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, Chapter 01: Introduction to Pathophysiology
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
MULTIPLE CHOICE
1. Which of the following would be the most likely cause of an
iatrogenic disease?
a. An inherited disorder
b. A combination of specific etiological factors
c. An unwanted effect of a prescribed drug
d. Prolonged exposure to toxic chemicals in the environment
ANS: C
2. The manifestations of a disease are best defined as the
a. subjective feelings of discomfort during a chronic illness.
b. signs and symptoms of a disease.
c. factors that precipitate an acute episode of a chronic illness.
d. early indicators of the prodromal stage of infection.
ANS: B
3. The best definition of the term prognosis is the
a. precipitating factors causing an acute episode.
b. number of remissions to be expected during the course of a chronic illness.
c. predicted outcome or likelihood of recovery from a specific disease.
d. exacerbations occurring during chronic illness.
ANS: C
4. Which of the following is considered a systemic sign of disease?
a. Swelling of the knee
b. Fever
c. Pain in the neck
d. Red rash on the face
ANS: B
5. Etiology is defined as the study of the
a. causes of a disease.
b. course of a disease.
c. expected complications of a disease.
d. manifestations of a disease.
ANS: A
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D
7. A change in a tissue marked by cells that vary in size and shape and show increased mitotic
figures would be called
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, a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B
9. When a group of cells in the body dies, the change is called
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cells
undergoing
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A
11. The term cancer refers to
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm.
ANS: D
12. To which of the following does the term apoptosis refer?
a. Increased rate of mitosis by certain cells
b. Ischemic damage to cells
c. Liquefaction of necrotic tissue
d. Preprogrammed cell self-destruction
ANS: D
13. Which of the following statements is TRUE?
a. Alteration of DNA does not change cell function.
b. Damaged cells may be able to repair themselves.
c. All types of cells die at the same rate.
d. Mild ischemia causes immediate cell death.
ANS: B
14. Caseation necrosis refers to an area where
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, a. cell proteins have been denatured.
b. cells are liquefied by enzymes.
c. dead cells form a thick cheesy substance.
d. bacterial invasion has occurred.
ANS: C
15. Routine application of sun block to skin would be an example of
a. an iatrogenic cause of cancer.
b. a preventive measure.
c. a precipitating factor.
d. a predisposing condition.
ANS: B
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
a. latent stage.
b. predisposing factor.
c. incidence.
d. precipitating factor.
ANS: D
17. The term homeostasis refers to
a. the causative factors in a particular disease.
b. maintenance of a stable internal environment.
c. a condition that triggers an acute episode.
d. a collection of signs and symptoms.
ANS: B
18. Which term is used to describe a new and secondary or additional problem that arises after the
original disease has been established?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D
19. Pathophysiology involves the study of
a. the structure of the human body.
b. the functions of various organs in the body.
c. functional or structural changes resulting from disease processes.
d. various cell structures and related functions.
ANS: C
20. Which of the following is the best definition of epidemiology?
a. The science of tracking the occurrence and distribution of diseases
b. The relative number of deaths resulting from a particular disease
c. Identification of a specific disease through evaluation of signs and symptoms
d. The global search for emerging diseases
ANS: A
21. Which of the following can cause cell injury or death?
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, 1. Hypoxia
2. Exposure mto mexcessive mcold
3. Excessive mpressure mon ma mtissue
4. Chemical mtoxins
a. 1, m2
b. 2, m4
c. 1, m3, m4
d. 1, m2, m3, m4
ANS: m D
22. All mof mthe mfollowing mare mpart mof mthe mSeven mSteps mto mHealth mEXCEPT:
a. Follow mcancer mscreening mguidelines.
b. Use msun mblock magents mwhenever mexposed.
c. Participate min mstrenuous mexercise mon ma mregular mdaily mbasis.
d. Choose mhigh mfiber, mlower mfat mfoods.
ANS: m C
23. The mterm mdisease mrefers mto
a. the mperiod mof mrecovery mand mreturn mto ma mnormal mhealthy mstate.
b. a mdeviation mfrom mthe mnormal mstate mof mhealth mand mfunction.
c. the mtreatment mmeasures mused mto mpromote mrecovery.
d. a mbasic mcollection mof msigns mand msymptoms.
ANS: m B
24. A mcollection mof msigns mand msymptoms, moften maffecting mmore mthan mone morgan mor
msystem, mthat musually moccur mtogether min mresponse mto ma mcertain mcondition mis
mreferred mto mas ma(an)
a. acute mdisease.
b. multiorgan mdisorder.
c. syndrome.
d. manifestation.
ANS: m C
25. All mof mthe mfollowing mstatements mare mcorrect mabout mcell mdamage mEXCEPT:
a. The minitial mstage mof mcell mdamage moften mcauses man malteration min mmetabolic mreactions.
b. If mthe mfactor mcausing mthe mdamage mis mremoved mquickly, mthe mcell mmaymbe
mable mto mrecover mand mreturn mto mits mnormal mstate.
c. If mthe mnoxious mfactor mremains mfor man mextended mperiod mof mtime, mthe mdamage
mbecomes mirreversible mand mthe mcell mdies.
d. Initially, mcell mdamage mdoes mnot mchange mcell mmetabolism, mstructure, mor mfunction.
ANS: m D
26. Which mof mthe mfollowing mconditions mdistinguishes mdouble mblind mstudies mused min mhealth mresearch?
a. Neither mthe mmembers mof mthe mcontrol mgroup mor mthe mexperimental mgroup mnor mthe
mperson madministering mthe mtreatment mknows mwho mis mreceiving mthe
mexperimental mtherapy.
b. Both mgroups mof mresearch msubjects mand mthe mperson madministering mthe mtreatment
mknow mwho mis mreceiving mthe mexperimental mtherapy.
c. The mresearch msubjects mdo mnot mknow, mbut mthe mperson madministering mthe
mtreatment mknows mwho mis mreceiving mplacebo mor mstandard mtherapy.
d. Onlymmembers mof mthe mcontrol mgroup mknow mthey mare mreceiving mstandard mtherapy.
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, ANS: m A
27. If mthe mdata mcollected mfrom mthe mresearch mprocess mconfirm mthat mthe mnew mtreatment mhas
mincreased meffectiveness mand mis msafe, mthis mis mcalled
a. the mplacebo meffect.
b. evidence-based mresearch.
c. blind mresearch mstudies.
d. approval mfor mimmediate mdistribution.
ANS: m B
28. A mshort-term millness mthat mdevelops mvery mquickly mwith mperhaps ma mhigh mfever mor
msevere mpain mis mcalled
a. acute.
b. latent.
c. chronic.
d. manifestation.
ANS: m A
29. The mterm mprognosis mrefers mto mthe
a. period mof mrecovery mand mreturn mto ma mnormal mstate.
b. expected moutcome mof mthe mdisease.
c. mortalitymand mmorbidity mrates mfor ma mgiven mpopulation.
d. typical mcollection mof msigns mand msymptoms.
ANS: m B
30. When mprolonged mischemia moccurs mto man marea mof mthe mheart, mthe mresulting mdamage mis mreferred mto mas
a. atrophy.
b. liquefactive mnecrosis.
c. apoptosis.
d. infarction.
ANS: m D
31. During mthe mevaluation mprocess mfor ma mnew mtherapy’s meffectiveness mand msafety, ma
mdouble mblind mstudy mmay mbe mconducted mduring
a. the mfirst mstage.
b. the msecond mstage.
c. the mthird mstage.
d. anymof mthese mstages.
ANS: m C
32. Whymare mthe mpredisposing mfactors mfor ma mspecific mdisease mimportant mto mhealth mprofessionals?
a. To mpredict mthe mprognosis
b. To mdetermine mtreatments
c. To mdevelop mpreventive mmeasures
d. To mdevelop mmorbiditymstatistics
ANS: m C
33. Cell mdamage mmaymbe mcaused mby mexogenous msources msuch mas
a. abnormal mmetabolic mprocesses.
b. certain mfood madditives.
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, c. genetic mdefects.
d. localized mhypoxia.
ANS: m B
34. Which mof mthe mfollowing mis musuallymincluded min ma mmedical mhistory?
1. Past millnesses mor msurgeries
2. Current millnesses, macute mand mchronic
3. Prescribed mmedication mor mother mtreatments
4. Nonprescription mdrugs mand mherbal mremedies
5. Current mallergies
a. 1, m3
b. 2, m4, m5
c. 1, m3, m4
d. 1, m2, m3, m4, m5
ANS: m D
35. A msituation mwhen mthere mis ma mhigher mthan mexpected mnumber mof mcases mof man minfectious
mdisease mwithin ma mgiven marea mis mcalled ma/an
a. epidemic.
b. exacerbation.
c. morbidity.
d. pandemic.
ANS: m A
36. The mterm mpathogenesis mrefers mto
a. the mdevelopment mof ma mdisease mor msequence mof mevents mrelated mto mtissue
mchanges minvolved min mthe mdisease mprocess.
b. the mdetermination mof mthe mcause(s) minvolved min mthe mdevelopment mof ma
mmalignant mneoplasm.
c. the mspecific msigns mand msymptoms minvolved min mthe mchange mfrom man macute
mdisease mto ma mchronic mdisease.
d. the mchanges min mcells mof maffected mtissue mthat mresult min mnecrosis.
ANS: m A
37. A mtherapy mthat mhas mbeen mapproved mfor muse mand mmay mshow madditional mpotential
mto mtreat ma mdifferent mdisease mis mtermed m“ ” muse.
a. over-the-counter
b. off-label
c. additional
d. conditional
ANS: m B
38. A mpotential munwanted moutcome mof ma mprimary mcondition, msuch mas mparalysis
mfollowing mthe mrecovery mfrom ma mstroke, mis mreferred mto mas
a. complication.
b. convalescence.
c. sequelae.
d. postcondition.
ANS: m C
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, 39. An minfectious mdisease mthat mspreads mover mwide mregions mof mthe mglobe mis mcalled ma(an)
a. pandemic.
b. endemic.
c. epidemic.
d. periodic.
ANS: m A
40. The mtype mof mnecrosis mthat moccurs mwhen mcell mproteins mare maltered mor mdenatured mis mreferred mto
mas
a. liquefaction mnecrosis.
b. coagulative mnecrosis.
c. degenerative mnecrosis.
d. caseous mnecrosis.
ANS: m B
Chapter m02: mFluid, mElectrolyte, mand mAcid-Base mImbalances
VanMeter mand mHubert: mGould’s mPathophysiology mfor mthe mHealth mProfessions, m7th
mEdition
MULTIPLE mCHOICE
1. Choose mthe mcorrect mproportion mof mwater mto mbody mweight mto mbe mexpected min ma
mhealthy mmale madult’s mbody:
a. 30%
b. 45%
c. 60%
d. 70%
ANS: m C
2. Choose mthe mcorrect mproportion mof mblood m(to mbodymweight) min man madult mmale’s mbody:
a. 30%
b. 20%
c. 10%
d. 4%
ANS: m D
3. Which mof mthe mfollowing mis mNOT mpart mof mthe mextracellular mfluid mcompartment m(ECF)?
a. Blood
b. Cytoplasm
c. Cerebrospinal m fluid
d. Transcellular mfluid
ANS: m B
4. Insensible mfluid mloss mrefers mto mwater mlost mthrough
a. perspiration m only.
b. feces monly.
c. perspiration mand mexpiration.
d. urine mand mfeces.
ANS: m C
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