs and Symptoms of Depression
 Core Symptoms:
o Anhedonia (loss of interest or pleasure).
o Low Self-esteem.
o Apathy (lack of motivation or interest).
 Incorrect Option:
o Apraxia: A neurological disorder characterized by the inability to
perform learned (familiar) movements on command, even though the
command is understood and there is a willingness to perform the
movement.

5. Medicare Part B Coverage
 Covered Services:
o Persons aged 65 years or older.
o Durable medical equipment.
o Mammograms annually starting at age 50.
o Outpatient anesthesiologist services.
 Exception (Not Covered Under Part B): This question requires identifying
something not covered, which isn't explicitly listed in the correct options.
However, Part A primarily covers inpatient hospital stays, skilled nursing
facility care, hospice care, and some home health care.

6. Complications of Severe Preeclampsia
 Severe Preeclampsia Complications:
o Liver Failure.
o Hypertensive Encephalopathy.
o Pulmonary Edema.
 Incorrect Option:
o Placenta Previa: A condition where the placenta implants in the lower
part of the uterus, potentially covering the cervix. It is a risk factor for

, bleeding during pregnancy but not a direct complication of severe
preeclampsia.

7. Koplik's Spots
 Association: Rubeola (measles).
 Description: Small, white spots with bluish-white centers on an
erythematous background, found on the buccal mucosa.
 Incorrect Options:
o Poxvirus infections (e.g., smallpox, molluscum contagiosum).
o Kawasaki's disease (associated with fever, rash, conjunctivitis, etc.).
o Rubella (German measles, associated with a maculopapular rash
starting on the face).

8. Needlestick Injury Management
 Scenario: A middle-aged housekeeping worker sustains a needlestick injury
from an ER garbage bag.
 Next Step: Order an enzyme-linked immunosorbent assay (ELISA) test
as soon as possible to establish a baseline for potential bloodborne pathogen
exposure (HIV, Hepatitis B, Hepatitis C).
 Other Considerations:
o A tetanus booster should be considered based on the patient's
immunization history, but it's not the immediate next step for
bloodborne pathogen risk assessment.
o Hepatitis B immunoglobulin (HBIG) would be considered if the
source patient was known to be HBsAg positive or if the worker was
not vaccinated against Hepatitis B.
o A chest X-ray is not indicated for a needlestick injury.


9. Migraine Triggers - Incorrect Advice
 Common Migraine Triggers (Should Be Avoided):
o Foods high in tyramine content (e.g., aged cheeses, cured meats,
fermented foods).
o Get enough sleep (irregular sleep patterns can be a trigger).
o Fermented foods (often high in tyramine).
 Incorrect Advice (Should NOT Be Avoided):

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