UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
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m m m m m m
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m m m m m m m
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m
Chapter m01:mCellular mBiology
MULTIPLEmCHOICE
1. A mstudent mismobservingmamcellmundermthemmicroscope.mIt mismobserved mtomhavemsupercoiled mD
NAmwithmhistones.mWhichmof mthemfollowingmwould malsombemobserved mbymthemstudent?ma.mAms
inglemcircularmchromosome
b. Amnucleus
c. Free-floatingmnuclearmmaterial
d. Nomorganelles
ANS:mB
Themcellmdescribed mismameukaryoticmcell,mso mit mhasmhistonesmand mamsupercoiled mDNA mwithinmitsmnu
cleus;mthus,mthemnucleusmshould mbemobserved.mAmsinglemcircularmchromosomemcalled mamprokaryote
mcontainsmfree-floatingmnuclearmmaterialmbut mhasmnomorganelles.
REF:mp.m2
2. A mnursemisminstructingmthemstaff mabout mcellularmfunctions.mWhichmcellularmfunctionmis mthemnur
semdescribingmwhenmanmisolated mcellmabsorbsmoxygenmand musesmit mtomtransformmnutrientsmtomen
ergy?
a. Metabolicmabsorption
b. Communication
c. Secretion
d. Respiration
ANS:mD NURSINGTB.COM
Themcell’smabilitymtomabsorbmoxygenmismreferred mtomasmrespirationmwhilem itsmcommunicationmabilityminvo
lvesmmaintenancemof mamsteadymdynamicmstate,mmetabolicmabsorptionmprovidesmnutrition,mand msecretionmal
lowsmformthemsynthesizingmof mnew msubstances.
REF:mp.m2
3. A meukaryoticmcellmismundergoingmDNA mreplication.mInmwhichmregionmof mthemcellmwould mmost mof m
themgeneticminformationmbemcontained?
a. Mitochondria
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, UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
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b. Ribosome
c. Nucleolus
d. NucleusmCytoplasm
ANS:mC
Themregionmof mthemcellmthat mcontainsmgeneticmmaterial,mincludingmam large mamount mof mribonucleic m
acid,mmost mof mthemDNA,mand mDNA-
bindingmproteins,mismthemnucleolus,mwhichmismlocated mwithinmthemcell’smnucleus.mMitochondriamis m
associated mwithmcellularmrespiration,mwhilemribosomesmareminvolved mwithmproteinmmanufacturing
.mCytoplasmmismamfluid mfillingmthat mismamcomponent mof mthemcell.
REF:mp.m2
4. Whichmof mthemfollowingmcanmremovemproteinsmattached mtomthemcell’smbilayermbymdissolvingmthemlayer
itself?
a. Peripheralmmembranemproteins
b. Integralmmembranemproteins
c. Glycoproteins
d. Cellmadhesionmmolecules
ANS:mB
Proteinsmdirectlymattached mtomthemmembranembilayermcanmbemremoved mbymthemactionmof mintegralm
membranemproteinsmthat mdissolvemthembilayer.mPeripheralmmembranemproteinsm residemat mthemsurf
acemwhilemcellmadhesionmmoleculesmaremonmthemoutsidemof mthemmembrane.mGlycoproteinmmarksmc
ellsmand mdoesmnot mfloat.
REF:mp.m7
5. Whichmof mthemfollowingmcanmbind mtomplasmammembranemreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicmlipids
d. Ligands
ANS:mD
Ligandsmaremthemonlymspecificmmoleculesmthat mcanmbind mwithmreceptorsmonmthemcellmmembrane.
REF:mp.m9
6. A mnursemismreviewingmamreport mfrommampatient mwithmmetastaticmcancer.mWhat malternationminmthe
extracellularmmatrixmwould msupport mthemdiagnosismof mmetastaticmcancer?a. NURSINGTB.COM
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, UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
k mfibronectin
Decreased
b. Increased mcollagen
c. Decreased melastin
d. Increased mglycoproteins
ANS:mA
Onlymamreduced mamount mof mfibronectinmismfound minmsomemtypesmof mcancerousmcells,mallowingmth
emmtomtravelmormmetastasize.
REF:mp.m10
7. Whichmformmof mcellmcommunicationmismused mtomrelatemtomothermcellsminmdirect mphysicalmcontact?ma.m
Cellmjunction
b. Gapmjunction
c. Desmosome
d. Tight mjunction
ANS:mA
Cellmjunctionsmhold mcellsmtogethermand mpermit mmoleculesmtompassmfrommcellmtomcell.
Gapmjunctionsmallow mformcellularmcommunicationmbetweenmcells.mNeithermdesmosomesmnormtight mjunction
smaremassociated mwithmcellularmcommunication.
REF:mp.m11
8. Pancreaticmbetamcellsmsecreteminsulin,mwhichminhibitsmsecretionmof mglucagonmfrommneighboringmalp
hamcells.mThismactionmismanmexamplemof mwhichmof mthemfollowingmsignalingmtypes?ma.mParacrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:mA
Paracrinemsignalingminvolvesmthemreleasemof mlocalmchemicalm mediatorsmthat maremquickly mtakenmup,mdestr
oyed,mormimmobilized,masminmthemcasemof minsulinmand mtheminhibitionmof mthemsecretionmof mglucagon.mNone
mof mthemothermoptionsminvolvemsignalingmthat mismassociated mwithmamlocalmchemicalm mediatormlikem insulin.
REF:mp.m12
9. Inmcellularmmetabolism,meachmenzymemhasmamhighmaffinitymforma:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
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ANS:mB
Eachmenzymemhasmamhighmaffinitymformamsubstrate,mamspecificmsubstancemconverted mtomamproduct
mof mthemreaction.mCellularmmetabolismmismnot mdependent monmanmattractionmbetweenmanmenzyme
mand manymof mthemremainingmoptions.
REF:mp.m16
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10. Anmathletemrunsmammarathon,maftermwhichmhismmusclesmfeelmfatigued mand munablemtomcontract.mThema
thletemasksmthemnursemwhymthismhappened.mThemnurse’smresponsemismbased monmthemknowledgemthat mt
hemproblemmismresult mof mamdeficiencymof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:mC
WhenmATPmismdeficient,mimpaired mmusclemcontractionmresults.mNonemof mthemothermoptionsmareminvolve
d minmmusclemcontraction.
REF:mp.m16
11. Whichmphasemof mcatabolismmproducesmthemmost mATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricmacid mcycle
ANS:mD
WhilemsomemATPmismproduced mduringmthemoxidationmand mglycolysismphases,mmost mof mthemATPmismgenerat
mduringmthemcitricmacid mcycle.mDigestionmdoesmnot mproducemanymATP.
REF:mp.m16
12. Amnursemismteachingmthemstaff mabout mthemphasesmof mcellularmcatabolism.mWhichmphasesmshould mthemnu
rseminclude?
a. Digestion,mglycolysis,moxidation,mand mthemcitricmacid mcycle
b. Diffusion,mosmosis,mand mmediated mtransport
c. Smphase,mG mphase,mand mMmphase
d. Metabolicmabsorption,mrespiration,mand mexcretion
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Understanding Pathophysiology, 6th Edition 2023 EXAM
m m m m m m
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m m m m m m m
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m
Chapter m01:mCellular mBiology
MULTIPLEmCHOICE
1. A mstudent mismobservingmamcellmundermthemmicroscope.mIt mismobserved mtomhavemsupercoiled mD
NAmwithmhistones.mWhichmof mthemfollowingmwould malsombemobserved mbymthemstudent?ma.mAms
inglemcircularmchromosome
b. Amnucleus
c. Free-floatingmnuclearmmaterial
d. Nomorganelles
ANS:mB
Themcellmdescribed mismameukaryoticmcell,mso mit mhasmhistonesmand mamsupercoiled mDNA mwithinmitsmnu
cleus;mthus,mthemnucleusmshould mbemobserved.mAmsinglemcircularmchromosomemcalled mamprokaryote
mcontainsmfree-floatingmnuclearmmaterialmbut mhasmnomorganelles.
REF:mp.m2
2. A mnursemisminstructingmthemstaff mabout mcellularmfunctions.mWhichmcellularmfunctionmis mthemnur
semdescribingmwhenmanmisolated mcellmabsorbsmoxygenmand musesmit mtomtransformmnutrientsmtomen
ergy?
a. Metabolicmabsorption
b. Communication
c. Secretion
d. Respiration
ANS:mD NURSINGTB.COM
Themcell’smabilitymtomabsorbmoxygenmismreferred mtomasmrespirationmwhilem itsmcommunicationmabilityminvo
lvesmmaintenancemof mamsteadymdynamicmstate,mmetabolicmabsorptionmprovidesmnutrition,mand msecretionmal
lowsmformthemsynthesizingmof mnew msubstances.
REF:mp.m2
3. A meukaryoticmcellmismundergoingmDNA mreplication.mInmwhichmregionmof mthemcellmwould mmost mof m
themgeneticminformationmbemcontained?
a. Mitochondria
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, UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
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b. Ribosome
c. Nucleolus
d. NucleusmCytoplasm
ANS:mC
Themregionmof mthemcellmthat mcontainsmgeneticmmaterial,mincludingmam large mamount mof mribonucleic m
acid,mmost mof mthemDNA,mand mDNA-
bindingmproteins,mismthemnucleolus,mwhichmismlocated mwithinmthemcell’smnucleus.mMitochondriamis m
associated mwithmcellularmrespiration,mwhilemribosomesmareminvolved mwithmproteinmmanufacturing
.mCytoplasmmismamfluid mfillingmthat mismamcomponent mof mthemcell.
REF:mp.m2
4. Whichmof mthemfollowingmcanmremovemproteinsmattached mtomthemcell’smbilayermbymdissolvingmthemlayer
itself?
a. Peripheralmmembranemproteins
b. Integralmmembranemproteins
c. Glycoproteins
d. Cellmadhesionmmolecules
ANS:mB
Proteinsmdirectlymattached mtomthemmembranembilayermcanmbemremoved mbymthemactionmof mintegralm
membranemproteinsmthat mdissolvemthembilayer.mPeripheralmmembranemproteinsm residemat mthemsurf
acemwhilemcellmadhesionmmoleculesmaremonmthemoutsidemof mthemmembrane.mGlycoproteinmmarksmc
ellsmand mdoesmnot mfloat.
REF:mp.m7
5. Whichmof mthemfollowingmcanmbind mtomplasmammembranemreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicmlipids
d. Ligands
ANS:mD
Ligandsmaremthemonlymspecificmmoleculesmthat mcanmbind mwithmreceptorsmonmthemcellmmembrane.
REF:mp.m9
6. A mnursemismreviewingmamreport mfrommampatient mwithmmetastaticmcancer.mWhat malternationminmthe
extracellularmmatrixmwould msupport mthemdiagnosismof mmetastaticmcancer?a. NURSINGTB.COM
NURSINGTB.COM
, UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
k mfibronectin
Decreased
b. Increased mcollagen
c. Decreased melastin
d. Increased mglycoproteins
ANS:mA
Onlymamreduced mamount mof mfibronectinmismfound minmsomemtypesmof mcancerousmcells,mallowingmth
emmtomtravelmormmetastasize.
REF:mp.m10
7. Whichmformmof mcellmcommunicationmismused mtomrelatemtomothermcellsminmdirect mphysicalmcontact?ma.m
Cellmjunction
b. Gapmjunction
c. Desmosome
d. Tight mjunction
ANS:mA
Cellmjunctionsmhold mcellsmtogethermand mpermit mmoleculesmtompassmfrommcellmtomcell.
Gapmjunctionsmallow mformcellularmcommunicationmbetweenmcells.mNeithermdesmosomesmnormtight mjunction
smaremassociated mwithmcellularmcommunication.
REF:mp.m11
8. Pancreaticmbetamcellsmsecreteminsulin,mwhichminhibitsmsecretionmof mglucagonmfrommneighboringmalp
hamcells.mThismactionmismanmexamplemof mwhichmof mthemfollowingmsignalingmtypes?ma.mParacrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:mA
Paracrinemsignalingminvolvesmthemreleasemof mlocalmchemicalm mediatorsmthat maremquickly mtakenmup,mdestr
oyed,mormimmobilized,masminmthemcasemof minsulinmand mtheminhibitionmof mthemsecretionmof mglucagon.mNone
mof mthemothermoptionsminvolvemsignalingmthat mismassociated mwithmamlocalmchemicalm mediatormlikem insulin.
REF:mp.m12
9. Inmcellularmmetabolism,meachmenzymemhasmamhighmaffinitymforma:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
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, UnderstandingmPathophysiologym6thmEditionmHuethermTest mBan
k
ANS:mB
Eachmenzymemhasmamhighmaffinitymformamsubstrate,mamspecificmsubstancemconverted mtomamproduct
mof mthemreaction.mCellularmmetabolismmismnot mdependent monmanmattractionmbetweenmanmenzyme
mand manymof mthemremainingmoptions.
REF:mp.m16
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10. Anmathletemrunsmammarathon,maftermwhichmhismmusclesmfeelmfatigued mand munablemtomcontract.mThema
thletemasksmthemnursemwhymthismhappened.mThemnurse’smresponsemismbased monmthemknowledgemthat mt
hemproblemmismresult mof mamdeficiencymof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:mC
WhenmATPmismdeficient,mimpaired mmusclemcontractionmresults.mNonemof mthemothermoptionsmareminvolve
d minmmusclemcontraction.
REF:mp.m16
11. Whichmphasemof mcatabolismmproducesmthemmost mATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricmacid mcycle
ANS:mD
WhilemsomemATPmismproduced mduringmthemoxidationmand mglycolysismphases,mmost mof mthemATPmismgenerat
mduringmthemcitricmacid mcycle.mDigestionmdoesmnot mproducemanymATP.
REF:mp.m16
12. Amnursemismteachingmthemstaff mabout mthemphasesmof mcellularmcatabolism.mWhichmphasesmshould mthemnu
rseminclude?
a. Digestion,mglycolysis,moxidation,mand mthemcitricmacid mcycle
b. Diffusion,mosmosis,mand mmediated mtransport
c. Smphase,mG mphase,mand mMmphase
d. Metabolicmabsorption,mrespiration,mand mexcretion
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