NR 293 // Ch 50 - Acid-Controlling Drugs
Questions With Complete Solutions
Acid-Related Diseases Correct Answers -caused
by imbalance of 3 cells of gastric gland and their
secretions
-most common is hyperacidity
Antacids Correct Answers -OTC available as:
capsules, tabs, powders, chewables, suspensions,
effervescent granules/tabs
-used alone or in combo w/: aluminum salts,
magnesium salts, calcium salts, sodium bicarb
Antacids - Adverse Effects Correct Answers -
minimal, and depdn on compound used
-Al and Ca: constipation
-Mg: diarrhea
-Ca carbonate: produces gas, belching
Antacids - Aluminum Salt Examples Correct
Answers -aluminum carbonate (Basaljel)
-hydroxide salt (AlternaGEL)
-combo products (Al and Mg) (Gaviscon, Maalox,
Mylanta, Di-Gel)
Antacids - Aluminum Salts Correct Answers -have
constipating effects
-often used w magnesium to counteract the
constipation
, -often recommended for pts w renal dx (more
easily excreted)
Antacids - Calcium Salt Examples Correct Answers
-Tums (calcium carbonate)
Antacids - Calcium Salts Correct Answers -many
forms, but carbonate is most common
-may cause constipation, kidney stones
-not recommended for pt w renal dx
(accumulation)
-long duration of acid action - may cause rebound
hyperacidity)
-often advertised as extra source of dietary calcium
Antacids - Drug Effects Correct Answers -
reduction of pain associated w acid-related dx
-raising gastric pH from 1.3-1.6 neutralizes 50% of
the gastric acid
-raising gastric pH 1 point neutralizes 90% of
gastric acid
-reducing acidity reduces pain
Antacids - Drug Interactions Correct Answers -
absorption of other drugs to antacids - reduces
ability of other drugs to be absorbed into the body
-chelation
-incr stomach pH (incr absorption of basic drugs,
decr absorption of acidic drugs)
Questions With Complete Solutions
Acid-Related Diseases Correct Answers -caused
by imbalance of 3 cells of gastric gland and their
secretions
-most common is hyperacidity
Antacids Correct Answers -OTC available as:
capsules, tabs, powders, chewables, suspensions,
effervescent granules/tabs
-used alone or in combo w/: aluminum salts,
magnesium salts, calcium salts, sodium bicarb
Antacids - Adverse Effects Correct Answers -
minimal, and depdn on compound used
-Al and Ca: constipation
-Mg: diarrhea
-Ca carbonate: produces gas, belching
Antacids - Aluminum Salt Examples Correct
Answers -aluminum carbonate (Basaljel)
-hydroxide salt (AlternaGEL)
-combo products (Al and Mg) (Gaviscon, Maalox,
Mylanta, Di-Gel)
Antacids - Aluminum Salts Correct Answers -have
constipating effects
-often used w magnesium to counteract the
constipation
, -often recommended for pts w renal dx (more
easily excreted)
Antacids - Calcium Salt Examples Correct Answers
-Tums (calcium carbonate)
Antacids - Calcium Salts Correct Answers -many
forms, but carbonate is most common
-may cause constipation, kidney stones
-not recommended for pt w renal dx
(accumulation)
-long duration of acid action - may cause rebound
hyperacidity)
-often advertised as extra source of dietary calcium
Antacids - Drug Effects Correct Answers -
reduction of pain associated w acid-related dx
-raising gastric pH from 1.3-1.6 neutralizes 50% of
the gastric acid
-raising gastric pH 1 point neutralizes 90% of
gastric acid
-reducing acidity reduces pain
Antacids - Drug Interactions Correct Answers -
absorption of other drugs to antacids - reduces
ability of other drugs to be absorbed into the body
-chelation
-incr stomach pH (incr absorption of basic drugs,
decr absorption of acidic drugs)
