Test Bank
,Chapter 1: Drug Definitions, Standards, and Information Sources Test Bank
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which
section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this
drug?
a. Manufacturer’s section
b. Brand and Generic Name section
c. Product Category section
d. Product Information section
ANS: B
DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4TOP:
Nursing Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
5. Which online drug reference makes available to health care providers and the public a
standard, comprehensive, up to date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Physicians’ Desk Reference (PDR)
ANS: C
DailyMed makes available to health care providers and the public a standard, comprehensive,
up to date look up and downloadable resource about medicines. The American Drug Index is
not appropriate for patient use. The American Hospital Formulary is not appropriate for
patient use. The PDR is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 5TOP: Nursing
Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
cannot be used safely without medical supervision and restricts their sale to prescription by a
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 8TOP: Nursing
, Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
dependency. Under which classification does this drug fall?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
drugs have low potential for abuse. Use may lead to limited physical or psychological
dependence.
DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
8. What would the FDA do to expedite drug development and approval for an outbreak of
smallpox, for which there is no known treatment?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
become a priority concern in the world. Orphan diseases are not researched in a priority
manner. Preclinical research is not omitted. Extending any phase of the research would mean
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
clinical research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 8TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
9. Which statement is true about over the counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a health care provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and trade,
can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription
drugs require an order by a health professional who is licensed to prescribe, such as a
physician, nurse practitioner, physician assistant, or dentist.
, DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2TOP:
Nursing Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
10. Which is the most authoritative reference for medications that are injected?
e. Physician’s Desk Reference
f. Handbook on Injectable Drugs
g. DailyMed
h. Handbook of Nonprescription Drugs
ANS: B
The Handbook on Injectable Drugs is the most comprehensive reference available on the
topic of compatibility of injectable drugs. It is a collection of monographs for more than 300
injectable drugs that are listed alphabetically by generic name.
DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
10. The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this
drug’s classification?
a. Abuse potential for this drug is low.
b. Psychological dependency is likely.
c. There is a high potential for abuse.
d. This drug is not a controlled substance.
ANS: A
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
dependence liability compared with drugs in Schedule IV. Because abuse potential is low with
a Schedule V drug, a prescription may not be required. Psychological dependency is not likely
with a Schedule V drug. Schedule V drugs are classified as controlled substances.
DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 7TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
11. The nurse is transcribing new orders written for a patient with a substance abuse history.
Choose the medication ordered that has the greatest risk for abuse.
a. Lomotil
b. Diazepam
c. Phenobarbital
d. Lortab
ANS: D
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in
Schedules I and II. Lomotil is a Schedule V drug with a low potential for abuse compared
with those in Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse
compared with those in schedule III. Phenobarbital is a Schedule IV drug with a low potential
for abuse compared with those in Schedule III.
DIF: Cognitive Level: Application REF: pp. 4-5 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
,MULTIPLE RESPONSE
12. The nurse is caring for a patient newly diagnosed with type 1 diabetes mellitus. Which
approach(es) to therapeutic methods would be considered in this patient’s treatment? (Select
all that apply.)
a. Therapeutic drugs
b. Concentrated carbohydrate diet
c. Family centered care
d. Regular daily exercise and activity
e. Daily baths
ANS: A, B, D
Therapeutic methods include drug therapy, diet therapy, physiotherapy, and psychological
therapy. Therapeutic methods do not include family centered care or daily baths.
DIF: Cognitive Level: Application REF: p. 1 OBJ: 1TOP: Nursing
Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
13. An older adult experiencing shortness of breath is brought to the hospital by her daughter.
While obtaining the medication history from the patient and her daughter, the nurse discovers
that neither has a list of the patient’s current medications or prescriptions. All the patient has
is a weekly pill dispenser that contains four different pills. The prescriptions are filled through
the local pharmacy. Which resource(s) would be appropriate to use in determining the
medication names and doses? (Select all that apply.)
a. Martindale—The Complete Drug Reference
b. Physicians’ Desk Reference, Section 4
c. Senior citizens’ center
d. Patient’s home pharmacy
ANS: B, D
The Physicians’ Desk Reference, Section 4, has full color images of commonly dispensed
tablets and capsules. The patient’s pharmacy would have an accurate account of all the
medications the client is currently taking. Martindale—The Complete Drug Reference has
written information on medications and would not be an appropriate resource. The senior
citizens’ center is not likely to have specific patient medication information.
DIF: Cognitive Level: Application REF: p. 3 OBJ: 3 | 4TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
14. The nurse planning patient teaching regarding drug names would include which statement(s)?
(Select all that apply.)
a. Most drug companies place their products on the market under generic names.
b. The official name is the name under which the drug is listed by the U.S. Food and
Drug Administration (FDA).
c. Brand names are easier to pronounce, spell, and remember.
d. The first letter of the generic name is not capitalized.
e. The chemical name is most meaningful to the patient.
ANS: B, C, D
The official name is the name under which the drug is listed by the FDA. Brand names are
easier to pronounce, spell, and remember. The first letter of the generic name is not
capitalized. Most drug companies place their products on the market under brand names
, instead of generic names. The chemical name is most meaningful to the chemist.
DIF: Cognitive Level: Application REF: p. 1 OBJ: 2TOP: Nursing
Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
15. When categorizing, the nurse is aware that which drug(s) would be considered Schedule II?
(Select all that apply.)
a. Marijuana
b. Percodan
c. Amphetamines
d. Fiorinal
e. Flurazepam
ANS: B, C
Schedule II drugs have a high potential for abuse, they are currently accepted in the United
States, and use may lead to severe psychological or physical dependence. Percodan and
amphetamines are considered Schedule II drugs. Marijuana is a Schedule I drug. Fiorinal is a
Schedule III drug. Flurazepam is a Schedule IV drug.
DIF: Cognitive Level: Analysis REF: pp. 4-5 OBJ: 7TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
Chapter 2: Basic Principles of Drug Action and Drug InteractionsTest
Bank
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is the nurse’s priority
action?
a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
which are easily identified. An idiosyncratic reaction occurs when something unusual or
abnormal happens when a drug is first administered. A teratogenic reaction refers to the
occurrence of birth defects related to administration of the drug. Tolerance refers to the body’s
requirement for increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: p. 17 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
,2. The mnurse madministers man minitial mdose mof ma msteroid mto ma mpatient mwith masthma. mThirty
mminutes mafter madministration, mthe mnurse mfinds mthe mpatient magitated mand mstating mthat
m“everyone mis mout mto mget mme.” mWhat mis mthe mterm mfor mthis munusual mreaction?
a. Desired maction
b. Adverse meffect
c. Idiosyncratic mreaction
d. Allergic mreaction
ANS: m C
Idiosyncratic mreactions mare munusual, mabnormal mreactions mthat moccur mwhen ma mdrug mis mfirst
madministered. mPatients mtypically mexhibit man moverresponsiveness mto ma mmedication mrelated
mto mdiminished mmetabolism. mThese mreactions mare mbelieved mto mbe mrelated mto mgenetic
menzyme mdeficiencies. mDesired mactions mare mexpected mresponses mto ma mmedication. mAdverse
meffects mare mreactions mthat moccur min manother msystem mof mthe mbody; mthey mare musually
mpredictable. mAllergic mreactions mappear mafter mrepeated mmedication mdosages.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m7TOP:
Nursing mProcess mStep: mEvaluation
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
3. Which mis mthe mbest mdescription mof mwhen mdrug minteractions moccur?
a. On madministration mof mtoxic mdosages mof ma mdrug
b. On man mincrease min mthe mpharmacodynamics mof mbound mdrugs
c. On mthe malteration mof mthe meffect mof mone mdrug mby manother mdrug
d. On mincrease mof mdrug mexcretion
ANS: m C
Drug minteractions mmay mbe mcharacterized mby man mincrease mor mdecrease min mthe
meffectiveness mof moneor mboth mof mthe mdrugs. mToxicity mof mone mdrug mmay mor mmay mnot
maffect mthe mmetabolism mof manother mone. mDrug minteractions mmay mresult mfrom meither
mincreased mor mdecreased mpharmacodynamics.
Drug minteractions mmay mresult mfrom meither mincreased mor mdecreased mexcretion.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m8TOP:
Nursing mProcess mStep: mAssessment
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
4. What moccurs mwhen mtwo mdrugs mcompete mfor mthe msame mreceptor msite, mresulting min
mincreased mactivity mof mthe mfirst mdrug?
a. Desired maction
b. Synergistic meffect
c. Carcinogenicity
d. Displacement
ANS: m D
The mdisplacement mof mthe mfirst mdrug mfrom mreceptor msites mby ma msecond mdrug mincreases mthe
mamount mof mthe mfirst mdrug mbecause mmore munbound mdrug mis mavailable. mAn mexpected
mresponse mof ma mdrug mis mthe mdesired maction. mA msynergistic meffect mis mthe meffect mof mtwo
mdrugs mbeing mgreater mthan mthe meffect mof meach mchemical mindividually, mor mthe msum mof mthe
mindividual meffects. mCarcinogenicity mis mthe mability mof ma mdrug mto mcause mcells mto mmutate
mand mbecome mcancerous.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m9TOP:
mNursing mProcess mStep: mImplementation
, MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
5. What mdo mdrug mblood mlevels mindicate?
a. They mconfirm mif mthe mpatient mis mtaking ma mgeneric mform mof ma mdrug.
b. They mdetermine mif mthe mpatient mhas msufficient mbody mfat mto mmetabolize mthe mdrug.
c. They mverify mif mthe mpatient m is mtaking msomeone melse’s mmedications.
d. They mdetermine mif mthe mamount mof mdrug min mthe mbody mis min ma mtherapeutic mrange.
ANS: m D
The mamount mof mdrug mpresent mmay mvary mover mtime mand mthe mblood mlevel mmust mremain min ma
therapeutic mrange min morder mto mobtain mthe mdesired c. Drug
mresult. mGeneric mdrugs mdo mnot mnecessarily mproduce ma
d. Therapeuti
mdifferent mdrug mblood mlevel mthan mproprietary c
mmedications. mBody mfat mis mnot mmeasured mby mdrug ANS: m C
mblood mlevels. mDrug mblood mlevels monly mmeasure mthe When
mamount mof mdrug min mthe mbody; mthey mdonot mdetermine ma
mthe msource mof mthe mmedication. mdrug
mis
DIF: mCognitive mLevel: mComprehension mREF: mp. m16 mOBJ: mcircul
m7TOP: mNursing mProcess mStep: mEvaluation ating
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological min
mIntegrity mthe
mblood
6. What mis mthe mprocess mby mwhich ma mdrug mis mtransported mby , ma
mcirculating mbody mfluids mto mreceptor msites? mblood
a. Osmosis msampl
b. Distribution e mmay
c. Absorption mbe
d. Biotransformation mdraw
ANS: m B n mand
massay
Distribution mrefers mto mthe mways min mwhich mdrugs mare ed mto
mtransported mby mthe mcirculating mbody mfluids mtothe msites
mdeter
mof maction m(receptors), mmetabolism, mand mexcretion.
mine
mOsmosis mis mthe mprocess mof mmovingsolution macross ma
mthe
msemipermeable mmembrane mto mequalize mthe mdilution mon
mamou
meach mside.
nt mof
Absorption mis mthe mprocess mby mwhich ma mdrug mis mdrug
mtransferred mfrom mits msite mof mentry minto mthe mbody mto
mprese
mthe mcirculating mfluids mfor mdistribution.
nt;
mBiotransformation, malso mcalled mmetabolism, mis mthe
mthis
mprocess mbywhich mthe mbody minactivates mdrugs.
mis
mknow
DIF: mCognitive mLevel: mComprehension mREF: mp. m13 mOBJ: n mas
m4TOP: mNursing mProcess mStep: mPlanning
mthe
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mdrug
mIntegrity
mblood
mlevel.
7. The mnurse massesses mwhich mblood mlevel mto mPeak
mdetermine mthe mamount mof mcirculating mmedication mlevels
min mapatient? mare
a. Peak monly
b. Trough mthose
,Chapter 1: Drug Definitions, Standards, and Information Sources Test Bank
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which
section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this
drug?
a. Manufacturer’s section
b. Brand and Generic Name section
c. Product Category section
d. Product Information section
ANS: B
DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4TOP:
Nursing Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
5. Which online drug reference makes available to health care providers and the public a
standard, comprehensive, up to date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Physicians’ Desk Reference (PDR)
ANS: C
DailyMed makes available to health care providers and the public a standard, comprehensive,
up to date look up and downloadable resource about medicines. The American Drug Index is
not appropriate for patient use. The American Hospital Formulary is not appropriate for
patient use. The PDR is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 5TOP: Nursing
Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
cannot be used safely without medical supervision and restricts their sale to prescription by a
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 8TOP: Nursing
, Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
dependency. Under which classification does this drug fall?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
drugs have low potential for abuse. Use may lead to limited physical or psychological
dependence.
DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
8. What would the FDA do to expedite drug development and approval for an outbreak of
smallpox, for which there is no known treatment?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
become a priority concern in the world. Orphan diseases are not researched in a priority
manner. Preclinical research is not omitted. Extending any phase of the research would mean
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
clinical research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 8TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
9. Which statement is true about over the counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a health care provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and trade,
can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription
drugs require an order by a health professional who is licensed to prescribe, such as a
physician, nurse practitioner, physician assistant, or dentist.
, DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2TOP:
Nursing Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
10. Which is the most authoritative reference for medications that are injected?
e. Physician’s Desk Reference
f. Handbook on Injectable Drugs
g. DailyMed
h. Handbook of Nonprescription Drugs
ANS: B
The Handbook on Injectable Drugs is the most comprehensive reference available on the
topic of compatibility of injectable drugs. It is a collection of monographs for more than 300
injectable drugs that are listed alphabetically by generic name.
DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
10. The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this
drug’s classification?
a. Abuse potential for this drug is low.
b. Psychological dependency is likely.
c. There is a high potential for abuse.
d. This drug is not a controlled substance.
ANS: A
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
dependence liability compared with drugs in Schedule IV. Because abuse potential is low with
a Schedule V drug, a prescription may not be required. Psychological dependency is not likely
with a Schedule V drug. Schedule V drugs are classified as controlled substances.
DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 7TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
11. The nurse is transcribing new orders written for a patient with a substance abuse history.
Choose the medication ordered that has the greatest risk for abuse.
a. Lomotil
b. Diazepam
c. Phenobarbital
d. Lortab
ANS: D
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in
Schedules I and II. Lomotil is a Schedule V drug with a low potential for abuse compared
with those in Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse
compared with those in schedule III. Phenobarbital is a Schedule IV drug with a low potential
for abuse compared with those in Schedule III.
DIF: Cognitive Level: Application REF: pp. 4-5 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
,MULTIPLE RESPONSE
12. The nurse is caring for a patient newly diagnosed with type 1 diabetes mellitus. Which
approach(es) to therapeutic methods would be considered in this patient’s treatment? (Select
all that apply.)
a. Therapeutic drugs
b. Concentrated carbohydrate diet
c. Family centered care
d. Regular daily exercise and activity
e. Daily baths
ANS: A, B, D
Therapeutic methods include drug therapy, diet therapy, physiotherapy, and psychological
therapy. Therapeutic methods do not include family centered care or daily baths.
DIF: Cognitive Level: Application REF: p. 1 OBJ: 1TOP: Nursing
Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
13. An older adult experiencing shortness of breath is brought to the hospital by her daughter.
While obtaining the medication history from the patient and her daughter, the nurse discovers
that neither has a list of the patient’s current medications or prescriptions. All the patient has
is a weekly pill dispenser that contains four different pills. The prescriptions are filled through
the local pharmacy. Which resource(s) would be appropriate to use in determining the
medication names and doses? (Select all that apply.)
a. Martindale—The Complete Drug Reference
b. Physicians’ Desk Reference, Section 4
c. Senior citizens’ center
d. Patient’s home pharmacy
ANS: B, D
The Physicians’ Desk Reference, Section 4, has full color images of commonly dispensed
tablets and capsules. The patient’s pharmacy would have an accurate account of all the
medications the client is currently taking. Martindale—The Complete Drug Reference has
written information on medications and would not be an appropriate resource. The senior
citizens’ center is not likely to have specific patient medication information.
DIF: Cognitive Level: Application REF: p. 3 OBJ: 3 | 4TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
14. The nurse planning patient teaching regarding drug names would include which statement(s)?
(Select all that apply.)
a. Most drug companies place their products on the market under generic names.
b. The official name is the name under which the drug is listed by the U.S. Food and
Drug Administration (FDA).
c. Brand names are easier to pronounce, spell, and remember.
d. The first letter of the generic name is not capitalized.
e. The chemical name is most meaningful to the patient.
ANS: B, C, D
The official name is the name under which the drug is listed by the FDA. Brand names are
easier to pronounce, spell, and remember. The first letter of the generic name is not
capitalized. Most drug companies place their products on the market under brand names
, instead of generic names. The chemical name is most meaningful to the chemist.
DIF: Cognitive Level: Application REF: p. 1 OBJ: 2TOP: Nursing
Process Step: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity
15. When categorizing, the nurse is aware that which drug(s) would be considered Schedule II?
(Select all that apply.)
a. Marijuana
b. Percodan
c. Amphetamines
d. Fiorinal
e. Flurazepam
ANS: B, C
Schedule II drugs have a high potential for abuse, they are currently accepted in the United
States, and use may lead to severe psychological or physical dependence. Percodan and
amphetamines are considered Schedule II drugs. Marijuana is a Schedule I drug. Fiorinal is a
Schedule III drug. Flurazepam is a Schedule IV drug.
DIF: Cognitive Level: Analysis REF: pp. 4-5 OBJ: 7TOP: Nursing
Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
Chapter 2: Basic Principles of Drug Action and Drug InteractionsTest
Bank
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is the nurse’s priority
action?
a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
which are easily identified. An idiosyncratic reaction occurs when something unusual or
abnormal happens when a drug is first administered. A teratogenic reaction refers to the
occurrence of birth defects related to administration of the drug. Tolerance refers to the body’s
requirement for increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: p. 17 OBJ: 7TOP:
Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
,2. The mnurse madministers man minitial mdose mof ma msteroid mto ma mpatient mwith masthma. mThirty
mminutes mafter madministration, mthe mnurse mfinds mthe mpatient magitated mand mstating mthat
m“everyone mis mout mto mget mme.” mWhat mis mthe mterm mfor mthis munusual mreaction?
a. Desired maction
b. Adverse meffect
c. Idiosyncratic mreaction
d. Allergic mreaction
ANS: m C
Idiosyncratic mreactions mare munusual, mabnormal mreactions mthat moccur mwhen ma mdrug mis mfirst
madministered. mPatients mtypically mexhibit man moverresponsiveness mto ma mmedication mrelated
mto mdiminished mmetabolism. mThese mreactions mare mbelieved mto mbe mrelated mto mgenetic
menzyme mdeficiencies. mDesired mactions mare mexpected mresponses mto ma mmedication. mAdverse
meffects mare mreactions mthat moccur min manother msystem mof mthe mbody; mthey mare musually
mpredictable. mAllergic mreactions mappear mafter mrepeated mmedication mdosages.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m7TOP:
Nursing mProcess mStep: mEvaluation
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
3. Which mis mthe mbest mdescription mof mwhen mdrug minteractions moccur?
a. On madministration mof mtoxic mdosages mof ma mdrug
b. On man mincrease min mthe mpharmacodynamics mof mbound mdrugs
c. On mthe malteration mof mthe meffect mof mone mdrug mby manother mdrug
d. On mincrease mof mdrug mexcretion
ANS: m C
Drug minteractions mmay mbe mcharacterized mby man mincrease mor mdecrease min mthe
meffectiveness mof moneor mboth mof mthe mdrugs. mToxicity mof mone mdrug mmay mor mmay mnot
maffect mthe mmetabolism mof manother mone. mDrug minteractions mmay mresult mfrom meither
mincreased mor mdecreased mpharmacodynamics.
Drug minteractions mmay mresult mfrom meither mincreased mor mdecreased mexcretion.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m8TOP:
Nursing mProcess mStep: mAssessment
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
4. What moccurs mwhen mtwo mdrugs mcompete mfor mthe msame mreceptor msite, mresulting min
mincreased mactivity mof mthe mfirst mdrug?
a. Desired maction
b. Synergistic meffect
c. Carcinogenicity
d. Displacement
ANS: m D
The mdisplacement mof mthe mfirst mdrug mfrom mreceptor msites mby ma msecond mdrug mincreases mthe
mamount mof mthe mfirst mdrug mbecause mmore munbound mdrug mis mavailable. mAn mexpected
mresponse mof ma mdrug mis mthe mdesired maction. mA msynergistic meffect mis mthe meffect mof mtwo
mdrugs mbeing mgreater mthan mthe meffect mof meach mchemical mindividually, mor mthe msum mof mthe
mindividual meffects. mCarcinogenicity mis mthe mability mof ma mdrug mto mcause mcells mto mmutate
mand mbecome mcancerous.
DIF: mCognitive mLevel: mComprehension mREF: mp. m17 mOBJ: m9TOP:
mNursing mProcess mStep: mImplementation
, MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mIntegrity
5. What mdo mdrug mblood mlevels mindicate?
a. They mconfirm mif mthe mpatient mis mtaking ma mgeneric mform mof ma mdrug.
b. They mdetermine mif mthe mpatient mhas msufficient mbody mfat mto mmetabolize mthe mdrug.
c. They mverify mif mthe mpatient m is mtaking msomeone melse’s mmedications.
d. They mdetermine mif mthe mamount mof mdrug min mthe mbody mis min ma mtherapeutic mrange.
ANS: m D
The mamount mof mdrug mpresent mmay mvary mover mtime mand mthe mblood mlevel mmust mremain min ma
therapeutic mrange min morder mto mobtain mthe mdesired c. Drug
mresult. mGeneric mdrugs mdo mnot mnecessarily mproduce ma
d. Therapeuti
mdifferent mdrug mblood mlevel mthan mproprietary c
mmedications. mBody mfat mis mnot mmeasured mby mdrug ANS: m C
mblood mlevels. mDrug mblood mlevels monly mmeasure mthe When
mamount mof mdrug min mthe mbody; mthey mdonot mdetermine ma
mthe msource mof mthe mmedication. mdrug
mis
DIF: mCognitive mLevel: mComprehension mREF: mp. m16 mOBJ: mcircul
m7TOP: mNursing mProcess mStep: mEvaluation ating
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological min
mIntegrity mthe
mblood
6. What mis mthe mprocess mby mwhich ma mdrug mis mtransported mby , ma
mcirculating mbody mfluids mto mreceptor msites? mblood
a. Osmosis msampl
b. Distribution e mmay
c. Absorption mbe
d. Biotransformation mdraw
ANS: m B n mand
massay
Distribution mrefers mto mthe mways min mwhich mdrugs mare ed mto
mtransported mby mthe mcirculating mbody mfluids mtothe msites
mdeter
mof maction m(receptors), mmetabolism, mand mexcretion.
mine
mOsmosis mis mthe mprocess mof mmovingsolution macross ma
mthe
msemipermeable mmembrane mto mequalize mthe mdilution mon
mamou
meach mside.
nt mof
Absorption mis mthe mprocess mby mwhich ma mdrug mis mdrug
mtransferred mfrom mits msite mof mentry minto mthe mbody mto
mprese
mthe mcirculating mfluids mfor mdistribution.
nt;
mBiotransformation, malso mcalled mmetabolism, mis mthe
mthis
mprocess mbywhich mthe mbody minactivates mdrugs.
mis
mknow
DIF: mCognitive mLevel: mComprehension mREF: mp. m13 mOBJ: n mas
m4TOP: mNursing mProcess mStep: mPlanning
mthe
MSC: m NCLEX mClient mNeeds mCategory: mPhysiological mdrug
mIntegrity
mblood
mlevel.
7. The mnurse massesses mwhich mblood mlevel mto mPeak
mdetermine mthe mamount mof mcirculating mmedication mlevels
min mapatient? mare
a. Peak monly
b. Trough mthose
