What CSMLS MOCK EXAM questions and
answers 100% guaranteed success.
What is a CBC ? correct answer.Complete Blood Count, an evaluation of formed
elements of blood , RBCs , WBCs and platelets . EDTA whole blood maintains the cell's
shape and size. preventing blood from clotting by binding by calcium
What is required for blood film preparation? correct answer.The object is to spread
the cells in monolayer without distorting them . The blood film is important in the
investigation and the management of blood cell disease
What is unique about the thickness of blood film ? correct answer.If the Hb is increased
, the angle of the spreader should be decreased. If the Hb is decreased theangle of the
spreader should be increased
What are the features of a well made blood film ? correct answer.Correct size drop of
blood
Film is 2/3 of the length of the slide
Film is finger shaped with a slightly rounded feathered edge
Angle of the spreader should be 35 degrees
Film is smooth with no holes or streaks
What are the steps required when staining and fixing a blood film ? correct answer.Allow
blood film to dry completely before staining. Do not blow dry as moisturefrom breath will
cause RBC artifact. Methanol is thge fixative of choice , stain has methanol. Timing and
pH are critical
What are coagulation tests? correct answer.Plasma is required. Citrate is the
anticoagulant of PT + PTT. Sodium citrate binds to calcium preventing coagulation.
Tubes must be drawn full capacity
What is Hemoglobinopathy? correct answer.Abnormal chain of Hb
,What is Thalassemia ? correct answer.Failure to produce alpha or beta chains
What is the Hb Normal value for Infants ? correct answer.160 - 230 g/L
What is the Hb Normal value for a Toddler ? correct answer.> 100 g/L
What is the Hb Normal value for a male? correct answer.140-180 g/ L
What is the Hb Normal value for a female ? correct answer.120- 160 g/L
What are the critical Hb values ? correct answer.Low < 60 g/L , causes bleeding /
heart failure
High > 200 g/L polycythemia, severe burns, chronic obstructive pulmonary disease and
CHF
What is Hematocrit? correct answer.Also called PCV. Micro Hct is the volume of
RBCs after centrifuging whole blood for 5 minutes @ 12, 000 rpm. Comprises RBCs
that are normally 40 - 50 % of blood volume. Requires a small volume of blood.
Lavender top tube, venous blood or capillary blood collected directly into heparinized
capillary tubes. SHould be centrifuged within 4 hours of collection
What is the Hct Normal value for an infant? correct answer.0.50 - 0.60
What is the Hct Normal value for a toddler? correct answer.0.35 -0.42
What is the Hct Normal value for a male ? correct answer.0.40-0.50
What is the Hct normal value for a female? correct answer.0.35-0.50
What is the Hct Critical Values? correct answer.< 0.20 and > 0.60
What are some of the sources of error for Hct? correct answer.Improper sealing of
capillary tube (D) due to loss of RBCs
Increase concentration of anticoagulant (D) due to unfilled tube
Improper mixing of blood (I) or (D)
Time & speed of centrifuge (I) due to trapped plasma
Improper collection of specimen (I) or (D)
Delay in reading (I) due to packing of RBC
Buffy coat included (I)
What is the structure of a WBC? correct answer.Approx 10 - 20 um in diameter (2-3 size
of RBC) , can count under 400 X magnification (high dry) can see detail under 1000X
magnification (oil immersion) , cells are nucleated , flexible membrane variable shape,
resists lysis types: granulocytes, lymphoctyes, monocytes
,What is required for the manual WBC Principle Count ? correct answer.Dilute blood
3 3 3 3 3 3 3 3 3 3 3 3
with fluid that lyses RBCs and stains WBCs, counts the WBCs in a known volume of
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
blood, calculate cells / L
3 3 3 3 3
What is the normal value of WBC in an adult? correct answer.4.5 -11.0 x10 9/L
3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the normal value of WBC in an infant ? correct answer.9.0 - 30.0 x 10 9/ L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the critical value for WBC? correct answer.< 1x10 9 /L and > 50 x 10 9 / L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the RBC Principle Count? correct answer.Dilute well mixed EDTA blood with
3 3 3 3 3 3 3 3 3 3 3 3
isotonic fluid, count RBCs in an known volume of blood. Calculate cells/ L
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the RBC normal value for a male? correct answer.4.5 - 6.0 x 10 12 / L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the normal RBC value for a female? correct answer.4.0 - 5.5 x 10 12/L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is ESR ? correct answer.Rate at which RBCs fall within a set time. Rouleaux,
3 3 3 3 3 3 3 3 3 3 3 3 3 3
fibrinogen and globulin increase ESR, high RBC some RBC shapes will decrease ESR
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Manual Westergreen Method? correct answer.200 nm open ended tube
3 3 3 3 3 3 3 3 3 3 3
specimen sample EDTA blood diluted 4:1 with citrate black tube. Use pipette filler to fill
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
ESR tube until cotton is wet to prevent leaking. Set up vertically in rack, record mm of
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
RBCs that fell in an hour
3 3 3 3 3 3
What is the Westergreen Method normal range for a male ? correct answer.0-15 mm
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Westergreen Method normal range for a female ? correct answer.0-20
3 3 3 3 3 3 3 3 3 3 3 3
mm
3
What is the Westergreen Method reference range for both males and females? correct
3 3 3 3 3 3 3 3 3 3 3 3
answer.0-9 mm / hour
3 3 3 3
What are some of the falsely increased factors of ESR? correct answer.Tube not
3 3 3 3 3 3 3 3 3 3 3 3
vertical
3
Incorrect timing 3
3Boom temp > 25 3 3 3
3C
Incorrect mixing of sample 3 3 3
3Vibration of tube during 3 3 3
3test
What are some of the falsely decreased factors of ESR? correct answer.Air bubblesin
3 3 3 3 3 3 3 3 3 3 3 3 3
3tube
Incorrect timing ( too short) 3 3 3 3
Blood specimen below RT
3 3 3 3
3Fibrin clots 3
Hemolyzed sample 3
, What are malaria smears ? correct answer.Caused by the intracellular parasite,
3 3 3 3 3 3 3 3 3 3
3plasmodium which is transmitted via the bites of infected mosquitoes. In the human
3 3 3 3 3 3 3 3 3 3 3 3
3body the parasite multiply in the liver and infects RBCs. Symptoms of malaria include ;
3 3 3 3 3 3 3 3 3 3 3 3 3 3
fever, headache, vomitting, and usually appear 10 - 15 days after bite
3 3 3 3 3 3 3 3 3 3 3 3
What is required for thick smears? correct answer.Prepare smear using capillary blood
3 3 3 3 3 3 3 3 3 3 3
or EDTA blood spread droplet of blood using spreader slide in a circular motion . Let
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
dry, stain without fixing using Geimsa. RBCs are lysed and film can be examined for
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
parasites . Plasmodium sttains blue with blue chromatin dot
3 3 3 3 3 3 3 3 3
What is required for thin smears? correct answer.Prepare smear using capillary or
3 3 3 3 3 3 3 3 3 3 3
EDTA blood. Spread droplet of blood using spreader slide in a circular motion. Let dry
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
stain without using Gesima. RBCs are lysed and film can be examined for parasites.
3 3 3 3 3 3 3 3 3 3 3 3 3 3
Plasmodium stains red chromatin dot
3 3 3 3 3
What is a Reticulocyte? correct answer.Is an immuature RB, cell has no nucleus, RNA
3 3 3 3 3 3 3 3 3 3 3 3 3
is still present in the cytoplasm . RNA is basophilic. Retic count is a measure ofRBC
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
prpduction
3
What is known as Retic Theory? correct answer.Is a super vital stain procedure that
3 3 3 3 3 3 3 3 3 3 3 3 3
uses living cells super vital stains such as New Methylene Blue or Brilliant Blue Dye
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Retic Manual Method? correct answer.Mix equal parts of EDTA blood and
3 3 3 3 3 3 3 3 3 3 3 3 3
stain. Let stand for 15 minutes , at least 2 smears are made up of stained cells layon a
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
flat surface to air dry, total 1000 RBCs counted 500/ slide # of retics counted / 1000
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
RBCs is recorded
3 3 3
What is the Retic reference range for an adult ? correct answer.0.5 - 1.5 %
3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Retic reference range for newborns ? correct answer.2.5- 6.5 %
3 3 3 3 3 3 3 3 3 3 3 3
What are the increased sources of error for Retics? correct answer.Hemolytic anemia
3 3 3 3 3 3 3 3 3 3 3
Acute blood loss
3 3 3
Response to placement therapy 3 3 3
What are the decreased sources of error for Retics? correct answer.Aplastic anemia
3 3 3 3 3 3 3 3 3 3 3
Marrow suppression
3 3
What is required for Sickle Cell Preparation? correct answer.Drop of blood mixed with2
3 3 3 3 3 3 3 3 3 3 3 3 3
% Metabisulphite on a slide, seal mixture, coverslip and let sit for 30 minutes,
3 3 3 3 3 3 3 3 3 3 3 3 3 3
decreased oxygen will cause Hbs to polymerize and cause RBCs to sickle
3 3 3 3 3 3 3 3 3 3 3 3
What is Sickle Cell Solubility Screening? correct answer.The most common , Hb S is
3 3 3 3 3 3 3 3 3 3 3 3 3
mixed with a phosphate buffer and reducing reagent is insoluble and precipitates in
3 3 3 3 3 3 3 3 3 3 3 3 3
solution appearing turbid
3 3 3
answers 100% guaranteed success.
What is a CBC ? correct answer.Complete Blood Count, an evaluation of formed
elements of blood , RBCs , WBCs and platelets . EDTA whole blood maintains the cell's
shape and size. preventing blood from clotting by binding by calcium
What is required for blood film preparation? correct answer.The object is to spread
the cells in monolayer without distorting them . The blood film is important in the
investigation and the management of blood cell disease
What is unique about the thickness of blood film ? correct answer.If the Hb is increased
, the angle of the spreader should be decreased. If the Hb is decreased theangle of the
spreader should be increased
What are the features of a well made blood film ? correct answer.Correct size drop of
blood
Film is 2/3 of the length of the slide
Film is finger shaped with a slightly rounded feathered edge
Angle of the spreader should be 35 degrees
Film is smooth with no holes or streaks
What are the steps required when staining and fixing a blood film ? correct answer.Allow
blood film to dry completely before staining. Do not blow dry as moisturefrom breath will
cause RBC artifact. Methanol is thge fixative of choice , stain has methanol. Timing and
pH are critical
What are coagulation tests? correct answer.Plasma is required. Citrate is the
anticoagulant of PT + PTT. Sodium citrate binds to calcium preventing coagulation.
Tubes must be drawn full capacity
What is Hemoglobinopathy? correct answer.Abnormal chain of Hb
,What is Thalassemia ? correct answer.Failure to produce alpha or beta chains
What is the Hb Normal value for Infants ? correct answer.160 - 230 g/L
What is the Hb Normal value for a Toddler ? correct answer.> 100 g/L
What is the Hb Normal value for a male? correct answer.140-180 g/ L
What is the Hb Normal value for a female ? correct answer.120- 160 g/L
What are the critical Hb values ? correct answer.Low < 60 g/L , causes bleeding /
heart failure
High > 200 g/L polycythemia, severe burns, chronic obstructive pulmonary disease and
CHF
What is Hematocrit? correct answer.Also called PCV. Micro Hct is the volume of
RBCs after centrifuging whole blood for 5 minutes @ 12, 000 rpm. Comprises RBCs
that are normally 40 - 50 % of blood volume. Requires a small volume of blood.
Lavender top tube, venous blood or capillary blood collected directly into heparinized
capillary tubes. SHould be centrifuged within 4 hours of collection
What is the Hct Normal value for an infant? correct answer.0.50 - 0.60
What is the Hct Normal value for a toddler? correct answer.0.35 -0.42
What is the Hct Normal value for a male ? correct answer.0.40-0.50
What is the Hct normal value for a female? correct answer.0.35-0.50
What is the Hct Critical Values? correct answer.< 0.20 and > 0.60
What are some of the sources of error for Hct? correct answer.Improper sealing of
capillary tube (D) due to loss of RBCs
Increase concentration of anticoagulant (D) due to unfilled tube
Improper mixing of blood (I) or (D)
Time & speed of centrifuge (I) due to trapped plasma
Improper collection of specimen (I) or (D)
Delay in reading (I) due to packing of RBC
Buffy coat included (I)
What is the structure of a WBC? correct answer.Approx 10 - 20 um in diameter (2-3 size
of RBC) , can count under 400 X magnification (high dry) can see detail under 1000X
magnification (oil immersion) , cells are nucleated , flexible membrane variable shape,
resists lysis types: granulocytes, lymphoctyes, monocytes
,What is required for the manual WBC Principle Count ? correct answer.Dilute blood
3 3 3 3 3 3 3 3 3 3 3 3
with fluid that lyses RBCs and stains WBCs, counts the WBCs in a known volume of
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
blood, calculate cells / L
3 3 3 3 3
What is the normal value of WBC in an adult? correct answer.4.5 -11.0 x10 9/L
3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the normal value of WBC in an infant ? correct answer.9.0 - 30.0 x 10 9/ L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the critical value for WBC? correct answer.< 1x10 9 /L and > 50 x 10 9 / L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the RBC Principle Count? correct answer.Dilute well mixed EDTA blood with
3 3 3 3 3 3 3 3 3 3 3 3
isotonic fluid, count RBCs in an known volume of blood. Calculate cells/ L
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the RBC normal value for a male? correct answer.4.5 - 6.0 x 10 12 / L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the normal RBC value for a female? correct answer.4.0 - 5.5 x 10 12/L
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is ESR ? correct answer.Rate at which RBCs fall within a set time. Rouleaux,
3 3 3 3 3 3 3 3 3 3 3 3 3 3
fibrinogen and globulin increase ESR, high RBC some RBC shapes will decrease ESR
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Manual Westergreen Method? correct answer.200 nm open ended tube
3 3 3 3 3 3 3 3 3 3 3
specimen sample EDTA blood diluted 4:1 with citrate black tube. Use pipette filler to fill
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
ESR tube until cotton is wet to prevent leaking. Set up vertically in rack, record mm of
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
RBCs that fell in an hour
3 3 3 3 3 3
What is the Westergreen Method normal range for a male ? correct answer.0-15 mm
3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Westergreen Method normal range for a female ? correct answer.0-20
3 3 3 3 3 3 3 3 3 3 3 3
mm
3
What is the Westergreen Method reference range for both males and females? correct
3 3 3 3 3 3 3 3 3 3 3 3
answer.0-9 mm / hour
3 3 3 3
What are some of the falsely increased factors of ESR? correct answer.Tube not
3 3 3 3 3 3 3 3 3 3 3 3
vertical
3
Incorrect timing 3
3Boom temp > 25 3 3 3
3C
Incorrect mixing of sample 3 3 3
3Vibration of tube during 3 3 3
3test
What are some of the falsely decreased factors of ESR? correct answer.Air bubblesin
3 3 3 3 3 3 3 3 3 3 3 3 3
3tube
Incorrect timing ( too short) 3 3 3 3
Blood specimen below RT
3 3 3 3
3Fibrin clots 3
Hemolyzed sample 3
, What are malaria smears ? correct answer.Caused by the intracellular parasite,
3 3 3 3 3 3 3 3 3 3
3plasmodium which is transmitted via the bites of infected mosquitoes. In the human
3 3 3 3 3 3 3 3 3 3 3 3
3body the parasite multiply in the liver and infects RBCs. Symptoms of malaria include ;
3 3 3 3 3 3 3 3 3 3 3 3 3 3
fever, headache, vomitting, and usually appear 10 - 15 days after bite
3 3 3 3 3 3 3 3 3 3 3 3
What is required for thick smears? correct answer.Prepare smear using capillary blood
3 3 3 3 3 3 3 3 3 3 3
or EDTA blood spread droplet of blood using spreader slide in a circular motion . Let
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
dry, stain without fixing using Geimsa. RBCs are lysed and film can be examined for
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
parasites . Plasmodium sttains blue with blue chromatin dot
3 3 3 3 3 3 3 3 3
What is required for thin smears? correct answer.Prepare smear using capillary or
3 3 3 3 3 3 3 3 3 3 3
EDTA blood. Spread droplet of blood using spreader slide in a circular motion. Let dry
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
stain without using Gesima. RBCs are lysed and film can be examined for parasites.
3 3 3 3 3 3 3 3 3 3 3 3 3 3
Plasmodium stains red chromatin dot
3 3 3 3 3
What is a Reticulocyte? correct answer.Is an immuature RB, cell has no nucleus, RNA
3 3 3 3 3 3 3 3 3 3 3 3 3
is still present in the cytoplasm . RNA is basophilic. Retic count is a measure ofRBC
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
prpduction
3
What is known as Retic Theory? correct answer.Is a super vital stain procedure that
3 3 3 3 3 3 3 3 3 3 3 3 3
uses living cells super vital stains such as New Methylene Blue or Brilliant Blue Dye
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Retic Manual Method? correct answer.Mix equal parts of EDTA blood and
3 3 3 3 3 3 3 3 3 3 3 3 3
stain. Let stand for 15 minutes , at least 2 smears are made up of stained cells layon a
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
flat surface to air dry, total 1000 RBCs counted 500/ slide # of retics counted / 1000
3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3
RBCs is recorded
3 3 3
What is the Retic reference range for an adult ? correct answer.0.5 - 1.5 %
3 3 3 3 3 3 3 3 3 3 3 3 3 3
What is the Retic reference range for newborns ? correct answer.2.5- 6.5 %
3 3 3 3 3 3 3 3 3 3 3 3
What are the increased sources of error for Retics? correct answer.Hemolytic anemia
3 3 3 3 3 3 3 3 3 3 3
Acute blood loss
3 3 3
Response to placement therapy 3 3 3
What are the decreased sources of error for Retics? correct answer.Aplastic anemia
3 3 3 3 3 3 3 3 3 3 3
Marrow suppression
3 3
What is required for Sickle Cell Preparation? correct answer.Drop of blood mixed with2
3 3 3 3 3 3 3 3 3 3 3 3 3
% Metabisulphite on a slide, seal mixture, coverslip and let sit for 30 minutes,
3 3 3 3 3 3 3 3 3 3 3 3 3 3
decreased oxygen will cause Hbs to polymerize and cause RBCs to sickle
3 3 3 3 3 3 3 3 3 3 3 3
What is Sickle Cell Solubility Screening? correct answer.The most common , Hb S is
3 3 3 3 3 3 3 3 3 3 3 3 3
mixed with a phosphate buffer and reducing reagent is insoluble and precipitates in
3 3 3 3 3 3 3 3 3 3 3 3 3
solution appearing turbid
3 3 3
