PHARM CMS STUDY GUIDE REVISION
QUESTIONS CORRECTLY ANSWERED
What is the Opioid Toxicity Triad? - ANS Coma, respiratory depression, and pinpoint
pupils.
What drug is used to reverse opioid toxicity? - ANS Naloxone.
When do you administer the varicella vaccine? - ANS 1 dose: 12-15 months and 4-6
years
OR: 2 doses, 4 weeks apart if older than 13 years old.
What are contraindications to the varicella vaccine? - ANS Anaphylactic reaction to
gelatin or neomycin.
CANCER.
Ranolazine
- What is it used for?
- Interactions?
- What can you take it with? - ANS - Used with amlodipine for chronic stable angina.
- Cannot use with digoxin and simvastatin.
- Amlodipine
STATIN DRUGS (Simvastatin, Lovastatin, Pravastatin, Rosuvastatin, Fluvastatin,
Pitavastatin, Simvastatin + Ezetimibe)
- Complications?
- Avoid?
- What labs do you monitor? (6 levels/tests) - ANS - All statins are used to LOWER
LDL cholesterol.
- Complications: hepatotoxicity (evidenced by increased AST), myopathy (CK level).
- Avoid grapefruit juice.
- Baseline cholesterol, HDL, LDL, triglyceride levels, liver function tests, and kidney
function tests.
MYCIN DRUGS (Gentamicin, Tobramycin, Neomycin, Streptomycin, Paromomycin)
- What is it used for?
- Complications?
, - Interactions? - ANS - Used to treat gram-negative bacilli (E. Coli, UTI)
- Complications:
--> ototoxicity (tinnitus, headache, hearing loss, nausea, dizziness, vertigo)
--> nephrotoxicity (I&O, BUN, creatinine)
--> intense neuromuscular blockage (respiratory depression, muscle weakness)
--> Hypersensitivity
- Interactions: Penicillin, loop diuretics
-OLOL DRUGS (Metoprolol, Atenolol, Emolol, Propranolol, Nadolol, Carvedilol,
Labetalol)
- What is it used for?
- Complications?
- Contraindications/Precautions? - ANS - Used for primary hypertension, angina,
tachydysrhythmias, heart failure, and myocardial infarction.
- Complications: bradycardia (<50/min), decreased cardiac output (shortness of breath,
edema, weight gain, fatigue).
- Contraindicated for clients who have AV block, sinus bradycardia, asthma,
bronchospasm, heart failure. Use cautiously in patients with myasthenia Gravis,
hypotension, peripheral vascular disease, diabetes mellitus, depression, and severe
allergies.
What are 6 examples of calcium channel blockers? - ANS Nidefipine, Verapamil,
Diltiazem, Amlodipine, Felodipine, and Nicardipine.
When would you withhold calcium channel blockers? - ANS If their pulse is less than
50/min, and their systolic blood pressure is less than 90 mmHg.
Celecoxib: what does it do? - ANS Suppresses inflammation, relieves pain, decreases
fever, and can protect against colorectal cancer.
Celecoxib: What are complications? (6 total) - ANS - Gastrointestinal discomfort
- Impaired kidney function
- Increased risk of heart attacks and strokes.
- Salicylism (can occur with aspirin).
- Reye's Syndrome
- Aspirin toxicity
What are the signs and symptoms of Salicylism? (6 symptoms) - ANS Tinnitus,
sweating, headache, dizziness, respiratory alkalosis.
QUESTIONS CORRECTLY ANSWERED
What is the Opioid Toxicity Triad? - ANS Coma, respiratory depression, and pinpoint
pupils.
What drug is used to reverse opioid toxicity? - ANS Naloxone.
When do you administer the varicella vaccine? - ANS 1 dose: 12-15 months and 4-6
years
OR: 2 doses, 4 weeks apart if older than 13 years old.
What are contraindications to the varicella vaccine? - ANS Anaphylactic reaction to
gelatin or neomycin.
CANCER.
Ranolazine
- What is it used for?
- Interactions?
- What can you take it with? - ANS - Used with amlodipine for chronic stable angina.
- Cannot use with digoxin and simvastatin.
- Amlodipine
STATIN DRUGS (Simvastatin, Lovastatin, Pravastatin, Rosuvastatin, Fluvastatin,
Pitavastatin, Simvastatin + Ezetimibe)
- Complications?
- Avoid?
- What labs do you monitor? (6 levels/tests) - ANS - All statins are used to LOWER
LDL cholesterol.
- Complications: hepatotoxicity (evidenced by increased AST), myopathy (CK level).
- Avoid grapefruit juice.
- Baseline cholesterol, HDL, LDL, triglyceride levels, liver function tests, and kidney
function tests.
MYCIN DRUGS (Gentamicin, Tobramycin, Neomycin, Streptomycin, Paromomycin)
- What is it used for?
- Complications?
, - Interactions? - ANS - Used to treat gram-negative bacilli (E. Coli, UTI)
- Complications:
--> ototoxicity (tinnitus, headache, hearing loss, nausea, dizziness, vertigo)
--> nephrotoxicity (I&O, BUN, creatinine)
--> intense neuromuscular blockage (respiratory depression, muscle weakness)
--> Hypersensitivity
- Interactions: Penicillin, loop diuretics
-OLOL DRUGS (Metoprolol, Atenolol, Emolol, Propranolol, Nadolol, Carvedilol,
Labetalol)
- What is it used for?
- Complications?
- Contraindications/Precautions? - ANS - Used for primary hypertension, angina,
tachydysrhythmias, heart failure, and myocardial infarction.
- Complications: bradycardia (<50/min), decreased cardiac output (shortness of breath,
edema, weight gain, fatigue).
- Contraindicated for clients who have AV block, sinus bradycardia, asthma,
bronchospasm, heart failure. Use cautiously in patients with myasthenia Gravis,
hypotension, peripheral vascular disease, diabetes mellitus, depression, and severe
allergies.
What are 6 examples of calcium channel blockers? - ANS Nidefipine, Verapamil,
Diltiazem, Amlodipine, Felodipine, and Nicardipine.
When would you withhold calcium channel blockers? - ANS If their pulse is less than
50/min, and their systolic blood pressure is less than 90 mmHg.
Celecoxib: what does it do? - ANS Suppresses inflammation, relieves pain, decreases
fever, and can protect against colorectal cancer.
Celecoxib: What are complications? (6 total) - ANS - Gastrointestinal discomfort
- Impaired kidney function
- Increased risk of heart attacks and strokes.
- Salicylism (can occur with aspirin).
- Reye's Syndrome
- Aspirin toxicity
What are the signs and symptoms of Salicylism? (6 symptoms) - ANS Tinnitus,
sweating, headache, dizziness, respiratory alkalosis.
