s
Introduction to Genetic Analysis
s s s
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
s s s s s s s s s s
12th Edition
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,Table of Contents
s s
Chapters01sThesGeneticssRevolution 1
Chapters02sSinglesGenesInheritance 6
Chapters03sIndependentsAssortmentsofsGenes 26
Chapters04sMappingsEukaryotesChromosomessbysRecombination 43
Chapters05sGenesInteraction 63
Chapters06sThesGeneticssofsBacteriasandsTheirsViruses 84
Chapters07sDNAsStructuresandsReplication 104
Chapters08sRNAsTranscriptionsProcessingsandsDecay 117
Chapters09sProteinssandsTheirsSynthesis 130
Chapters10sGenesIsolationsandsManipulation 141
Chapters11sRegulationsofsGenesExpressionsinsBacteriasandsTheirsViruses 160
Chapters12sRegulationsofsGenesExpressionsinsEukaryotes 175
Chapters13sThesGeneticsControlsofsDevelopment 184
Chapters14sGenomessandsGenomics 192
Chapters15sDNAsDamagesRepairsandsRecombination 197
Chapters16sThesDynamicsGenomesTransposablesElements 216
Chapters17sLargesScalesChromosomalsChanges 225
Chapters18sPopulationsGenetics 243
Chapters19sThesInheritancesofsComplexsTraits 258
Chapters20sEvolutionsofsGenessandsTraits 270
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Chapters01:sThesGeneticssRevolution
1. Thesearlys1900sswassansimportantsperiodsforsgeneticssduestoswhichsofsthesfollowingsmajorsevents?
a. thesrediscoverysofsGregorsMendel'ssscientificsfindings
b. WatsonsandsCrickssolvingsthesstructuresofsDNA
c. WaltersSuttonsandsTheodoresBoverishypothesizingsthatschromosomessarestheshereditaryselements
d. thesrediscoverysofsGregorsMendel'ssscientificsfindingssandsWaltersSuttonsandsTheodoresBoverishy
pothesizingsthatschromosomessarestheshereditaryselements
e. Allsofsthesanswersoptionssarescorrect.
ANSWER:s e
2. Assamplesofsnormalsdouble-
strandedsDNAswassfoundstoshavesasguaninescontentsofs18%.sWhatsissthesexpectedsproportionsofsadenine?
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER:s b
3. InsonesstrandsofsDNA,sthesnucleotidessequencesiss5'-ATGC-
3'.sThescomplementaryssequencesinsthesothersstrandsmustsbe
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER:s b
4. HowsmanysdifferentsDNAsmoleculessthatsareseight-nucleotide-pairsslongsarestheoreticallyspossible?
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER:s e
5. Whichsofsthesfollowingsis/aresTRUEsaboutsgenes?
a. Genessareslocatedsonschromosomes.
b. Genesscomesinsvariantssknownsassalleles.
c. Genessusuallysencodesproteinsproducts.
d. Allsofsthesanswersoptionssarescorrect.
e. Nonesofsthesanswersoptionssisscorrect.
ANSWER:s d
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6. Wildscatss(Felisssilvestris)sandscommonsmices(Mussmusculus)saresdiploid.sInswildscats,s2ns=s38,swhilesinsco
mmonsmice,s2ns=s40.sBasedsonsthissinformation,swescansconcludesthatswild-catscellsshave
a. lesssDNAsthanscommon-mousescells.
b. smallersgenomessthanscommon-mousescells.
c. fewersDNAsmoleculessthanscommon-mousescells.
d. fewersgenessthanscommon-mousescells.
e. fewerssetssofschromosomessthanscommon-mousescells.
ANSWER:s c
7. WhichsofsthesfollowingsissascomponentsofsDNA?
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER:s d
8. Whichsofsthesfollowingsis/aresTRUEsofsthesDNAsstructuressolvedsbysWatsonsandsCrick?
a. Itsissasdouble-helicalsstructure.
b. Sugar–phosphatesbackbonesissalwaysstowardsthesoutsidesofsthesDNA.
c. TheresarestwoshydrogensbondssbetweensAsandsTsandsthreeshydrogensbondssbetweensCsandsG.
d. Theresaresfourstypessofsnitrogenoussbases.
e. Allsofsthesanswersoptionssarescorrect.
ANSWER:s e
9. WhichsofsthesfollowingsissasCORRECTsrepresentationsofsthescentralsdogma?
a. RNAs→sDNAs→sprotein
b. proteins→sDNAs→sRNA
c. DNAs→sRNAs→sprotein
d. DNAs→sproteins→sDNA
e. Nonesofsthesanswersoptionssisscorrect.
ANSWER:s c
10. Youshavescomesacrosssasdogs(namedsCindy)sthatsdoessnotshavesastail.sInterestingly,sallsthespuppiessproducedsbyst
hissdogsdon'tshavesastail.sIfstheslacksofstailsisscausedsbysasgeneticsmutation,swhereshassthissmutationsmostslikelystakens
place?
a. insCindy'ssgametes
b. insthescellssthatsshouldsnormallyshavesgivensrisestosCindy'sstail
c. insthescellssthatsshouldsnormallyshavesgivensrisestosCindy'ssandsherspuppies'stails
d. insallsofsCindy'sscellss(includingshersgametes)
e. insasgametesofsonesofsCindy'ssparents
ANSWER:s a
11. Whichsofsthesfollowingsfeaturessmakessasspeciesssuitablesassasmodelsorganism?
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