Quiz Set | Verified 100% Correct
CYP enzymes involved in psychiatric drug metabolism - CYP3A4, CYP2D6, CYP2C19, and
CYP1A2.
Effect of enzyme inhibitors on drug metabolism - Inhibitors slow down drug metabolism,
which leads to increased drug levels.
Example of an enzyme inhibitor - Fluoxetine is an enzyme inhibitor that decreases drug
metabolism.
Effect of enzyme inducers on drug metabolism - Inducers speed up drug metabolism,
leading to decreased drug levels.
Example of an enzyme inducer - Omeprazole is an enzyme inducer that increases drug
metabolism. (lowering drug levels)
Agonist in pharmacology - An agonist activates a receptor and causes an effect, such as
SSRIs increasing serotonin activity.
Antagonist in pharmacology - An antagonist blocks a receptor and prevents an effect,
such as antipsychotics blocking dopamine.
Therapeutic index (TI) of a drug - The therapeutic index is the ratio of the effective dose
to the toxic dose of a drug.
Therapeutic range for lithium - Lithium's therapeutic range is 0.6-1.2 mEq/L, and levels
above 1.5 mEq/L are considered toxic.
Main roles of dopamine in the brain - Dopamine is involved in mood, reward, and
movement regulation.
Primary function of serotonin - Serotonin regulates mood, sleep, and appetite.
Neurotransmitter responsible for inhibition in the brain - GABA (gamma-aminobutyric
acid) is the primary inhibitory neurotransmitter.
Primary excitatory neurotransmitter in the brain - Glutamate is the primary excitatory
neurotransmitter.